Lorna O&#x;Donoghue,Albert Smolenski
Lorna O&#x;Donoghue
Platelets are small anucleate blood cells supporting vascular function. They circulate in a quiescent state monitoring the vasculature for injuries. Platelets adhere to injury sites and can be rapidly activated to secrete granules and to fo...
Isoflurane increases the activity of the vascular matrix metalloproteinase-2 in non-pregnant rats and increases the nitric oxide metabolites in pregnancy [0.03%]
异氟醚可提高非孕大鼠血管基质金属蛋白酶-2活性并增加妊娠时期的代谢物硝酸氧化物
Carolina Rosa Rodrigues Souza,Edileia Souza Paula Caetano,Serginara David Rodrigues et al.
Carolina Rosa Rodrigues Souza et al.
Surgeries that require general anesthesia occur in 1.5-2% of gestations. Isoflurane is frequently used because of its lower possibility of affecting fetal growth. Therefore, we examined the isoflurane anesthesia-induced effects on maternal ...
Co-localization of the sodium-glucose co-transporter-2 channel (SGLT-2) with endothelin ETA and ETB receptors in human cardiorenal tissue [0.03%]
人心脏肾脏组织中钠葡萄糖共转运体-2通道（SGLT-2）与内皮素ETA和ETB受体的共定位
Thomas L Williams,Rhoda E Kuc,Anna L Paterson et al.
Thomas L Williams et al.
Endothelin (ET) receptor antagonists are being investigated in combination with sodium-glucose co-transporter-2 inhibitors (SGLT-2i). These drugs primarily inhibit the SGLT-2 transporter that, in humans, is thought to be mainly restricted t...
Retraction: Downregulated microRNA-30b-3p inhibits proliferation, invasion and migration of glioma cells via inactivation of the AKT signaling pathway by upregulating RECK [0.03%]
撤稿：通过上调RECK来抑制AKT信号通路，下调的microRNA-30b-3p可抑制胶质瘤细胞的增殖、侵袭和迁移
Retraction of Publication
Bioscience reports. 2024 May 29;44(5):BSR-2018-2226_RET. DOI:10.1042/BSR-2018-2226_RET 2024
Loci cg06256735 and cg15815843 in the MFAP5 gene regulatory regions are hypomethylated in varicose veins apparently due to active demethylation [0.03%]
MFAP5基因调控区域的两个位点cg06256735和cg15815843在静脉曲张中低甲基化且似乎是由于去甲基化所致
Mariya A Smetanina,Valeria A Korolenya,Fedor A Sipin et al.
Mariya A Smetanina et al.
Varicose vein disease (VVD) is a common health problem worldwide. Microfibril-associated protein 5 (MFAP5) is one of the potential key players in its pathogenesis. Our previous microarray analysis revealed the cg06256735 and cg15815843 loci...
Temozolomide resistance mechanisms: unveiling the role of translesion DNA polymerase kappa in glioblastoma spheroids in vitro [0.03%]
替莫唑胺耐药机制：揭示跨损伤DNA聚合酶κ在胶质母细胞瘤类器官中体外作用机制
Diego Luis Ribeiro,Marcela Teatin Latancia,Izadora de Souza et al.
Diego Luis Ribeiro et al.
Temozolomide (TMZ) is the leading therapeutic agent for combating Glioblastoma Multiforme (GBM). Nonetheless, the persistence of chemotherapy-resistant GBM cells remains an ongoing challenge, attributed to various factors, including the tra...
Retraction: Lycium barbarum polysaccharide induced apoptosis and inhibited proliferation in infantile hemangioma endothelial cells via down-regulation of PI3K/AKT signaling pathway [0.03%]
撤回：通过下调PI3K / AKT信号通路诱导婴儿血管内皮细胞凋亡和抑制增殖的枸杞多糖
Retraction of Publication
Bioscience reports. 2024 May 29;44(5):BSR-2019-1182_RET. DOI:10.1042/BSR-2019-1182_RET 2024
Antiviral effect of baicalein on Porcine Deltacoronavirus infection by regulating the inflammatory responses through PI3K-Akt-NF-κB signaling pathway in cultured cells [0.03%]
黄芩素通过PI3K-Akt-NF-κB信号通路调节炎症反应抑制猪德尔塔冠状病毒感染的体外抗病毒作用研究
Hejuan Liu,Zhanyong Wei,Chenxi Shi et al.
Hejuan Liu et al.
Porcine deltacoronavirus (PDCoV) is an newly emerged enteropathogenic coronavirus, mainly causing diarrhea in suckling piglets, and also has the potential for cross-species transmission. However, there are no effective vaccines or specific ...
sFlt-1 impairs neurite growth and neuronal differentiation in SH-SY5Y cells and human neurons [0.03%]
sFlt-1抑制SH-SY5Y细胞和人神经元的突触生长和神经元分化
Aaron Barron,Lauren Barrett,Jetro J Tuulari et al.
Aaron Barron et al.
Pre-eclampsia (PE) is a hypertensive disorder of pregnancy which is associated with increased risk of neurodevelopmental disorders in exposed offspring. The pathophysiological mechanisms mediating this relationship are currently unknown, an...