Microarray analysis demonstrates up-regulation of the endothelin-1 gene with compensatory down-regulation of the ETA receptor gene in human portal vein [0.03%]
微阵列分析表明内皮素-1基因上调和人门静脉ETA受体基因的补偿下调
Nicola E Owen,Thomas L Williams,Janet J Maguire et al.
Nicola E Owen et al.
High blood pressure in the portal vein, portal hypertension (PH), is the final common pathway in liver cirrhosis regardless of aetiology. Complications from PH are the major cause of morbidity and mortality in these patients. Current drug t...
Spatiotemporal regulation of the hepatocyte growth factor receptor MET activity by sorting nexins 1/2 in HCT116 colorectal cancer cells [0.03%]
Sorting受体衔接蛋白Sorting nexin 1/2调控结肠癌HCT116细胞中MET信号的空间和时间模式
Laiyen Garcia Delgado,Amélie Derome,Samantha Longpré et al.
Laiyen Garcia Delgado et al.
Cumulative research findings support the idea that endocytic trafficking is crucial in regulating receptor signaling and associated diseases. Specifically, strong evidence points to the involvement of sorting nexins (SNXs), particularly SNX...
Bioactivity, hemocompatibility, and inflammatory response of calcium incorporated sulfonated polyether ether ketone on mouse-derived bone marrow cells [0.03%]
生物相容性及抗炎性能的磺化聚醚醚酮钙离子释放材料的体外生物学评价
Shanmuga Sundar Saravanabhavan,Prabhu Narayanaswamy Venkatesan,Narendranath Jonna et al.
Shanmuga Sundar Saravanabhavan et al.
Natural and synthetic polymeric materials, particularly soft and hard tissue replacements, are paramount in medicine. We prepared calcium-incorporated sulfonated polyether-ether ketone (SPEEK) polymer membranes for bone applications. The bi...
Effect of exogenous γ-aminobutyric acid on physiological property, antioxidant activity, and cadmium uptake of quinoa seedlings under cadmium stress [0.03%]
外源γ-氨基丁酸对镉胁迫下藜幼苗生理特性、抗氧化能力和镉吸收的影响
Xiao Hua Hao,Ke Xin Liu,Meng Yuan Zhang
Xiao Hua Hao
Increasing cadmium (Cd) pollution has negative effects on quinoa growth and production. Gamma-aminobutyric acid (GABA) confers plants with stress resistance to heavy metals; however, the mechanism remains unclear. We explored the effects of...
Atox1-cyclin D1 loop activity is critical for survival of tumor cells with inactivated TP53 [0.03%]
ATX1-周期蛋白D1信号正反馈回路在TP53缺陷性肿瘤细胞存活中具有关键作用
Oleg A Kuchur,Sofya S Pogodaeva,Anna V Shcherbakova et al.
Oleg A Kuchur et al.
The search for relevant molecular targets is one of the main tasks of modern tumor chemotherapy. To successfully achieve this, it is necessary to have the most complete understanding of the functioning of a transcriptional apparatus of the ...
UCHL1-dependent control of hypoxia-inducible factor transcriptional activity during liver fibrosis [0.03%]
UCHL1在肝纤维化过程中调控缺氧诱导因子转录活性的作用机制研究
Amy Collins,Rebecca Scott,Caroline L Wilson et al.
Amy Collins et al.
Liver fibrosis is the excessive accumulation of extracellular matrix proteins that occurs in most types of chronic liver disease. At the cellular level, liver fibrosis is associated with the activation of hepatic stellate cells (HSCs) which...
Retraction: MicroRNA-223 decreases cell proliferation, migration, invasion and enhances cell apoptosis in childhood acute lymphoblastic leukemia via targeting Forkhead box O1 [0.03%]
撤稿：微小核糖核酸-223通过靶向叉头盒O1抑制儿童急性淋巴细胞白血病细胞增殖、迁移、侵袭并促进细胞凋亡
Retraction of Publication
Bioscience reports. 2024 May 29;44(5):BSR-2020-0485_RET. DOI:10.1042/BSR-2020-0485_RET 2024
Retraction: MicroRNA-26a reduces synovial inflammation and cartilage injury in osteoarthritis of knee joints through impairing the NF-κB signaling pathway [0.03%]
撤回：microRNA-26a通过破坏NF-κB信号通路减少膝关节骨关节炎滑膜炎症和软骨损伤
Retraction of Publication
Bioscience reports. 2024 May 29;44(5):BSR-2018-2025_RET. DOI:10.1042/BSR-2018-2025_RET 2024