Ginger Extract Promotes Pancreatic Islets Regeneration in Streptozotocin-Induced Diabetic Rats [0.03%]
姜提取物促进链脲佐菌素所致糖尿病大鼠胰岛再生
Manal S Abbood,Amani M Aladsani,Suzanne A Al-Bustan
Manal S Abbood
Ginger (Zingiber officinale) exerts an antidiabetic effect by restoring pancreatic β-cells. The present study aimed to investigate the mechanism by which ginger extract induces the regeneration of functional β-cells in diabetic rats. Spra...
Interferon-induced ADP-ribosylation: technical developments driving ICAB discovery [0.03%]
干扰素诱导的ADP核糖基化：技术发展推动ICAB的发现
Victoria Chaves Ribeiro,Lilian Cristina Russo,Dulce María González Duré et al.
Victoria Chaves Ribeiro et al.
Cells respond to a variety of internal and external stimuli by regulating the activities of different signalling cascades and cellular processes, often via chemical modifications of biological macromolecules that modulate their overall leve...
Dynamical organization of vimentin intermediate filaments in living cells revealed by MoNaLISA nanoscopy [0.03%]
利用MoNaLISA纳米显微镜技术揭示活细胞中波形蛋白中间丝的动态组织模式
Mariano Smoler,Francesca Pennacchietti,María Cecilia De Rossi et al.
Mariano Smoler et al.
Intermediate filaments are intimately involved in the mechanical behavior of cells. Unfortunately, the resolution of optical microscopy limits our understanding of their organization. Here, we combined nanoscopy, single-filament tracking, a...
Hydrogen Sulfide Attenuates Sepsis-Induced Cardiac Dysfunction in Infant Rats by Inhibiting the Expression of Cold-Inducible RNA-Binding Protein [0.03%]
氢硫化物通过抑制冷诱导RNA结合蛋白的表达来缓解脓毒症诱发的婴儿大鼠心功能障碍
Desi Li,Sheng Jin,Xu Teng et al.
Desi Li et al.
Sepsis-induced cardiac dysfunction is one of the most common complications of sepsis. It is also a major cause of death in pediatric intensive care units. The underlying mechanism of sepsis-induced cardiac dysfunction remains elusive. CIRP ...
Exploration of Vitamin D Hydroxy Metabolites C3 Epimers in Patients with Cardiovascular Disease: an observational study [0.03%]
心血管病患者体内维生素D羟基代谢产物C3差向异构体的探索性研究：一项观察性研究
Mohamed Abouzid,Łukasz Kruszyna,Julia Kerner et al.
Mohamed Abouzid et al.
Roughly 90% of the Polish population experiences vitamin D deficiency. The 3-epi-25(OH)D2 and 3-epi-25(OH)D3 are stereoisomers of 25(OH)D2 and 25(OH)D3, and they can inadvertently be included in measurements of 25(OH)D levels, potentially l...
Carbonyl Reductase 1: a novel regulator of blood pressure in Down Syndrome [0.03%]
下 syndrome血压表调节因子： Carbonyl Reductase 1
Alexandra Malbon,Alicja Czopek,Andrew Beekman et al.
Alexandra Malbon et al.
Approximately one in every 800 children is born with the severe aneuploid condition of Down Syndrome, a trisomy of chromosome 21. Low blood pressure (hypotension) is a common condition associated with DS and can have a significant impact on...
The fluoroquinolone compounds potentiate the antifungal activity of the echinocandins against Aspergillus fumigatus [0.03%]
氟喹诺酮类化合物可增强丙烯胺类抗真菌药对烟曲霉的抗菌活性
Jin-Ju Choi,Suzie Kang,Yoonseo Lee et al.
Jin-Ju Choi et al.
The antifungal drugs of the echinocandin family show high efficacy against Aspergillus fumigatus. However, their paradoxical effect, which restores fungal growth at high drug concentrations, and the emergence of resistant strains necessitat...
Structural analysis of genetic variants of the human tumor suppressor Palb2 coiled-coil domain [0.03%]
人肿瘤抑制因子PALB2卷曲螺旋结构域的基因变异结构分析
Pothula Purushotham Reddy,Apurva Phale,Ranabir Das
Pothula Purushotham Reddy
The tumor suppressor PALB2 is a key player in the Homologous Recombination (HR) pathway, functionally connecting BRCA proteins at the DNA damage site. PALB2 forms homodimers via its coiled-coil domain, and during HR, it forms a heterodimeri...
Electron transfer in multicentre redox proteins: from fundamentals to extracellular electron transfer [0.03%]
多中心红氧化还原蛋白中的电子转移：从基本原理到细胞外电子转移
Busra Bayar,Ricardo Soares,Haris Nalakath et al.
Busra Bayar et al.
Multicentre redox proteins participate in diverse metabolic processes, such as redox shuttling, multielectron catalysis, or long-distance electron conduction. The detail in which these processes can be analysed depends on the capacity of ex...
Palmitoylation and regulation of potassium dependent sodium/calcium exchangers (NCKX) [0.03%]
棕榈酰化及钾离子依赖性钠/钙交换蛋白(NCKX)的调节作用
Ran Tao,Alan D Robertson,William Fuller et al.
Ran Tao et al.
Cellular Ca2+ homeostasis is critical for normal cell physiology and is regulated by several mechanisms. Two major players in intracellular Ca2+ homeostasis in multiple tissues belong to SLC8 (Na+/Ca2+ exchangers (NCXs); NCX1-3) and SLC24 (...