CREB1-ROC1 axis drives bladder cancer progression under hypoxic conditions [0.03%]
缺氧条件下CREB1-ROC1轴驱动膀胱癌进展
Zhenchao Sun,Yingyu Wang,Shengjie You et al.
Zhenchao Sun et al.
Downregulation of miR-194-5p impairs cardiomyocyte proliferation and differentiation through targeting Fign in congenital heart disease [0.03%]
miR-194-5p下调通过靶向FIGN对先天性心脏病心肌细胞增殖和分化的抑制作用
Peishan Liang,Guangli Ren,Jie Zhu et al.
Peishan Liang et al.
From copper transport to cuproptosis: emerging therapeutic targets in cardiovascular disease [0.03%]
从铜转运到铜死亡：心血管疾病中新兴的治疗靶点
Xiaobing Zhang,Jiawen Liu,Cong He et al.
Xiaobing Zhang et al.
S-equol promotes ferroptosis in triple negative breast cancer by coordinating NCOA4-mediated ferritinophagy and PPARγ-mediated lipid metabolism [0.03%]
S-equol通过协调NCOA4介导的铁蛋白自噬和PPARγ介导的脂质代谢来促进三阴性乳腺癌中铁死亡的发展
Fubiao Ni,Ziyang Huang,Yuekai Cui et al.
Fubiao Ni et al.
Triple negative breast cancer (TNBC) is a diverse and highly aggressive cancer characterized by a strong tendency to metastasize, poor prognosis, and a lack of effective therapeutic targets. S-equol, an active metabolinte produced by gut mi...
Dexmedetomidine inhibits microglia activation, neuroinflammation, and glycolysis in postoperative cognitive dysfunction by promoting YTHDF2-mediated PKM2 mRNA degradation [0.03%]
右美托咪啶通过促进YTHDF2介导的PKM2mRNA降解抑制术后认知功能障碍小胶质细胞活化、神经炎症和糖酵解
Qianyu Li,Huiyue Wang,Nan Chen et al.
Qianyu Li et al.
Targeting PSAT1 in diabetic kidney disease: a ferroptosis-driven strategy for precision therapy [0.03%]
靶向PSAT1治疗糖尿病肾病：一种以铁死亡驱动的精准疗法策略
Yiling Wei,Cheng Yuan,Danqin Lu et al.
Yiling Wei et al.
CHI3L1: a novel regulator of vascular remodeling in pulmonary arterial hypertension [0.03%]
肺动脉高压中糖链蛋白CHI3L1对血管重塑的调节作用
Shuai Gao,Shuiyan Zhao,Yue Wang et al.
Shuai Gao et al.
USP52 impedes malignant progression and cell stemness in prostate cancer by deubiquitinating RBM5 to down-regulate NCAPG2 [0.03%]
USP52通过去泛素化RBM5来下调NCAPG2以抑制前列腺癌的恶性进展和细胞干性
Hongliang Wu,Sheng Wang,Shuai Yang et al.
Hongliang Wu et al.
Ubiquitin-specific protease 52 (USP52) is vital to cancer progression by mediating the deubiquitination; however, its biological role and mechanism in prostate cancer (PCa) remain unexplored. Herein, this study aimed to discover the functio...
A novel cuproptosis-related prognostic gene signature is identified by machine learning and integrative analyses in gliomas [0.03%]
机器学习和综合分析识别出胶质瘤中一种新的铜死亡相关的预后基因标志物
Jiangchun Ma,Weixian Liu,Xiaoyong Shi et al.
Jiangchun Ma et al.
Recent studies have highlighted the impact of copper-induced cell death (cuproptosis) on cancer progression, prognosis, and treatment, but it remains unclear whether cuproptosis-related genes (CRGs) play any role in the glioma tumor microen...