In Vitro and In Vivo Evaluation of the Antidiabetic Activity of Solidago virgaurea Extracts [0.03%]
欧洲金丝桃提取物的降糖活性的体内外评价研究
Syeda Andleeb Zehra,Prapanna Bhattarai,Jian Zhang et al.
Syeda Andleeb Zehra et al.
Background: Solidago virgaurea (Asteraceae) has been used for more than 700 years for treating cystitis, chronic nephritis, urolithiasis, rheumatism, and inflammatory diseases. However, the antidiabetic activity of Solida...
Antiplasmodial Compounds from Leaves of Dodonaea angustifolia [0.03%]
Dodonaea angustifolia叶子中的抗疟成分研究
Yadessa Melaku,Tefera Worku,Yemane Tadesse et al.
Yadessa Melaku et al.
Background: Dodonaea angustifolia is used in Ethiopian traditional medicine to treat malaria. The objective of this work was to conduct bioassay guided fractionation of the leaves of D. angustifolia using Plasmodium bergh...
Protodioscin, Isolated from the Rhizome of Dioscorea tokoro Collected in Northern Japan is the Major Antiproliferative Compound to HL-60 Leukemic Cells [0.03%]
日本北部地素巴戟连块根中分离到的拟大豆苷元是抗HL-60细胞的主要有效成分
Manami Oyama,Tetsuo Tokiwano,Satoru Kawaii et al.
Manami Oyama et al.
Background: The rhizome of Oni-dokoro (a wild yam, Dioscorea tokoro) has extremely bitter taste and is not generally regarded edible;, however, in northern part of Japan, such as Iwate and a part of Aomori, it is used as ...
Synthesis of ST7612AA1, a Novel Oral HDAC Inhibitor, via Radical Thioacetic Acid Addition [0.03%]
ST7612AA1的新口服型HDAC抑制剂的自由基硫乙酸加成合成法
Gianfranco Battistuzzi,Giuseppe Giannini
Gianfranco Battistuzzi
Abstract background: In the expanding field of anticancer drugs, HDAC inhibitors are playing an increasingly important role. To date, four/five HDAC inhibitors have been approved by FDA. All these compounds fit the widely...
Nanomedicine: Addressing Cardiovascular Disease and Cardiovascular Tissue Regeneration [0.03%]
纳米医学：应对心血管疾病和心血管组织再生
Rebekah A Neal,Olugbemisola Oredein-McCoy,Edward A Botchwey
Rebekah A Neal
Cardiovascular disease is becoming an increasingly significant problem. In attempts to overcome many of the traditional hurdles of cardiovascular disease treatment, therapeutic approaches have been gradually moving beyond an exclusive focus...
DNA Cleaving "Tandem-Array" Metallopeptides Activated With KHSO5: Towards the Development of Multi-Metallated Bioactive Conjugates and Compounds [0.03%]
二价金属螯合肽活化后能切断DNA：朝多金属修饰生物缀合物和化合物发展的一步
Mark A Lewis,Katie M Williams,Ya-Yin Fang et al.
Mark A Lewis et al.
Amino terminal peptides of the general form Gly-Gly-His have been used to introduce single sites of metal binding and redox activity into a wide range of biomolecules to create bioactive compounds and conjugates capable of substrate oxidati...
A Cell-Cell Communication Marker for Identifying Targeted Tumor Therapies [0.03%]
用于识别靶向肿瘤疗法的细胞间通讯标志物
Diane F Matesic,Amna Ali,Tatyana S Sidorova et al.
Diane F Matesic et al.
Cell-cell communication through gap junctions is aberrant or absent in a majority of human cancer cells, compared to cells in corresponding normal tissues. This and other evidence has led to the hypothesis that gap junction channels, compri...
Comparison of Artemisia annua Bioactivities between Traditional Medicine and Chemical Extracts [0.03%]
传统医药与化学提取物的青蒿生物活性比较研究
Ahmed Nageeb,Azza Al-Tawashi,Abdul-Hamid Mohammad Emwas et al.
Ahmed Nageeb et al.
The present work investigates the efficacy of using Artemisia annua in traditional medicine in comparison with chemical extracts of its bioactive molecules. In addition, the effects of location (Egypt and Jericho) on the bioactivities of th...
Wen-Hui Xu,Xing-Cong Li
Wen-Hui Xu
This review documents chemical structures and antifungal activities of 68 compounds isolated from 22 Piper species of the plant family Piperaceae. These compounds include amides, flavonoids, prenylated benzoic acid derivatives, lignans, phe...
Effect of Soil Nutrient on Production and Diversity of Volatile Terpenoids from Plants [0.03%]
土壤养分对植物挥发性倍半萜的产量和多样性的影响
E Ormeño,C Fernandez
E Ormeño
Terpenoid production (emission and storage) within foliage plays direct and indirect defensive and protective functions for the plant, mediates complex trophic relationships and controls the oxidation capacity of the atmosphere. Both biotic...