Jason S Stumhofer,P&#x;ng Loke
Jason S Stumhofer
Parasitic diseases caused by helminth and protozoan infections remain one of the largest global public health problems for mankind. While natural immunity in man is rare or slow to develop for many parasites, the immune response is capable ...
Lingli Dong,Yu Chen,Yasufumi Masaki et al.
Lingli Dong et al.
Primary Sjögren's syndrome (pSS) is a systemic as well as an organ-specific autoimmune disease characterized by lymphocytic infiltration of the glandular epithelial tissue. SS patients have been reported to be at highest risk of developing...
Innate Immunity and the Role of Epithelial Barrier During Aspergillus fumigatus Infection [0.03%]
固有免疫及表皮屏障在烟曲霉感染中的作用
Elena Svirshchevskaya,Dmitrii Zubkov,Isabelle Mouyna et al.
Elena Svirshchevskaya et al.
Fungi are the most important eukaryotic infective agents in Europe which largely overpass parasite infections. Total number of people dying of fungal infection is increasing and this trend is likely to continue due to the increase in immuno...
Jerry Y Niederkorn
Jerry Y Niederkorn
The ocular surface is continuously exposed to environmental agents such as allergens, pollutants, and microorganisms, which could provoke inflammation. However, an array of anatomical, physiological, and immunological features of the ocular...
Shegufta Mahbub,Aleah L Brubaker,Elizabeth J Kovacs
Shegufta Mahbub
The relationship between advanced age and immunologic deficits is becoming an area of rapidly advancing research. Many of the clinical hurdles in the elderly population result from dysregulation of the immune system leading to the inability...
Immunological regulation of the central nervous system: From physiological to pathological processes [0.03%]
中枢神经系统的免疫调节：从生理过程到病理过程
Oscar Gonzalez-Perez
Oscar Gonzalez-Perez
Brian E Leonard
Brian E Leonard
Chronic stress, by initiating changes in the hypothalamic-pituitary-adrenal axis and the immune system, acts as a trigger for anxiety and depression. Both experimental and clinical evidence shows that a rise in the concentrations of proinfl...
Norbert Müller,Markus J Schwarz
Norbert Müller
Although an immune dysfunction and the involvement of infectious agents in the pathophysiology of schizophrenia are discussed since decades, the field never came into the mainstream of research. In schizophrenia a blunted type-1 immune resp...
Interleukin-12: an update on its immunological activities, signaling and regulation of gene expression [0.03%]
白细胞介素12的研究新进展：免疫学活性、信号传导及基因表达调控
Jianguo Liu,Shanjin Cao,Sunjung Kim et al.
Jianguo Liu et al.
Interleukin-12 (IL-12) is a heterodimeric cytokine composed of the p35 and p40 subunits. It is produced by antigen-presenting cells and plays a critical role in host defense against intracellular microbial infection and control of malignanc...
Oscar Gonzalez-Perez,Fernando Jauregui-Huerta,Alma Yadira Galvez-Contreras
Oscar Gonzalez-Perez
New neurons are continuously produced in most, if not all, mammals. This Neurogenesis occurs only in discrete regions of the adult brain: the subventricular zone (SVZ) and the subgranular zone (SGZ). In these areas, there are neural stem ce...