Implementing a central composite design for the optimization of solid phase microextraction to establish the urinary volatomic expression: a first approach for breast cancer [0.03%]
实现中心组合设计优化固相微萃取法建立尿液挥发性标记物表达谱：乳腺癌检测初步尝试
Catarina L Silva,Rosa Perestrelo,Pedro Silva et al.
Catarina L Silva et al.
Introduction: Breast cancer (BC) is positioned as the second among all cancers remaining at the top of women´s diseases worldwide followed by colorectum, lung, cervix, and thyroid cancers. The main drawback of most the s...
Two data pre-processing workflows to facilitate the discovery of biomarkers by 2D NMR metabolomics [0.03%]
两种数据预处理 workflow 以促进基于二维核磁共振代谢组学的生物标志物发现
Baptiste Féraud,Justine Leenders,Estelle Martineau et al.
Baptiste Féraud et al.
Introduction: The pre-processing of analytical data in metabolomics must be considered as a whole to allow the construction of a global and unique object for any further simultaneous data analysis or multivariate statisti...
Comparative metabolomics analysis of different resistant rice varieties in response to the brown planthopper Nilaparvata lugens Hemiptera: Delphacidae [0.03%]
不同抗性水稻品种对褐飞虱响应的比较代谢组学分析
Kui Kang,Lei Yue,Xin Xia et al.
Kui Kang et al.
Introduction: The brown planthopper (BPH, Nilaparvata lugens Stål, Hemiptera: Delphacidae) is one of the most devastating insect pests of the crucially important cereal crop, rice (Oryza sativa L.). Currently, multiple B...
Correction to: Metabolomic richness and fingerprints of deep-sea coral species and populations [0.03%]
Correction to: 深海珊瑚种类和种群的代谢组丰富度和指纹图案
Samuel A Vohsen,Charles R Fisher,Iliana B Baums
Samuel A Vohsen
The article "Metabolomic richness and fingerprints of deep-sea coral species and populations", written by Samuel A. Vohsen, Charles R. Fisher and Iliana B. Baums, was originally published electronically on the publisher's internet portal (c...
Exposure to disinfection byproducts and risk of type 2 diabetes: a nested case-control study in the HUNT and Lifelines cohorts [0.03%]
消毒副产物与2型糖尿病风险的关系：HUNT和Lifelines队列中的病例对照研究
Stephanie Gängler,Melanie Waldenberger,Anna Artati et al.
Stephanie Gängler et al.
Introduction: Environmental chemicals acting as metabolic disruptors have been implicated with diabetogenesis, but evidence is weak among short-lived chemicals, such as disinfection byproducts (trihalomethanes, THM compos...
Untargeted LC-MS metabolomic studies of Asteraceae species to discover inhibitors of Leishmania major dihydroorotate dehydrogenase [0.03%]
利用未靶向LC-MS代谢组学方法研究菊科植物中沙氏利什曼原虫二氢乳清酸脱氢酶抑制剂的作用机制
Lucas A Chibli,Annylory L Rosa,Maria Cristina Nonato et al.
Lucas A Chibli et al.
Introduction: Interesting data about the family Asteraceae as a new source of Leishmania major dihydroorotate dehydrogenase (LmDHODH) inhibitors are presented. This key macromolecular target for parasites causing neglecte...
Metabolomic study of polyamines in rat urine following intraperitoneal injection of γ-hydroxybutyric acid [0.03%]
γ-羟基丁酸腹腔注射后大鼠尿液聚胺的代谢组学研究
Hyeon-Seong Lee,Chan Seo,Young-A Kim et al.
Hyeon-Seong Lee et al.
Introduction: Recently, illegal abuse of γ-hydroxybutyric acid (GHB) has increased in drug-facilitated crimes, but the determination of GHB exposure and intoxication is difficult due to rapid metabolism of GHB. Its bioch...
Disturbed energy and amino acid metabolism with their diagnostic potential in mitral valve disease revealed by untargeted plasma metabolic profiling [0.03%]
基于非靶向血浆代谢组学的二尖瓣病变患者能量及氨基酸代谢紊乱与诊断价值研究
Limiao Jiang,Jing Wang,Rui Li et al.
Limiao Jiang et al.
Introduction: Mitral valve disease (MVD), including mitral valve regurgitation (MR) and mitral valve stenosis (MS), is a chronic and progressive cardiac malady. However, the metabolic alterations in MVD is not well-unders...
Metabolomic characterization of sunflower leaf allows discriminating genotype groups or stress levels with a minimal set of metabolic markers [0.03%]
基于最小代谢标记的向日葵叶片代谢组表征用于区分基因型类群或胁迫水平
Olivier Fernandez,Maria Urrutia,Thierry Berton et al.
Olivier Fernandez et al.
Introduction: Plant and crop metabolomic analyses may be used to study metabolism across genetic and environmental diversity. Complementary analytical strategies are useful for investigating metabolic changes and searchin...
Metabolic signatures suggest o-phosphocholine to UDP-N-acetylglucosamine ratio as a potential biomarker for high-glucose and/or palmitate exposure in pancreatic β-cells [0.03%]
代谢标志物提示o-磷胆碱与UDP-N-乙酰葡萄糖胺比率是高葡萄糖和/或棕榈酸暴露于胰岛β细胞的潜在生物标志物
Saleem Yousf,Devika M Sardesai,Abraham B Mathew et al.
Saleem Yousf et al.
Introduction: Chronic exposure to high-glucose and free fatty acids (FFA) alone/or in combination; and the resulting gluco-, lipo- and glucolipo-toxic conditions, respectively, have been known to induce dysfunction and ap...