Recognition of early and late stages of bladder cancer using metabolites and machine learning [0.03%]
基于代谢物和机器学习的膀胱癌早晚期识别
Valentina L Kouznetsova,Elliot Kim,Eden L Romm et al.
Valentina L Kouznetsova et al.
Introduction: Bladder cancer (BCa) is one of the most common and aggressive cancers. It is the sixth most frequently occurring cancer in men and its rate of occurrence increases with age. The current method of BCa diagnos...
Are we close to defining a metabolomic signature of human obesity? A systematic review of metabolomics studies [0.03%]
定义人类肥胖代谢标志物接近吗？代谢组学研究的系统评价
Oscar Daniel Rangel-Huerta,Belén Pastor-Villaescusa,Angel Gil
Oscar Daniel Rangel-Huerta
Introduction: Obesity is a disorder characterized by a disproportionate increase in body weight in relation to height, mainly due to the accumulation of fat, and is considered a pandemic of the present century by many int...
Influence of environmental factors on the volatile composition of two Brazilian medicinal plants: Mikania laevigata and Mikania glomerata [0.03%]
环境因素对两种巴西药用植物迈克尼亞_laevigata_和迈克尼亞_glomerata_挥发油成分的影响分析
Vanessa Ayumi Ueno,Alexandra Christine Helena Frankland Sawaya
Vanessa Ayumi Ueno
Introduction: Mikania laevigata Sch.Bip. ex Baker and Mikania glomerata Spreng. are medicinal plants popularly known as guaco, used for inflammatory diseases of the respiratory system, included in pharmaceutical formulari...
Impact of sample preparation upon intracellular metabolite measurements in 3D cell culture systems [0.03%]
样品制备对三维细胞培养系统中细胞内代谢物测量的影响
Caroline Mathon,David Bovard,Quentin Dutertre et al.
Caroline Mathon et al.
Introduction: Interest in cell culture metabolomics has increased greatly in recent years because of its many potential applications and advantages (e.g., in toxicology). The first critical step for exploring the cellular...
A metabolomic signature of treated and drug-naïve patients with Parkinson's disease: a pilot study [0.03%]
帕金森病患者治疗和未治疗患者的代谢标志物：一项初步研究
Jacopo Troisi,Annamaria Landolfi,Carmine Vitale et al.
Jacopo Troisi et al.
Introduction: About 90% of cases of Parkinson's disease (PD) are idiopathic and attempts to understand pathogenesis typically assume a multifactorial origin. Multifactorial diseases can be studied using metabolomics, sinc...
NMR metabolomics identifies over 60 biomarkers associated with Type II Diabetes impairment in db/db mice [0.03%]
基于db/db小鼠的I型糖尿病损伤的核磁共振代谢组学研究发现超过60种生物标志物
Marina Mora-Ortiz,Patricia Nuñez Ramos,Alain Oregioni et al.
Marina Mora-Ortiz et al.
Introduction: The rapid expansion of Type 2 Diabetes (T2D), that currently affects 90% of people suffering from diabetes, urges us to develop a better understanding of the metabolic processes involved in the disease proce...
Metabolomic profile of diet-induced obesity mice in response to humanin and small humanin-like peptide 2 treatment [0.03%]
人源蛋白humanin和mini-humanin干预诱导肥胖小鼠的代谢组学研究
Hemal H Mehta,Jialin Xiao,Ricardo Ramirez et al.
Hemal H Mehta et al.
Introduction: The mitochondrial-derived peptides (MDPs) are a novel group of natural occurring peptides that have important signaling functions and biological activity. Both humanin and small-humanin-like peptide 2 (SHLP2...
Metabolomic signatures of asthma-COPD overlap (ACO) are different from asthma and COPD [0.03%]
哮喘-COPD重叠（ACO）的代谢标志与哮喘和COPD不同
Nilanjana Ghosh,Priyanka Choudhury,Elavarasan Subramani et al.
Nilanjana Ghosh et al.
Introduction: Asthma-chronic obstructive pulmonary disease (COPD) overlap, termed as ACO, is a complex heterogeneous disease without any clear diagnostic or therapeutic guidelines. The pathophysiology of the disease, its ...
Metabolomics identifies serum and exosomes metabolite markers of pancreatic cancer [0.03%]
代谢组学识别胰腺癌的血清和外泌体代谢标志物
Lianyuan Tao,Juntuo Zhou,Chunhui Yuan et al.
Lianyuan Tao et al.
Introduction: Pancreatic cancer (PC) is one of the most aggressive malignancies, and it's difficult to diagnosis PC at an early stage, which leads to the poor prognosis of PC. ...
Integrated metabolomics identifies CYP72A67 and CYP72A68 oxidases in the biosynthesis of Medicago truncatula oleanate sapogenins [0.03%]
整合代谢组学鉴定出CYP72A67和CYP72A68氧化酶在狭叶三裂叶鼠李皂苷生物合成中的作用
Vered Tzin,John H Snyder,Dong Sik Yang et al.
Vered Tzin et al.
Introduction: Triterpene saponins are important bioactive plant natural products found in many plant families including the Leguminosae. Objectives: ...