Metabolomic profiling and vitamin D pathway investigation in diabetic foot ulcer patients [0.03%]
糖尿病足溃疡患者代谢轮廓及维生素D通路研究
Remya Reveendran,Sreelathakumari Krishnan Thankam,Adbul Jaleel et al.
Remya Reveendran et al.
Introduction: Diabetic foot ulcer (DFU) is a severe complication of diabetes mellitus (DM) characterized by chronic inflammation, impaired wound repair, and systemic metabolic imbalance. This study aimed to identify plasm...
Scanning central carbon metabolism: a HILIC-HR-TOF-MS metabolome method [0.03%]
采用HILIC-HR-TOF-MS代谢组方法扫描中心碳代谢
Victoria Pozo Garcia,Valentina Ferro,Jolene Rier et al.
Victoria Pozo Garcia et al.
Introduction: Central carbon metabolism (CCM) is the primary metabolic hub of the cell, governing energy production and providing precursors essential for a myriad of biosynthetic pathways. Developing analytical tools tha...
Obesity is associated with distinct oxylipins in heart failure with preserved ejection fraction [0.03%]
肥胖与射血分数保留型心力衰竭中的特定氧脂质相关
Ashish Yadav,Sareeta Manandhar,Alex Kloster et al.
Ashish Yadav et al.
Background: Heart failure with preserved ejection fraction (HFpEF) accounts for nearly half of heart failure cases, with obesity emerging as a key pathophysiologic driver. Oxylipins are lipid signaling molecules linked to...
Lipidomic profile of meningiomas harboring different NF2 mutation status [0.03%]
不同NF2突变状态脑膜瘤的脂质组学谱型分析
Joanna Bogusiewicz,Ivana Stanimirova,Magdalena Gaca-Tabaszewska et al.
Joanna Bogusiewicz et al.
Introduction: Meningiomas are mainly benign brain tumors, but they can evolve to higher grades. The phenomena of these changes are not well-known. Therefore, more basic research is needed. This study attempted to assess t...
Metabolomic and lipidomic plasma profiles according to metabolic dysfunction-associated steatotic liver diseases (MASLD) stages in the absence of type 2 diabetes (T2D) [0.03%]
无2型糖尿病(T2D)代谢功能障碍相关肝脂质沉积疾病(MASLD)各期的代谢组和脂质组图谱
Marion Pradeau,Julie-Catherine Coll,Ana Berteaux et al.
Marion Pradeau et al.
Introduction: Amino acids (AAs), tricarboxylic acid (TCA) cycle intermediates, and acylcarnitines (ACs) can reflect energetic metabolism. Metabolic dysfunction-associated steatotic liver (MASLD) has been associated with t...
Deciphering the circulating lipidome signature associated with physical performance in gastric cancer patients: an exploratory study [0.03%]
胃癌患者体能表现相关循环脂质组特征的探索性研究
Ana Carolina Pinto,Helena Beatriz Ferreira,Samuel Barbosa et al.
Ana Carolina Pinto et al.
Introduction: Physical performance strongly influences peri-treatment outcomes in gastric cancer (GC), yet simple molecular markers reflecting functional status are lacking. Lipidomics may help identify circulating biomar...
Seasonality and fruiting converge on megastigmanes to shape foliar metabolic plasticity in Miconia albicans (Swartz) Triana (Melastomataceae) [0.03%]
季节性和结果作用于巨裂脂烷以塑造Miconia albicans（Swartz）Triana（野牡丹科）的叶片代谢可塑性
André Nunes Silva,Djaceli Sampaio de Oliveira Dembogurski,Amanda Galdi Boaretto et al.
André Nunes Silva et al.
Introduction: Miconia albicans is a medicinal plant widely used in traditional medicine and represents a promising candidate for phytotherapeutic drug development. Despite its widespread use, the influence of environmenta...
ILDMDB: a manually curated database of metabolite-disease associations in interstitial lung diseases [0.03%]
ILDMDM数据库：间质性肺疾病中代谢物-疾病的关联的手工整理库
Yaowu He,Yupeng Li,Jing Geng et al.
Yaowu He et al.
Introduction: Metabolomics analysis shows great promise in identifying non-invasive biomarkers for interstitial lung diseases (ILDs). However, the relevant data are scattered across numerous disparate publications, hinder...
Integrated metabolomic profiling reveals metabolomic responses by epicardial and myocardial stromal cells to ischemia [0.03%]
整合代谢组学分析揭示心外膜和心肌间质细胞缺血反应中的代谢重编程
Dongwei Sun,Alex Postajian,Edgmin Rostomian et al.
Dongwei Sun et al.
Introduction: Cardiac ischemia induces substantial metabolomic reprogramming, which dysregulates cardiomyocytes (CMs) and non-myocyte stromal cell populations. The stromal cells derived from epicardial adipose tissue (EAT...
The essential role of hydrogen gas recycling by gut microbes in reducing deuterium load in host mitochondria: is trimethylamine oxide a deuterium sensor? [0.03%]
肠道微生物介导的氢气循环在减少宿主线粒体密度的负荷方面的作用：胆氧化是否为一种脱水器传感器？
Stephanie Seneff,László G Boros
Stephanie Seneff
Background: The human gut microbiome plays many essential roles, but an often-overlooked role is to maintain an abundant supply of deuterium depleted (deupleted) nutrients to fuel the host mitochondria. Excess deuterium (...