Lipidomics of longer-term effects in the murine model after exposure to mixed field radiation and combined infection [0.03%]
混合辐射和联合感染暴露后小鼠模型长期脂质组学效应研究
Evan L Pannkuk,Anika Kot,Lorreta Yun-Tien Lin et al.
Evan L Pannkuk et al.
Background: Accurate biodosimetry is essential for medical response during nuclear emergencies. However, mixed-field radiation and secondary infections create significant diagnostic challenges. ...
Evaluation of metabolite biomarker candidates in detecting HCC in patients with liver cirrhosis [0.03%]
评估代谢物生物标志物候选者在肝硬化患者中检测HCC的能力
Md Mamunur Rashid,Rency S Varghese,Muhammad Salman Sajid et al.
Md Mamunur Rashid et al.
Introduction: Hepatocellular carcinoma (HCC), the most prevalent form of liver cancer, ranks as the third leading cause of mortality globally. Patients diagnosed with HCC exhibit a dismal prognosis, mostly due to the emer...
Metabolic pathways associated with cardiometabolic risk effects on cognition in middle-aged adults: the CARDIA study [0.03%]
中年成人代谢途径与心元风险对认知的影响：CARDIA研究
Sujin Kang,Timothy Ebbels,Queenie Chan et al.
Sujin Kang et al.
Background: Evidence increasingly suggests a connection between cardiovascular disease and brain health in later life; however, the mechanistic pathways from human studies remain unclear. This study aimed to investigate w...
Lipidomic predictors of residual insulin production in adults with newly diagnosed type 1 diabetes [0.03%]
新发1型糖尿病成人残存胰岛素分泌的脂质组预测因素研究
Pernille Emilie Hostrup,Karolina Sulek,Flemming Pociot
Pernille Emilie Hostrup
Introduction: Alterations in the lipidomic profile have been implicated in the development and disease progression in type 1 diabetes. We have previously demonstrated that the lipidomic profile at the time of diagnosis co...
Characterization of multi-stage metabolic alterations in hepatitis B virus-related acute-on-chronic liver failure using high-coverage metabolomics [0.03%]
基于高覆盖代谢组学的乙型肝炎病毒相关急性-on-慢性肝功能衰竭多阶段代谢改变特征分析
Zhehua Zhang,He Jiang,Guoqi Zhang et al.
Zhehua Zhang et al.
Introduction: Hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) is a serious condition characterized by acute liver decompensation and multiple organ failure, which leads to high short-term mortality rat...
Urinary organic acid levels and their associations with clinical characteristics in patients with schizophrenia [0.03%]
精神分裂症患者尿有机酸水平及其临床特征相关性研究
Yavuz Yılmaz,Halef Okan Doğan,Ayşegül Murat et al.
Yavuz Yılmaz et al.
Introduction: Schizophrenia is a chronic psychiatric disorder characterized by substantial biological and clinical heterogeneity. Beyond classical neurotransmitter-based models, increasing evidence suggests that systemic ...
Metabolomic characterization and temporal dynamics of Burkholderia cepacia for polyhydroxyalkanoates production from oleic acid [0.03%]
以油酸为底物生产聚羟基脂肪酸酯的Burkholderiacepacia代谢组学表征及时空动态分析
Alfonso E Alarcón,Nubia C Moreno,Daniel Pardo-Rodriguez et al.
Alfonso E Alarcón et al.
Background: Polyhydroxyalkanoates (PHA) have become biodegradable alternatives for replacing chemical polymers. However, high production costs remain the primary obstacle to the commercial application of this bioprocess, ...
Metabolomic insights into inter-familial and pre-transport treatment effects on live transport stress in selectively-bred mussels, Perna canaliculus [0.03%]
关于选择性养殖绿盘鲍(Perna canaliculus)活体运输压力的科内个体间及运输前处理效应的代谢组学见解
M C F Cheng,L N Zamora,N J Delorme et al.
M C F Cheng et al.
Introduction: Selectively-bred green-lipped mussel, Perna canaliculus, families may differ in their physiological responses, potentially altering their sensitivity to preparatory treatment and thereby influencing its effe...
Metabolomics reveal drought-stress responses in guayule, a semi-arid rubber crop [0.03%]
代谢组学揭示半干旱橡胶作物乳胶树的干旱胁迫响应
Huy Phan,Hussein Abdel-Haleem
Huy Phan
Introduction: Natural rubber is crucial for many industries, and guayule, (Parthenium argentatum A. Gray, is a promising alternative source for rubber in the arid and semi-arid regions. Rubber concentration production in ...
Longitudinal fecal amino acid profiles in extremely preterm infants: early-life determinants and associations with late-onset sepsis [0.03%]
极早早产儿纵向粪便氨基酸谱特征及其早期生命决定因素和晚发性感染的关联研究
A J van Wesemael,R R de Kroon,N M Frerichs et al.
A J van Wesemael et al.
Introduction: Fecal microbiome and metabolome alterations precede late-onset sepsis (LOS) in preterm infants, but clinical determinants of fecal amino acid (AA) composition and association with LOS development remain poor...