Identifying sex-linked metabolomic biomarkers in fish gonads after bacterial infection [0.03%]
细菌感染对鱼类性腺代谢产物的影响及性别差异分析
M Caballero-Huertas,C Ladisa,S López-Chillarón et al.
M Caballero-Huertas et al.
Purpose: Fish aquaculture faces sustainable production challenges. Among them are the pathogenic outbreaks that can compromise the health of the stocks from various perspectives, including broodstock reproduction. This st...
Phenotypic and metabonomics studies of FMOs in C. elegans and their roles in lifespan extension [0.03%]
利用线虫研究FMOs的表型和代谢组学及其在寿命延长中的作用
Mohamed Said,Rafael Freire,Filipe Cabreiro et al.
Mohamed Said et al.
Introduction: Flavin-Containing Monooxygenases (FMO) are widely conserved, xenobiotic-detoxifying enzymes whose additional endogenous functions have been revealed in recent studies. Those roles include the regulation of l...
PMI estimation through 1H NMR metabolomics on human pericardial fluid: a validation study [0.03%]
通过人浆液性心包液~(1)H-NMR代谢组学进行PMI鉴定的验证研究
Alberto Chighine,Matteo Stocchero,Fabio De-Giorgio et al.
Alberto Chighine et al.
This study builds on a prior proof-of-concept metabolomic analysis of post-mortem pericardial fluid to assess its reproducibility and validate its utility for estimating the post-mortem interval. Sixty-five pericardial fluid samples were co...
Influence of climatic conditions on metabolite production in some Himalayan plants: a literature review [0.03%]
气候条件对某些喜马拉雅植物次生代谢产物的影响：文献综述
Sugandh Singh,Mohd Ikram,Prakash Chand Sharma
Sugandh Singh
Plants of the Himalayan region produce a wide spectrum of metabolites whose abundance is strongly influenced by species identity, genotype, developmental stage, and environmental factors such as altitude and temperature. These metabolites a...
Proteomic and metabolomic profiling of plasma reveals physiologic changes in patients with convalescent COVID-19 [0.03%]
蛋白组学和代谢组学分析揭示了康复期新冠患者的生理变化
Lei Wang,Ying Zhang,Lixin Bao et al.
Lei Wang et al.
Background: This study aimed to analyze the molecular composition and physiological changes in the plasma of patients with convalescent coronavirus disease 2019 (COVID-19). ...
Chemometrics-guided plasma lipidomics insights underlying the decrease of plasma total cholesterol and LDLc in children with hypercholesterolemia following habitual intake of an EVOO-based phytosterols-enriched spreadable cream [0.03%]
化学计量学引导的血浆脂质组学见解：基于特级初榨橄榄油的植物甾醇丰富涂抹酱的习惯性摄入可降低高胆固醇儿童血浆总胆固醇和LDL-c水平
Pascual García-Pérez,Alejandra Vázquez-Aguilar,Estefanía Sánchez-Rodríguez et al.
Pascual García-Pérez et al.
Background: Higher LDL cholesterol levels are associated with increased risk of cardiovascular disease, and early intervention in children and regular follow-up are keystones for its prevention. Hypercholesterolemia can b...
Randomized Controlled Trial
Metabolomics : Official journal of the Metabolomic Society. 2025 Nov 15;21(6):169. DOI:10.1007/s11306-025-02368-3 2025
Mycobacterium tuberculosis curli pili (MTP) facilitates pathogenicity by modulating oxidative phosphorylation and carbon flux during early infection of A549 epithelial cells [0.03%]
麻风分枝杆菌.curli丝毛（MTP）通过调节A549上皮细胞早期感染过程中的氧化磷酸化和碳通量来促进致病性
Tarien J Naidoo,Shinese Ashokcoomar,Barry Truebody et al.
Tarien J Naidoo et al.
Background: The Mycobacterium tuberculosis (Mtb) curli pili (MTP) adhesin has been reported as a significant target for TB diagnostic and intervention strategies. The precise contribution of MTP in modulating oxidative ph...
Analytical practices, use and needs of standard and reference materials in the German-speaking metabolomics community: results of an online survey [0.03%]
德国讲德语的代谢组学社团中标准物质和参考材料的分析方法、使用及需求现状：一项在线调查的结果
Carsten Jaeger,Jutta Lintelmann,Raimo Franke et al.
Carsten Jaeger et al.
Introduction: Since the early 2000s, metabolomics has grown rapidly, becoming integral to fields like life sciences, health, and environmental research. This expansion has led to the formation of national and internationa...
Bioactive compound identification without fractionation: an Ocimum spp. case study [0.03%]
无需组分分离的生物活性成分鉴定研究——以罗勒属植物为例分析抗氧化和α-葡萄糖苷酶抑制剂化合物
Evelyn J Abraham,Kelsey Custer,R Teal Jordan et al.
Evelyn J Abraham et al.
Introduction: Identifying the phytochemistry underpinning a plant's observed therapeutic benefits is essential for understanding mechanisms of action and developing novel therapeutics. More recent efforts fusing global me...
Multi-marker discovery for mild cognitive impairment in metabolomics using machine learning with a global surrogate model via partial least squares [0.03%]
基于偏最小二乘全局代理模型的机器学习在代谢组学中寻找轻度认知障碍多标志物的研究
Yota Tatara,Hiroyuki Yamamoto,Kozue Terai et al.
Yota Tatara et al.
Introduction: Dementia can be prevented through early intervention; hence, there is an urgent need for biomarkers to help diagnose mild cognitive impairment (MCI). ...