GC-MS metabolic profiling reveals fructose-2,6-bisphosphate regulates branched chain amino acid metabolism in the heart during fasting [0.03%]
基于GC-MS代谢谱分析的果糖-2,6-二磷酸在饥饿条件下调节心肌支链氨基酸代谢的作用
Albert Batushansky,Satoshi Matsuzaki,Maria F Newhardt et al.
Albert Batushansky et al.
Introduction: As an insulin sensitive tissue, the heart decreases glucose usage during fasting. This response is mediated, in part, by decreasing phosphofructokinase-2 (PFK-2) activity and levels of its product fructose-2...
Ursodeoxycholic acid exerts hepatoprotective effects by regulating amino acid, flavonoid, and fatty acid metabolic pathways [0.03%]
鹅去氧胆酸通过调节氨基酸、黄酮和脂肪酸代谢途径发挥肝保护作用
Da Jung Kim,Hyewon Chung,Sang Chun Ji et al.
Da Jung Kim et al.
Introduction: Ursodeoxycholic acid (UDCA) is an intestinal bacterial metabolite with hepatoprotective effects. However, molecular mechanisms underlying its effects remain unclear. ...
Randomized Controlled Trial
Metabolomics : Official journal of the Metabolomic Society. 2019 Feb 27;15(3):30. DOI:10.1007/s11306-019-1494-5 2019
Elevated CO2 and virus infection impacts wheat and aphid metabolism [0.03%]
Elevated CO2和病毒感染影响小麦和蚜虫的代谢
Simone Vassiliadis,Kim M Plummer,Kevin S Powell et al.
Simone Vassiliadis et al.
Introduction: The aphid Rhopalosiphum padi L. is a vector of Barley yellow dwarf virus (BYDV) in wheat and other economically important cereal crops. Increased atmospheric CO2 has been shown to alter plant growth and meta...
Metabolomic richness and fingerprints of deep-sea coral species and populations [0.03%]
深海珊瑚种类和种群的代谢丰富度和指纹图案
Samuel A Vohsen,Charles R Fisher,Iliana B Baums
Samuel A Vohsen
Introduction: From shallow water to the deep sea, corals form the basis of diverse communities with significant ecological and economic value. These communities face many anthropogenic stressors including energy and miner...
Nitrogen deprivation in Fusarium oxysporum promotes mycotoxin production via intermediates in the Krebs cycle and unreported methylmalonyl-CoA mutase activity [0.03%]
氮缺乏通过三羧酸循环中间体和未报道的甲基烯丙酰辅酶a异构酶活性促进尖镰孢菌产毒
A V Karpe,M S Dunn,M C Taylor et al.
A V Karpe et al.
Introduction: Fusarium oxysporum has a high affinity for lignin and cellulose-based substrates and is known to grow in a wide range of environments. It is these properties and its ability to produce mycotoxins that have c...
Metabolomic and lipidomic assessment of the metabolic syndrome in Dutch middle-aged individuals reveals novel biological signatures separating health and disease [0.03%]
代谢组学和脂质组学评估荷兰中年人的代谢综合征发现新的生物标志物分离健康与疾病
Izabella Surowiec,Raymond Noordam,Kate Bennett et al.
Izabella Surowiec et al.
Background: We aimed to identify novel metabolite and lipid signatures connected with the metabolic syndrome in a Dutch middle-aged population. Methods: ...
Characterizing alternative feeds for rainbow trout (O. mykiss) by 1H NMR metabolomics [0.03%]
利用核磁共振代谢组学表征虹鳟(O.mykiss)的替代饲料
Simon Roques,Catherine Deborde,Nadège Richard et al.
Simon Roques et al.
Introduction: Fish feed formulations are constantly evolving to improve the quality of diets for farmed fish and to ensure the sustainability of the aquaculture sector. Nowadays, insect, microalgae and yeast are feedstuff...
Towards quality assurance and quality control in untargeted metabolomics studies [0.03%]
无目标代谢组学研究中的质量保证和质量控制
Richard D Beger,Warwick B Dunn,Abbas Bandukwala et al.
Richard D Beger et al.
We describe here the agreed upon first development steps and priority objectives of a community engagement effort to address current challenges in quality assurance (QA) and quality control (QC) in untargeted metabolomic studies. This has i...
Identification of antiplasmodial triterpenes from Keetia species using NMR-based metabolic profiling [0.03%]
基于NMR代谢轮廓的KEETIA属抗疟原虫三萜类成分的识别
Rafael Teixeira Freire,Joanne Bero,Claire Beaufay et al.
Rafael Teixeira Freire et al.
Introduction: The increase in multidrug resistance and lack of efficacy in malaria therapy has propelled the urgent discovery of new antiplasmodial drugs, reviving the screening of secondary metabolites from traditional m...
Phenolic variation among Chamaecrista nictitans subspecies and varieties revealed through UPLC-ESI(-)-MS/MS chemical fingerprinting [0.03%]
基于UPLC-ESI(-)-MS/MS化学指纹图谱的钩刺肠子草不同亚种和变种中苯酚类成分差异性分析
Luis Quirós-Guerrero,Federico Albertazzi,Emanuel Araya-Valverde et al.
Luis Quirós-Guerrero et al.
Introduction: Comparative analysis of metabolic features of plants has a high potential for determination of quality control of active ingredients, ecological or chemotaxonomic purposes. Specifically, the development of e...