Yukun Li,Raji Balasubramanian,D Bradley Welling et al.
Yukun Li et al.
Background: Disabling hearing loss affects millions of adults world-wide. Metabolomics investigations are comprehensive assessments of an individual's metabolic processes that could provide insight into biological pathway...
Comparative urinary metabolomics reveals unique and shared pathways in COVID-19 and liver diseases [0.03%]
比较尿液代谢组学揭示COVID-19和肝病中独特的途径及共享途径
Garima Juyal,Fariya Khan,Sidra Siddiqui et al.
Garima Juyal et al.
Introduction: The COVID-19 pandemic and liver diseases both cause significant metabolic disturbances, yet the specific mechanisms driving these changes remain poorly understood. ...
Plasma metabolomic signatures of all and cause-specific cancers: a multi-platform population-based study [0.03%]
基于多平台的流行病学研究获得全部及特定类型癌症的血浆代谢标志物
Yu Shuai,Rikje Ruiter,Bruno H Stricker et al.
Yu Shuai et al.
Introduction: Early diagnosis of cancer is essential for improving patient outcomes. Metabolomics analysis has shown promise in detecting cancer and distinguishing its metastatic burdens in previous studies. ...
Metabolite names and identifiers: how far are we from interoperability? [0.03%]
代谢物名称和标识符：我们距离互操作性还有多远？
Ghina Hajjar,Franck Giacomoni,Mathieu Umec et al.
Ghina Hajjar et al.
Introduction: Today, metabolomics literature suffers from ambiguity in metabolites’ nomenclature, making difficult intercomparison between publications and can lead to misinterpretations. Progress in the implementation o...
Metabolomic characteristics and mechanisms of subgingival plaque in MASLD patients with periodontitis [0.03%]
伴有牙周炎的MASLD患者龈下菌斑代谢组特征及机制研究
Jingli Zhu,Hai He,Yingli Li et al.
Jingli Zhu et al.
Introduction: Metabolic dysfunction-associated steatotic liver disease (MASLD) exhibits a significant comorbidity with periodontitis (PD), yet its molecular mechanisms remain unclear. This study aims to elucidate the meta...
NMR metabolomic profiling of cerebrospinal fluid from dogs with meningoencephalitis of unknown origin demonstrates metabolic similarities to multiple sclerosis [0.03%]
不明原因的脑膜脑炎犬脑脊液的核磁共振代谢组谱型与多发性硬化症类似
Rita Gonçalves,Gemma Walmsley,Thomas W Maddox et al.
Rita Gonçalves et al.
Introduction: Meningoencephalitis of unknown origin (MUO) in dogs is a debilitating and often fatal disease that shows similarities to multiple sclerosis (MS) in humans. The metabolomic profile of MUO has not been previou...
Plasma metabolomic signatures in patients with multidrug-resistant bacterial sepsis [0.03%]
耐多药细菌脓毒症患者的血浆代谢组学标志物
Jing Wang,Gang Luo,Peng Lv et al.
Jing Wang et al.
Background and objective: Multidrug-resistant (MDR) bacterial infections are a leading cause of sepsis-related death. A rapid method to identify patients with MDR infections upon hospital admission is urgently needed. Thi...
RPLC- and HILIC-based non-targeted metabolomics workflow for blood microsamples [0.03%]
基于RPLC和HILIC的血小微样品非目标代谢组学流程
Pauline Couacault,Michael Witting
Pauline Couacault
Introduction: Blood microsampling (BμS) has emerged as an alternative to invasive sampling methods, including blood and plasma sampling. Several studies have shown that BμS are suitable alternatives for analyzing endoge...
What's in a name? Metabolite identification: challenges and pitfalls in untargeted metabolomics [0.03%]
名实相副：非靶向代谢组学中代谢物鉴定的挑战与陷阱
Georgios Theodoridis,Oliver Fiehn,Michal Holčapek et al.
Georgios Theodoridis et al.
Background: The aim of metabolic phenotyping (metabotyping) is to discover and identify metabolites (including lipids) that can be used to characterize biological samples and differentiate between different physiological ...
Metabolomic signatures of high-intensity and sprint interval exercise/training in humans: a systematic review [0.03%]
高强度和冲刺间歇运动/训练的人类代谢标志物的系统回顾
Daniel Marques de Sá E Silva,Glykeria Avgerinou,Anatoli Petridou et al.
Daniel Marques de Sá E Silva et al.
Background: Exercise metabolomics investigates how physical activity alters the metabolome, with responses depending on exercise type, intensity, and duration. Intermittent high-intensity to supramaximal exercise produces...