Child Mental Health Research in Low- and Middle-Income Countries: A Twin-Family Feasibility Study in Nigeria [0.03%]
尼日利亚双生子家庭可行性研究：低收入和中等收入国家儿童心理健康研究
Olakunle Ayokunmi Oginni,Olatokunbo Oguns,Olusola Jeje et al.
Olakunle Ayokunmi Oginni et al.
Globally, most children and adolescents live in low- and middle-income (LAMI) countries. Despite the high and under-recognized mental health burden in these settings, there is little systematic research to inform cost-effective mental healt...
Genetic Overlap Between DSM-IV Major Depressive Disorder and Suicidal Behaviors: Evidence from Polygenic Risk Scores in Young Adult Twins [0.03%]
抑郁症与自杀行为的遗传重叠：年轻孪生双胞胎多基因风险评分证据
Nathan A Gillespie,Mei-Hsin Su,Séverine Lannoy et al.
Nathan A Gillespie et al.
Suicidal thoughts and behaviors (STBs) represent a significant public health concern. This study aimed to examine the extent to which polygenic risk scores (PRSs) for suicide attempt and major depression (MD) explain variance in suicidal id...
Dyslexia Polygenic Index and Socio-Economic Status Interaction Effects on Reading Skills in Australia and the United Kingdom [0.03%]
澳大利亚和英国多基因指数和社交经济地位对阅读技能的交互作用效应
Diana Bicona,Hayley S Mountford,Elinor C Bridges et al.
Diana Bicona et al.
Literacy is a significant predictor of important life outcomes, such as attained education and income (Ritchie and Bates in Psychol Sci 24(7):1301-1308, 2013. 10.1177/0956797612466268) yet difficulties in reading and spelling are common. Bo...
Proteome-Wide Mendelian Randomisation Study of Adverse Perinatal Outcomes [0.03%]
全蛋白质组范围的孟德尔随机化研究不良围产期结局的影响
Emily R Daubney,Christopher Flatley,Liang-Dar Hwang et al.
Emily R Daubney et al.
Despite significant advances in pre- and postnatal care over the last century, adverse pregnancy related events still occur frequently. We used Mendelian randomisation (MR) to investigate potential causal effects of the mother's and fetal b...
Genetic and Environmental Influences on Sweet Taste Liking and Related Traits: New Insights from Twin Cohorts [0.03%]
甜味喜好及其相关性状的遗传和环境影响：来自双胞胎队列的新观点
Rhiannon M Armitage,Vasiliki Iatridi,Darya Gaysina et al.
Rhiannon M Armitage et al.
Reducing sugar intake is a key component of global health policies and dietary guidelines. However, individuals vary substantially in sweet-liking, commonly characterized by sweet-liking status (extreme sweet-likers, moderate sweet-likers, ...
Genetic and Environmental Contributions To Gender Diversity: A Systematic Review of the Twin Literature [0.03%]
性别多样性遗传和环境因素的影响：双胞胎文献的系统性回顾
Will Conabere,Louise Bourchier,Sue Malta et al.
Will Conabere et al.
Amidst growing visibility of gender diversity, the aetiology of gender identity has become a subject of increasing public interest. Prompted by the growing public debate, we review here the extant twin literature regarding the origins of ge...
Education as a Modifier of Genetic Influence on Cognitive Ability in Older Adults [0.03%]
教育对老年人认知能力的基因影响的作用机制研究
Yu-Cheng Hsu,Mei-Chen Lin,Mei-Hsin Su et al.
Yu-Cheng Hsu et al.
Whether education modifies genetic influences on cognition has not been fully explored, especially in non-European populations. Using the older adult cohort from the Taiwan Biobank of East Asian populations, this study aimed to investigate ...
Familial Aggregation Patterns, Spousal Resemblance, and Family-Based Heritability of Adiposity-Related Traits: Insights from Tehran Cardiometabolic and Genetic Study (TCGS) [0.03%]
基于家族的遗传性、配偶相似性和与肥胖相关的代谢性状的家族聚集模式：德黑兰心脏代谢和基因组学研究(TCGS)的新见解
Parisa Riahi,Farshad Teymoori,Hossein Farhadnejad et al.
Parisa Riahi et al.
Asian residents frequently have a higher percentage of body fat in comparison to individuals with European ancestry, which increases their susceptibility to metabolic diseases. This study aimed to explore the familial resemblance patterns o...
Measuring the Associations Between Brain Morphometry and Polygenic Risk Scores for Substance use Disorders in Drug-Naive Adolescents [0.03%]
测量物质使用障碍的基因风险评分与青少年脑形态学之间的关联
Sydney Kramer,Mei-Hsin Su,Mallory Stephenson et al.
Sydney Kramer et al.
Substance use has been associated with differences in adult brain morphology; however, it is unclear whether these differences precede or are a result of substance use substance use. We investigated the impact of polygenic risk scores (PRSs...
Detecting mtDNA Effects with an Extended Pedigree Model: An Analysis of Statistical Power and Estimation Bias [0.03%]
利用扩展家系模型检测mtDNA效应：统计功效和估计偏差分析
Xuanyu Lyu,Michael D Hunter,S Alexandra Burt et al.
Xuanyu Lyu et al.
Mitochondrial DNA (mtDNA) plays a crucial role in numerous cellular processes, yet its impact on human complex behavior remains underexplored. The current paper proposes a novel covariance structure model with seven parameters to specifical...