EpiMix Based Novel Vaccine Candidate for Shigella: Evidence of Prophylactic Immunity in Balb/c Mice [0.03%]
基于EpiMix的新型志贺菌疫苗候选者：Balb/c小鼠预防免疫的有效性证据
Harish Padh,Bhrugu Yagnik,Drashya Sharma et al.
Harish Padh et al.
Multidrug resistant Shigella is one of the leading causes of mortality in children and infants. Availability of vaccine could prevent the Shigella infection and reduce the mortality. Conventional approaches of vaccine development against sh...
A Novel Multi-Epitopic Peptide Vaccine Candidate Against Helicobacter pylori: In-Silico Identification, Design, Cloning and Validation Through Molecular Dynamics [0.03%]
一种新型Helicobacter pylori多表位肽疫苗候选者：基于分子动力学的计算机识别、设计、克隆及验证研究
Pratik Ghosh,Swarnav Bhakta,Manojit Bhattacharya et al.
Pratik Ghosh et al.
Helicobacter pylori is a highly potential pathogen to colonize in the human stomach. This bacterial strain is now alarming serious health concern all over the world. Combating through available drugs is a difficult task due to lack of appro...
Could Dermaseptin Analogue be a Competitive Inhibitor for ACE2 Towards Binding with Viral Spike Protein Causing COVID19?: Computational Investigation [0.03%]
计算研究：皮肤病肽类似物可能是竞争性抑制剂ACE2与导致COVID19的病毒刺突蛋白结合？
P Chandra Sekar,R Rajasekaran
P Chandra Sekar
Initial phase of COVID-19 infection is associated with the binding of viral spike protein S1 receptor binding domain (RBD) with the host cell surface receptor, ACE2. Peptide inhibitors typically interact with spike proteins in order to bloc...
A Novel Design of Multi-epitope Vaccine Against Helicobacter pylori by Immunoinformatics Approach [0.03%]
一种基于免疫信息学方法的幽门螺杆菌多抗原表位疫苗的新设计
Junfei Ma,Jingxuan Qiu,Shuying Wang et al.
Junfei Ma et al.
Helicobacter pylori (H. pylori) is a gram-negative spiral bacterium that caused infections in half of the world's population and had been identified as type I carcinogen by the World Health Organization. Compared with antibiotic treatment w...
Immunoinformatics Driven Prediction of Multiepitopic Vaccine Against Klebsiella pneumoniae and Mycobacterium tuberculosis Coinfection and Its Validation via In Silico Expression [0.03%]
计算驱动的抗肺炎克雷伯氏菌和抗结核分枝杆菌复合疫苗的多表位疫苗的设计、表达及验证
Sidra Rahmat Ullah,Mahnoor Majid,Muhammad Ibrahim Rashid et al.
Sidra Rahmat Ullah et al.
Klebsiella pneumoniae and Mycobacterium tuberculosis coinfection is one of the most lethal combinations that has been becoming frequent yet, not diagnosed and reported properly. Due to the simultaneous occurrence of both infections, diagnos...
B Cell Epitopes of Four Fimbriae Antigens of Klebsiella pneumoniae: A Comprehensive In Silico Study for Vaccine Development [0.03%]
肺炎克雷伯菌四个菌毛抗原的B细胞表位：疫苗开发的全面生物信息学研究
Fatemeh Nemati Zargaran,Alisha Akya,Shahab Rezaeian et al.
Fatemeh Nemati Zargaran et al.
Klebsiella pneumoniae is one of the major causes of nosocomial infections worldwide which can cause several diseases in children and adults. The globally dissemination of hyper-virulent strains of K. pneumoniae and the emergence of antibiot...
Designing of Nucleocapsid Protein Based Novel Multi-epitope Vaccine Against SARS-COV-2 Using Immunoinformatics Approach [0.03%]
基于免疫信息学方法设计针对SARS-COV-2的新型多表位核酸蛋白疫苗
Janish Kumar,Rahila Qureshi,Someswar R Sagurthi et al.
Janish Kumar et al.
The COVID-19 disease is caused by SARS-CoV-2 and spreading rapidly worldwide with extremely high infection rate. Since effective and specific vaccine is not available to combat the deadly COVID-19, the objective of our study was to design a...
Proteomic Exploration of Listeria monocytogenes for the Purpose of Vaccine Designing Using a Reverse Vaccinology Approach [0.03%]
反向 vaccinology 方法用于李斯特菌单核增生性外膜蛋白探索的疫苗设计研究
Shivani Srivastava,Suraj Kumar Sharma,Vivek Srivastava et al.
Shivani Srivastava et al.
Listeriosis is a major foodborne infection provoked by a bacterium known as Listeria monocytogenes. It is one of the predominant causes of death in pregnant women, infants, and immunocompromised persons. Despite such fatal effects, until no...
Screening of FDA Approved Drugs Against SARS-CoV-2 Main Protease: Coronavirus Disease [0.03%]
针对SARS-CoV-2主要蛋白酶筛选FDA批准的药物：冠状病毒疾病
Vijayakumar Balakrishnan,Karthik Lakshminarayanan
Vijayakumar Balakrishnan
At the end of December 2019, a new strain of coronavirus was identified in the Wuhan city of Hubei province in China. Within a shorter period of time, an unprecedented outbreak of this strain was witnessed over the entire Wuhan city. This n...
Analysis of Putative Epitope Candidates of Mycobacterium tuberculosis Against Pakistani Human Leukocyte Antigen Background: An Immunoinformatic Study for the Development of Future Vaccine [0.03%]
结核分枝杆菌的潜在抗原表位候选物针对巴基斯坦人群的人白细胞抗原背景分析：对未来疫苗开发的免疫信息学研究
Malik Siddique Mahmood,Duaa Bin-T-Abid,Saba Irshad et al.
Malik Siddique Mahmood et al.
Tuberculosis (TB), a chronic disease caused by Mycobacterium tuberculosis (Mtb), is a global health issue across the world. Pakistan ranks fifth among the countries, which are facing, a significantly great number of mortalities and morbidit...