Computational Design of a Multi-epitope Vaccine Against Clostridium chauvoei: An Immunoinformatics Approach [0.03%]
计算设计克氏梭菌多抗原表位疫苗的免疫信息学方法
Çiğdem Yılmaz Çolak
Çiğdem Yılmaz Çolak
Blackleg is an infectious disease of animals that is commonly caused by Clostridium chauvoei and characterized by localized muscle necrosis. In this study, proteome-mining and immunoinformatics approaches were applied to identify novel anti...
Design of a Multi-epitope Vaccine Against Acinetobacter baumannii Using Immunoinformatics Approach [0.03%]
利用免疫信息学方法设计抗鲍曼不动杆菌多表位疫苗
Maryam Touhidinia,Fatemeh Sefid,Mozhgan Bidakhavidi
Maryam Touhidinia
Acinetobacter baumannii is one of the most successful pathogens causing nosocomial infections and has significantly multidrug-resistant. So far, there are no certain treatments to protect against infection with A. baumannii, therefore an ef...
Quest for Novel Preventive and Therapeutic Options Against Multidrug-Resistant Pseudomonas aeruginosa [0.03%]
寻找针对多重耐药绿脓杆菌的新预防和治疗方案的努力
Sidra Irum,Saadia Andleeb,Amjad Ali et al.
Sidra Irum et al.
Pseudomonas aeruginosa (P. aeruginosa) is a critical healthcare challenge due to its ability to cause persistent infections and the acquisition of antibiotic resistance mechanisms. Lack of preventive vaccines and rampant drug resistance phe...
In Silico Analysis of Potential Outer Membrane Beta-Barrel Proteins in Aeromonas hydrophila Pangenome [0.03%]
气单胞菌种系基因组中潜在的外膜蛋白质的计算机分析方法研究
Furqan Awan,Muhammad Muddassir Ali,Yuhao Dong et al.
Furqan Awan et al.
Outer membrane proteins (OMPs) of Aeromonas hydrophila have a variety of functional roles in virulence and pathogenesis and represent promising targets for vaccine development. The main objective of this study was to develop an in-silico mo...
Lessons Learned from Cutting-Edge Immunoinformatics on Next-Generation COVID-19 Vaccine Research [0.03%]
从免疫信息学前沿研究中获得的经验教训：下一代COVID-19疫苗研发的启示
Chiranjib Chakraborty,Ashish Ranjan Sharma,Manojit Bhattacharya et al.
Chiranjib Chakraborty et al.
Presently, immunoinformatics and bioinformatics approaches are contributing actively to COVID-19 vaccine research. The first immunoinformatics-based vaccine construct against SARS-CoV-2 was published in February 2020. Following this, immuno...
New Computational Approach for Peptide Vaccine Design Against SARS-COV-2 [0.03%]
针对SARS-CoV-2肽疫苗设计的新计算方法
Subhamoy Biswas,Smarajit Manna,Ashesh Nandy et al.
Subhamoy Biswas et al.
The design for vaccines using in silico analysis of genomic data of different viruses has taken many different paths, but lack of any precise computational approach has constrained them to alignment methods and some alignment-free technique...
Detecting the Dominant T and B Epitopes of Klebsiella pneumoniae Ferric Enterobactin Protein (FepA) and Introducing a Single Epitopic Peptide as Vaccine Candidate [0.03%]
肺炎克雷伯菌铁载体肠杆菌素蛋白（FepA）的主导T/B表位鉴定及单个表位肽疫苗候选物的筛选
Fatemeh Nemati Zargaran,Alisha Akya,Keyghobad Ghadiri et al.
Fatemeh Nemati Zargaran et al.
Klebsiella pneumoniae causes various human infections. Ferric enterobactin protein (FepA) is a conserved protein of K. pneumoniae with high immunogenicity. In the present study, using comprehensive in silico approaches the T and B cell-spec...
Protein Composition and Biomedical Potential of the Skin Secretion of Hylarana erythraea (Schlegel, 1837) (Anura: Ranidae) from Langkawi Archipelago, Kedah, Peninsular Malaysia [0.03%]
马来西亚半岛兰卡威群岛的红赤蛙（Hylarana erythraea）皮肤分泌物的蛋白质组成和生物医学潜力
Dasi Ong,Mohd Nazri Ismail,Shahriza Shahrudin
Dasi Ong
The skin secretion of amphibians is known for its high content of bioactive compounds. These bioactive compounds are essential for the advancement of biomedical industries. Four wild green paddy frogs, Hylarana erythraea, were collected fro...
Anticipation of Antigenic Sites for the Goal of Vaccine Designing Against Nipah Virus: An Immunoinformatics Inquisitive Quest [0.03%]
针对亨德拉病毒疫苗设计的抗原表位预测：免疫信息学研究
Suraj Kumar Sharma,Shivani Srivastava,Ajay Kumar et al.
Suraj Kumar Sharma et al.
With time, the Nipah virus has been proved as a fatal and dangerous pathogen for humanity. Nipah virus has its origin from bats and severely affects the respiratory as well as neurological organs. Regular outbreaks and unavailability of pro...
Designing of a Novel Fusion Protein Vaccine Candidate Against Human Visceral Leishmaniasis (VL) Using Immunoinformatics and Structural Approaches [0.03%]
基于免疫信息学和结构方法的人粘液病原性利什曼病融合蛋白疫苗设计研究
Amir Atapour,Farideh Ghalamfarsa,Samaneh Naderi et al.
Amir Atapour et al.
Leishmaniasis is caused by an obligate intracellular protozoan parasite. The clinical forms of leishmaniasis differ from cutaneous leishmaniasis, mucocutaneous leishmaniasis and visceral leishmaniasis (VL) which depend on the parasite speci...