Role of Antimicrobial Peptides in Treatment and Prevention of Mycobacterium Tuberculosis: A Review [0.03%]
宿主抗菌肽在防治结核杆菌感染中的作用及机制研究进展
Kanchan Mehta,Prince Sharma,Shama Mujawar et al.
Kanchan Mehta et al.
Tuberculosis (TB) is one of the leading cause of death worldwide, and the world is fighting with this global health emergency from the past 25 year. The current clinical interventions for the management of TB face a number of inherent chall...
The Effects of Metal Ions on the Cytotoxicity and Selectivity of a Histidine-Containing Lytic Peptide [0.03%]
组氨酸裂解肽的金属离子效应及其细胞毒性和选择性的影响
Long Chen,Sijia Dong,Jun F Liang
Long Chen
The histidine-containing peptide L5C (PAWRHAFHWAWHMLHKAA) is a histidine-rich lytic peptide. Interactions of some divalent metal ions with peptide L5C and their effects on the cell lysis activity of the peptide were studied. The presence of...
Development of Multi-epitope Based Subunit Vaccine Against Crimean-Congo Hemorrhagic Fever Virus Using Reverse Vaccinology Approach [0.03%]
利用反向 vaccinology 方法开发针对克里米亚刚果出血热病毒的多抗原亚单位疫苗
Md Ashik Imran,Md Rubiath Islam,Akash Saha et al.
Md Ashik Imran et al.
Crimean-Congo hemorrhagic fever (CCHF) is a viral disease caused by the Crimean-Congo hemorrhagic fever virus (CCHFV) of the Nairovirus genus. CCHF has occurred endemically in several regions of Africa, Southern Europe, and Central and Sout...
An Immunoinformatics Prediction of Novel Multi-Epitope Vaccines Candidate Against Surface Antigens of Nipah Virus [0.03%]
针对尼帕病毒表面抗原的新一代多表位疫苗候选物的免疫信息学预测
Md Mahfuzur Rahman,Joynob Akter Puspo,Ahmed Ahsan Adib et al.
Md Mahfuzur Rahman et al.
Nipah virus (NiV) is an emerging zoonotic virus causing outbreaks of encephalitis and respiratory illnesses in humans, with high mortality. NiV is considered endemic in Bangladesh and Southeast Asia. There are no licensed vaccines against N...
B-Cell Epitope Mapping from Eight Antigens of Candida albicans to Design a Novel Diagnostic Kit: An Immunoinformatics Approach [0.03%]
基于八种白色念珠菌抗原的B细胞表位 mapping以设计新型诊断试剂盒：免疫信息学方法
Farzaneh Vahedi,Younes Ghasemi,Amir Atapour et al.
Farzaneh Vahedi et al.
Invasive candidiasis is an emerging fungal infection and a leading cause of morbidity in health care facilities. Despite advances in antifungal therapy, increased antifungal drug resistance in Candida albicans has enhanced patient fatality....
An Immunoinformatic Strategy to Develop New Mycobacterium tuberculosis Multi-epitope Vaccine [0.03%]
一种开发新的多表位结核杆菌疫苗的免疫信息学策略
Morteza Ghandadi
Morteza Ghandadi
Mycobacterium tuberculosis causes a life-threatening disease known as tuberculosis (TB). In 2021, tuberculosis was the second cause of death after COVID-19 among infectious diseases. Latent life cycle and development of multidrug resistance...
Diagnostic Potential of the Serological Response to Synthetic Peptides from Mycobacterium tuberculosis Antigens for Discrimination Between Active and Latent Tuberculosis Infections [0.03%]
结核病发病的血清学诊断标志物研究
Zaida Araujo,Jacobus H de Waard,Milena Camargo et al.
Zaida Araujo et al.
Diagnosis and treatment of active tuberculosis (ATB) as well as latent tuberculosis infection (LTBI) are required for effective tuberculosis (TB) control, especially in TB endemic area. The usefulness of conventional tests to distinguish be...
Design of an Epitope-Based Peptide Vaccine Against Dengue Virus Isolate from Eastern Uttar Pradesh, India [0.03%]
一种针对印度东部 Utter Pradish 州登革病毒表位肽疫苗的设计
Siddharth Gupta,Ajay Kumar
Siddharth Gupta
Dengue outbreaks are a serious public health concern that occurs on a regular basis in various locations of India. According to the Government of India's National Center for Vector-Borne Disease Control, a total of 1,23,106 dengue cases wer...
Pritam V Bagwe,Priyal V Bagwe,Sai Srinivas Ponugoti et al.
Pritam V Bagwe et al.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been prevalent in the humans since 2019 and has given rise to a pandemic situation. With the discovery and ongoing use of drugs and vaccines against SARS-CoV-2, there is still...