Prediction of Conformational and Linear B-Cell Epitopes on Envelop Protein of Zika Virus Using Immunoinformatics Approach [0.03%]
使用免疫信息学方法预测寨卡病毒包膜蛋白的构象和线性B细胞表位
Kirti Srivastava,Vivek Srivastava
Kirti Srivastava
The current spread of Zika virus infection in India has become a public health issue due to the virus's possible link to birth abnormalities and neurological disorders. There is a need for enhanced vaccines or drugs as a result of its epide...
Multi Epitopic Peptide Based Vaccine Development Targeting Immobilization Antigen of Ichthyophthirius multifiliis: A Computational Approach [0.03%]
针对多线虫 immobilization 抗原的多表位肽基疫苗研发：一种计算方法
Pratik Ghosh,Prasanta Patra,Niladri Mondal et al.
Pratik Ghosh et al.
The white spot disease causes significant damage to global aquaculture production. A prominent vaccine, eliciting the immunogenicity of freshwater fishes against Ichthyophthirius multifiliis yet to be developed. Thus, an Immunoinformatic dr...
Le Yi Chia,Palanirajan Vijayaraj Kumar,Marwan Abdelmahmoud Abdelkarim Maki et al.
Le Yi Chia et al.
In the design and development of therapeutic agents, macromolecules with restricted structures have stronger competitive edges than linear biological entities since cyclization can overcome the limitations of linear structures. The common i...
Recent Patents and FDA-Approved Drugs Based on Antiviral Peptides and Other Peptide-Related Antivirals [0.03%]
基于抗病毒肽和其他肽类抗病毒药物的近期专利和FDA批准的药物
Masoumeh Sadat Mousavi Maleki,Soroush Sardari,Ali Ghandehari Alavijeh et al.
Masoumeh Sadat Mousavi Maleki et al.
In spite of existing cases of severe viral infections with a high mortality rate, there are not enough antiviral drugs and vaccines available for the prevention and treatment of such diseases. In addition, the increasing reports of the emer...
Immunoinformatics Analysis of Citrullinated Antigen as Potential Multi-peptide Lung Cancer Vaccine Candidates for Indonesian Population [0.03%]
瓜氨酸化抗原作为潜在的多肽肺癌疫苗候选者的免疫信息学分析面向印尼人群
Angelika Hermawan,Fedric Intan Damai,Leon Martin et al.
Angelika Hermawan et al.
Non-small-cell lung cancer (NSCLC) is the most common lung cancer which has the highest mortality rate in Indonesia. One of the trends in treating cancer is by utilizing peptide vaccines, an immunotherapeutic approach that aims to stimulate...
Prediction of Potential Drug Targets and Vaccine Candidates Against Antibiotic-Resistant Pseudomonas aeruginosa [0.03%]
对抗抗生素耐药的铜绿假单胞菌的潜在药物靶点和疫苗候选物的预测
Fatemeh Sadat Shamsinejad,Zahra Zafari
Fatemeh Sadat Shamsinejad
Pseudomonas aeruginosa is one of the leading causes of nosocomial infections, characterized by increasing antibiotic resistance, severity and mortality. Therefore, numerous efforts have been made nowadays to identify new therapeutic targets...
Peptide ILE-GLU-TRP (Stemokin) Potential Adjuvant Stimulating a Balanced Immune Response [0.03%]
肽ILE-GLU-TRP（茎激素）作为潜在免疫佐剂刺激平衡免疫反应的能力
Vladislav Deigin,Dmitry Koroev,Olga Volpina
Vladislav Deigin
Vaccines are widely used worldwide to prevent and protect from various infections. A variety of modern approaches to developing prophylactic and therapeutic vaccines is growing. In almost all cases, adjuvants are necessary to obtain an effe...
SARS-CoV-2 Delta Variant is Recognized Through GRP78 Host-Cell Surface Receptor, In Silico Perspective [0.03%]
从计算角度揭示新型冠状病毒德尔塔变异株通过GRP78宿主细胞表面受体识别机制
Abdo A Elfiky,Ibrahim M Ibrahim,Alaa M Elgohary
Abdo A Elfiky
Different SARS-CoV-2 new variants emerged and spread during the past few months, sparking infections and death counts. The new variant B.1.617 (delta variant) sparked in India in the past few months, causing the highest records. The B.1.617...
The Updated Review on Plant Peptides and Their Applications in Human Health [0.03%]
植物肽及在人类健康中应用的研究进展综述
Saiprahalad Mani,Smruti B Bhatt,Vinduja Vasudevan et al.
Saiprahalad Mani et al.
Biologically active plant peptides, consisting of secondary metabolites, are compounds (amino acids) utilized by plants in their defense arsenal. Enzymatic processes and metabolic pathways secrete these plant peptides. They are also known f...
Exploratory Algorithm of a Multi-epitope-based Subunit Vaccine Candidate Against Cryptosporidium hominis: Reverse Vaccinology-Based Immunoinformatic Approach [0.03%]
基于反向 vaccinology 的免疫信息学方法探索新隐孢子虫（C.hominis）多表位亚单位疫苗候选物的算法
Mahamudul Hasan,Mukthar Mia
Mahamudul Hasan
Cryptosporidiosis is the leading protozoan-induced cause of diarrheal illness in children, and it has been linked to childhood mortality, malnutrition, cognitive development, with retardation of growth. Cryptosporidium hominis, the anthropo...