Correction: Extreme Physiology Extreme Tolerance to Hypoxia, Hypercapnia, and Pain in the Naked Mole-Rat [0.03%]
关于无毛 mole-rat 耐低氧、耐高二氧化碳和痛阈极端生理适应性的更正文章
Thomas J Park,Jane Reznick
Thomas J Park
The cryo-EM 3D image reconstruction of isolated Lethocerus indicus Z-discs [0.03%]
孤立的印度鳃足虫Z线的冷冻电子显微镜三维图像重建
Fatemeh Abbasi Yeganeh,Corinne Summerill,Zhongjun Hu et al.
Fatemeh Abbasi Yeganeh et al.
The Z-disk of striated muscle defines the ends of the sarcomere, which repeats many times within the muscle fiber. Here we report application of cryoelectron tomography and subtomogram averaging to Z-disks isolated from the flight muscles o...
Zebrafish as a model for cardiac disease; Cryo-EM structure of native cardiac thin filaments from Danio Rerio [0.03%]
斑马鱼心脏疾病模型；斑马鱼原初心肌细丝的冷冻电镜结构分析
Marston Bradshaw,John M Squire,Edward Morris et al.
Marston Bradshaw et al.
Actin, tropomyosin and troponin, the proteins that comprise the contractile apparatus of the cardiac thin filament, are highly conserved across species. We have used cryo-EM to study the three-dimensional structure of the zebrafish cardiac ...
Jennifer R Fleming,Iljas Müller,Thomas Zacharchenko et al.
Jennifer R Fleming et al.
The thick filament-associated A-band region of titin is a highly repetitive component of the titin chain with important scaffolding properties that support thick filament assembly. It also has a demonstrated link to human disease. Despite i...
Characteristics of the right atrial and right ventricular contractility in a model of monocrotaline-induced pulmonary arterial hypertension [0.03%]
建立鬼笔环肽致肺动脉高压模型右心室及右心房收缩特性的研究
Oksana P Gerzen,Ruslan V Lisin,Alexander A Balakin et al.
Oksana P Gerzen et al.
Pulmonary arterial hypertension (PAH) leads to changes in the pump function of the heart and causes right-sided myocardial hypertrophy and heart failure. This study was the first to compare the contractile characteristics of the multicellul...
Bioinformatics analysis of paravertebral muscles atrophy in adult degenerative scoliosis [0.03%]
成人退变性侧弯椎旁肌肉萎缩的生物信息学分析
Zhigang Rong,Zhong Yang,Chengmin Zhang et al.
Zhigang Rong et al.
Paravertebral muscles (PVM) act as one of the major dynamic factors to maintain human upright activities and play a remarkable role in maintaining the balance of the trunk. Adult degenerative scoliosis (ADS) has become one of the important ...
The vertebrate muscle superlattice: discovery, consequences, and link to geometric frustration [0.03%]
脊椎动物肌肉超晶格：发现、影响及与几何学阻挫的关系
Rick P Millane,Pradeep K Luther
Rick P Millane
Early x-ray diffraction studies of muscle revealed spacings larger than the basic thick filament lattice spacing and led to a number of speculations on the mutual rotations of the filaments in the myosin lattice. The nature of the arrangeme...
Lata Govada,Naomi E Chayen
Lata Govada
The techniques of X-ray protein crystallography, NMR and high-resolution cryo-electron microscopy have all been used to determine the high-resolution structure of proteins. The most-commonly used method, however, remains X-ray crystallograp...
Cryo-electron tomography of intact cardiac muscle reveals myosin binding protein-C linking myosin and actin filaments [0.03%]
cryo-电子断层扫描显示完整的-heart肌肉中的肌球蛋白结合蛋白-C将肌球蛋白和肌动蛋白丝连接在一起
Xinrui Huang,Iratxe Torre,Michele Chiappi et al.
Xinrui Huang et al.
Myosin binding protein C (MyBP-C) is an accessory protein of the thick filament in vertebrate cardiac muscle arranged over 9 stripes of intervals of 430 Å in each half of the A-band in the region called the C-zone. Mutations in cardiac MyB...
Kenneth A Taylor
Kenneth A Taylor
The structure of the thin, actin-containing filament of muscle is both highly conserved across a broad range of muscle types and is now well understood. The structure of the thick, myosin-containing filaments of striated muscle are quite va...