Stability of two beta-tropomyosin isoforms: effects of mutation Arg91Gly [0.03%]
两种β-原肌球蛋白同工型的稳定性：Arg91Gly突变的影响
Ilya Nevzorov,Charles Redwood,Dmitrii Levitsky
Ilya Nevzorov
In order to comprehend the domain structure of two beta-tropomyosin (beta-Tm) isoforms (skeletal muscle and smooth muscle beta-Tm) and the influence of the disease-causing mutation Arg91Gly on it, we studied the thermal unfolding of these t...
Mechanical properties of the extracellular matrix alter expression of smooth muscle protein LPP and its partner palladin; relationship to early atherosclerosis and vascular injury [0.03%]
细胞外基质的机械性能改变平滑肌蛋白LPP及其伙伴蛋白palladin的表达；与早期动脉粥样硬化和血管损伤的关系
Li Jin,Nicole E Hastings,Brett R Blackman et al.
Li Jin et al.
Lipoma preferred partner (LPP) localizes to focal adhesions/dense bodies, is selectively expressed in smooth muscle cells (SMC) and enhances cell migration. SMCs cultured on denatured collagen or on a rigid substrate, up regulated expressio...
Current techniques for the study of troponin I phosphorylation in human heart [0.03%]
人类心脏肌钙蛋白I磷酸化研究的当前技术
Clare E Gallon
Clare E Gallon
Cardiac troponin I phosphorylation has been shown to be reduced in human heart failure and hypertrophic cardiomyopathy using the increasingly popular Pro-Q Diamond phosphoprotein gel stain. In this brief report I discuss the use of Western ...
Single amino acid sequence polymorphisms in rat cardiac troponin revealed by top-down tandem mass spectrometry [0.03%]
基于串联质谱的单氨基酸多态性的大鼠心肌肌钙蛋白多肽序列测定
Raquel Sancho Solis,Ying Ge,Jeffery W Walker
Raquel Sancho Solis
Heterotrimeric cardiac troponin (cTn) is a critical component of the thin filament regulatory complex in cardiac muscle. Two of the three subunits, cTnI and cTnT, are subject to post-translational modifications such as proteolysis and phosp...
Marcus C Schaub
Marcus C Schaub
Dietary protein content influences both growth and size distribution of anterior and posterior muscle fibres in juveniles of Pagellus bogaraveo (Brunnich) [0.03%]
饮食蛋白含量影响Pagellus bogaraveo幼鱼前后肌纤维生长和大小分布
P Silva,L M P Valente,M H Galante et al.
P Silva et al.
Muscle cellularity was studied in Pagellus bogaraveo juveniles fed on diets with different protein contents. Measured in transversal body sections, at both post-opercular and post-anal locations, the morphometric variables estimated were: t...
Zacharias Orfanos
Zacharias Orfanos
One of the advantages of using Drosophila melanogaster as a model organism is our knowledge of its genetics combined with its genetic versatility. Over the years, a range of transgenic tools have been developed that allow easy genetic manip...
Nazha Hamdani,Monique de Waard,Andrew E Messer et al.
Nazha Hamdani et al.
In healthy human myocardium a tight balance exists between receptor-mediated kinases and phosphatases coordinating phosphorylation of regulatory proteins involved in cardiomyocyte contractility. During heart failure, when neurohumoral stimu...
Jaakko Sarparanta
Jaakko Sarparanta
Myospryn (CMYA5, cardiomyopathy-associated 5) is a muscle-specific member of the TRIM superfamily, discovered a few years ago. Properties and functions of the little-studied protein remain largely enigmatic, but identified interactions have...