Myostatin knockout mice increase oxidative muscle phenotype as an adaptive response to exercise [0.03%]
肌生长抑制素基因敲除小鼠的氧化型肌肉表型适应运动训练的调控机制研究
Antonios Matsakas,Etienne Mouisel,Helge Amthor et al.
Antonios Matsakas et al.
Myostatin-deficient mice (MSTN (-/-)) display excessive muscle mass and this is associated with a profound loss of oxidative metabolic properties. In this study we analysed the effect of two endurance-based exercise regimes, either a forced...
The role of tropomyosin isoforms and phosphorylation in force generation in thin-filament reconstituted bovine cardiac muscle fibres [0.03%]
牛心脏肌肉纤维中肌纤蛋白异构体和磷酸化在细丝重构中的作用力产生中的作用
Xiaoying Lu,David H Heeley,Lawrence B Smillie et al.
Xiaoying Lu et al.
The thin filament extraction and reconstitution protocol was used to investigate the functional roles of tropomyosin (Tm) isoforms and phosphorylation in bovine myocardium. The thin filament was extracted by gelsolin, reconstituted with G-a...
A reappraisal of the Ca2+ dependence of fast inactivation of Ca2+ release in frog skeletal muscle [0.03%]
对蛙骨骼肌Ca2+释放快速失活的钙离子依赖性的再评价
J Fernando Olivera,Gonzalo Pizarro
J Fernando Olivera
Two procedures to inhibit Ca(2+) release designed to differentiate between local and common pool mechanisms for the Ca(2+) dependent, fast inactivation of Ca(2+) release in skeletal muscle of the frog were compared. Inhibition by voltage de...
Obituary S.V. Perry [0.03%]
佩里教授逝世
John Gergely
John Gergely
Expression of HGF and IGF-1 during regeneration of masseter muscle in mdx mice [0.03%]
mdx小鼠咬肌再生过程中HGF和IGF-1的表达
Hidemitsu Honda,Shinichi Abe,Ryo Ishida et al.
Hidemitsu Honda et al.
This study investigated the expression of the growth factors HGF and IGF-1 during the process of muscle regeneration in mdx mice. HGF and IGF-1 are reportedly expressed during the regeneration of muscle tissue in vitro. However, few studies...
Analysing force-pCa curves [0.03%]
分析力-pCa曲线
John S Walker,Xiaotao Li,Peter M Buttrick
John S Walker
We investigated three forms of the Hill equation used to fit force-calcium data from skinned muscle experiments; Two hyperbolic forms that relate force to calcium concentration directly, and a sigmoid form that relates force to the -log(10)...
Marcus C Schaub
Marcus C Schaub
Species-specific differences in the Pro-Ala rich region of cardiac myosin binding protein-C [0.03%]
心脏肌联蛋白C结构域种属特异性差异的Pro-Ala丰富区段研究
Justin F Shaffer,Samantha P Harris
Justin F Shaffer
Cardiac myosin binding protein-C (cMyBP-C) is an accessory protein found in the A-bands of vertebrate sarcomeres and mutations in the cMyBP-C gene are a leading cause of familial hypertrophic cardiomyopathy. The regulatory functions of cMyB...
A piece of the human heart: variance of protein phosphorylation in left ventricular samples from end-stage primary cardiomyopathy patients [0.03%]
人左心室样本中蛋白磷酸化的个体化差异-来自终末期原发性心肌病患者的数据
Sabine J van Dijk,Rozemarije A Holewijn,Anouk Tebeest et al.
Sabine J van Dijk et al.
Cardiomyocyte contraction is regulated by phosphorylation of sarcomeric proteins. Throughout the heart regional and transmural differences may exist in protein phosphorylation. In addition, phosphorylation of sarcomeric proteins is altered ...
Cellular mechanisms and local progenitor activation to regulate skeletal muscle mass [0.03%]
调控肌肉质量的细胞机制和局部干细胞活化
Marco Cassano,Mattia Quattrocelli,Stefania Crippa et al.
Marco Cassano et al.
Skeletal muscle hypertrophy is a result of increased load, such as functional and stretch-overload. Activation of satellite cells and proliferation, differentiation and fusion are required for hypertrophy of overloaded skeletal muscles. On ...