ROCK inhibition prevents fetal serum-induced alteration in structure and function of organ-cultured mesenteric artery [0.03%]
ROCK抑制可防止胎牛血清所致肠系膜动脉结构和功能的改变
Yang Hoon Huh,Qian Zhou,James K Liao et al.
Yang Hoon Huh et al.
Chronic treatment with fetal bovine serum (FBS) causes contractility reduction, morphological alteration and DNA synthesis in organ-cultured vascular tissues. Here, we tested the hypothesis that chronic inhibition of ROCK has a protective e...
Tomohiro Kurisaki,Aki Masuda,Shiho Nakagiri et al.
Tomohiro Kurisaki et al.
We established a novel monoclonal antibody, Yaksa that is specific to a subpopulation of myogenic cells. The Yaksa antigen is not expressed on the surface of growing myoblasts but only on a subpopulation of myogenin-positive myocytes. When ...
Clara Franzini-Armstrong
Clara Franzini-Armstrong
Sherwin S Lehrer,Socheata Ly,Franklin Fuchs
Sherwin S Lehrer
Tropomyosin (Tm) purified from skeletal and cardiac muscle often contains disulfide bonds due to oxidation of cysteine groups that are in close proximity in the coiled-coil structure. Are these disulfide crosslinks present in the muscle or ...
The actin associated protein palladin in smooth muscle and in the development of diseases of the cardiovasculature and in cancer [0.03%]
肌动蛋白相关蛋白palladin在平滑肌及心血管疾病和癌症发展中的作用
Li Jin
Li Jin
Palladin is an actin associated protein serving as a cytoskeleton scaffold, and actin cross linker, localizing at stress fibers, focal adhesions, and other actin based structures. Recent studies showed that palladin plays a critical role in...
In vitro expression profiling of myostatin, follistatin, decorin and muscle-specific transcription factors in adult caprine contractile myotubes [0.03%]
成年山羊收缩性肌管中肌肉生长抑制素、卵泡抑素、角质素和肌肉特异性转录因子的体外表达谱分析
A K Tripathi,U V Ramani,D N Rank et al.
A K Tripathi et al.
Skeletal muscle is one of the several adult postmitotic tissues that retain the capacity to regenerate, which relies on a population of quiescent precursors, termed satellite cells. Proliferation and differentiation of myoblasts to form mat...
Biomechanics of the sarcolemma and costameres in single skeletal muscle fibers from normal and dystrophin-null mice [0.03%]
正常小鼠和缺失dystrophin基因小鼠单个骨骼肌纤维的sarcolemma和costamere的生物力学性能研究
K P García-Pelagio,R J Bloch,A Ortega et al.
K P García-Pelagio et al.
We studied the biomechanical properties of the sarcolemma and its links through costameres to the contractile apparatus in single mammalian myofibers of Extensor digitorum longus muscles isolated from wild (WT) and dystrophin-null (mdx) mic...
TGF-β isoforms inhibit IGF-1-induced migration and regulate terminal differentiation in a cell-specific manner [0.03%]
转化生长因子-β各亚型以细胞特异性方式抑制胰岛素样生长因子-1诱导的迁移并调节终末分化
Elske J Schabort,Mathilde van der Merwe,Carola U Niesler
Elske J Schabort
Following muscle injury, the damaged tissue and influx of inflammatory cells stimulate the secretion of growth factors and cytokines to initiate repair processes. This release of chemotactic signaling factors activates resident precursor ce...
The effect of skeletal myosin light chain kinase gene ablation on the fatigability of mouse fast muscle [0.03%]
骨骼肌球蛋白轻链激酶基因缺失对小鼠快肌纤维疲劳的影响研究
William Gittings,Jiang Huang,Ian C Smith et al.
William Gittings et al.
Contraction-induced activation of a skeletal muscle specific Ca(2+) and calmodulin dependent myosin light chain kinase (skMLCK) catalyzes phosphorylation of the myosin regulatory light chain (RLC), a reaction that potentiates twitch force. ...