Skeletal muscle satellite cell migration to injured tissue measured with 111In-oxine and high-resolution SPECT imaging [0.03%]
用111Ind-氧乙醇和高分辨率SPECT成像测定骨骼肌卫星细胞向受损组织迁移的情况
Jennifer L Elster,Christopher R Rathbone,Zhonglin Liu et al.
Jennifer L Elster et al.
The delivery of adult skeletal muscle stem cells, called satellite cells, to several injured muscles via the circulation would be useful, however, an improved understanding of cell fate and biodistribution following their delivery is import...
The mechanical activation of mTOR signaling: an emerging role for late endosome/lysosomal targeting [0.03%]
mTOR信号的机械激活:晚期内体/溶酶体靶向的作用机制不容小觑
Brittany L Jacobs,Craig A Goodman,Troy A Hornberger
Brittany L Jacobs
It is well recognized that mechanical signals play a critical role in the regulation of skeletal muscle mass, and the maintenance of muscle mass is essential for mobility, disease prevention and quality of life. Furthermore, over the last 1...
A re-interpretation of the rate of tension redevelopment (k(TR)) in active muscle [0.03%]
肌活组织中张力再发育速度(kTR)的释义研究
Li Wang,Masataka Kawai
Li Wang
A slackening to zero tension by large length release (~20%) and a restretch of active muscle fibres cause a fall and a redevelopment in tension. According to the model of Brenner (Proc Natl Acad Sci USA 85(9):3265-3269, 1988), the rate cons...
Myosin phosphorylation and force potentiation in skeletal muscle: evidence from animal models [0.03%]
骨骼肌肌球蛋白磷酸化与力增强:动物模型证据
Rene Vandenboom,William Gittings,Ian C Smith et al.
Rene Vandenboom et al.
The contractile performance of mammalian fast twitch skeletal muscle is history dependent. The effect of previous or ongoing contractile activity to potentiate force, i.e. increase isometric twitch force, is a fundamental property of fast s...
In vitro myoblast motility models: investigating migration dynamics for the study of skeletal muscle repair [0.03%]
体外肌细胞运动模型:用于探究骨骼肌修复中迁移动力学的研究
K P Goetsch,K H Myburgh,Carola U Niesler
K P Goetsch
Skeletal muscle repair requires the migration of myoblasts (activated satellite cells) both to the injury site and then within the wound to facilitate cellular alignment in preparation for differentiation, fusion and eventual healing. Along...
Quantifying SOCE fluorescence measurements in mammalian muscle fibres. The effects of ryanodine and osmotic shocks [0.03%]
肌浆网释放引起的SOCE的荧光定量。ryanodine和高渗休克的影响
Pura Bolaños,Alis Guillen,Adriana Gámez et al.
Pura Bolaños et al.
We have quantified Ca(2+) entry through store operated calcium channels in mice muscle fibres, measuring the rates of change of myoplasmic [Ca(2+)], d[Ca(2+)](myo)/dt, and of Ca(2+) removal, d[Ca(2+)](Removal)/dt, turning store operated cal...
Introducing a special edition of the Journal of Muscle Research and Cell Motility on tropomyosin: form and function [0.03%]
肌动蛋白结合蛋白:功能与结构——《肌肉研究与细胞运动性杂志》专题介绍
Steven Marston,Matthias Gautel
Steven Marston
Alterations of dystrophin-associated glycoproteins in the heart lacking dystrophin or dystrophin and utrophin [0.03%]
缺乏dystrophin或同时缺乏dystrophin和utrophin的心脏中与dystrophin相关的糖蛋白的改变
Katharine M Sharpe,Monica D Premsukh,DeWayne Townsend
Katharine M Sharpe
Heart disease is a leading cause of death in patients with Duchenne muscular dystrophy (DMD). Patients with DMD lack the protein dystrophin, which is widely expressed in striated muscle. In skeletal muscle, the loss of dystrophin results in...
Katalin Pinter,Robert T Grignani,Hugh Watkins et al.
Katalin Pinter et al.
The trimeric protein AMP-activated protein kinase (AMPK) is an important sensor of energetic status and cellular stress, and mutations in genes encoding two of the regulatory γ subunits cause inherited disorders of either cardiac or skelet...
Influence of chronic food deprivation on structure-function relationship of juvenile rat fast muscles [0.03%]
慢性食物限制对幼年大鼠快肌结构-功能关系的影响
Azucena Ruiz-Rosado,Héctor A Cabrera-Fuentes,Cecilia González-Calixto et al.
Azucena Ruiz-Rosado et al.
In the present study, we analyze the influence of chronic undernutrition on protein expression, muscle fiber type composition, and fatigue resistance of the fast extensor digitorum longus (EDL) muscle of male juvenile rats (45 ± 3 days of ...