Guangming Li,Xiangli Ye,Xiyang Peng et al.
Guangming Li et al.
CXXC5 is a member of the CXXC-type zinc-finger domain containing protein family, which is suggested to function in gene transcription, cell adhesion and cytoskeleton organization. Previous studies have revealed that CXXC5 is expressed in sk...
Forgotten research from 19th century: science should not follow fashion [0.03%]
十九世纪被遗忘的研究：科学研究不应随波逐流
Stefan Galler
Stefan Galler
The fine structure of cross-striated muscle and its changes during contraction were known already in considerable detail in the 19th century. This knowledge was the result of studying birefringence properties of muscle fibres under the pola...
The disorders of the calcium release unit of skeletal muscles: what have we learned from mouse models? [0.03%]
骨骼肌钙释放单位障碍的研究进展——从模式小鼠模型获得的新认识
Marta Canato,Paola Capitanio,Carlo Reggiani et al.
Marta Canato et al.
Calcium storage, release, and reuptake are essential for normal physiological function of muscle. Several human skeletal muscle disorders can arise from dysfunction in the control and coordination of these three critical processes. The rele...
Non-crossbridge forces in activated striated muscles: a titin dependent mechanism of regulation? [0.03%]
激活的条纹肌中的非跨桥力：一种由Titin介导的调节机制？
Dilson E Rassier,Felipe S Leite,Marta Nocella et al.
Dilson E Rassier et al.
When skeletal muscles are stretched during activation in the absence of myosin-actin interactions, the force increases significantly. The force remains elevated throughout the activation period. The mechanism behind this non-crossbridge for...
Myogenic progenitors and imaging single-cell flow analysis: a model to study commitment of adult muscle stem cells [0.03%]
肌源性前体和单细胞流动分析成像：研究成人肌肉干细胞分化承诺的模型
Martin Trapecar,Robi Kelc,Lidija Gradisnik et al.
Martin Trapecar et al.
Research on skeletal muscles suffers from a lack of appropriate human models to study muscle formation and regeneration on the regulatory level of single cells. This hampers both basic understanding and the development of new therapeutic ap...
Impact of tropomyosin isoform composition on fast skeletal muscle thin filament regulation and force development [0.03%]
骨骼肌原肌球蛋白异构体组成对快速骨骼肌细丝调节和力产生影响的研究
B Scellini,N Piroddi,G V Flint et al.
B Scellini et al.
Tropomyosin (Tm) plays a central role in the regulation of muscle contraction and is present in three main isoforms in skeletal and cardiac muscles. In the present work we studied the functional role of α- and βTm on force development by ...
G J M Stienen
G J M Stienen
Heart failure is a multi-factorial progressive disease in which eventually the contractile performance of the heart is insufficient to meet the demands of the body, even at rest. A distinction can be made on the basis of the cause of the di...
Emerging importance of oxidative stress in regulating striated muscle elasticity [0.03%]
氧化应激在调节肌动条状肌弹性中的重要作用不容忽视
Lisa Beckendorf,Wolfgang A Linke
Lisa Beckendorf
The contractile function of striated muscle cells is altered by oxidative/nitrosative stress, which can be observed under physiological conditions but also in diseases like heart failure or muscular dystrophy. Oxidative stress causes oxidat...
Michael A Geeves,Sarah E Hitchcock-DeGregori,Peter W Gunning
Michael A Geeves
Tropomyosin, a ubiquitous protein in animals and fungi, is associated with the actin cytoskeleton and is involved with stabilising actin filaments and regulating the interaction of the filament with other actin binding proteins. The protein...
Important announcement: a rational nomenclature for tropomyosin variants [0.03%]
重要公告：肌球蛋白变异体的命名法规范化问题
Steven Marston
Steven Marston
In an article in this edition of the Journal of Muscle Research and Cell Motility, Geeves, Hitchcock-DiGregori and Gunning present a nomenclature founded on the gene and exon structure of tropomyosin that is both clear and unambiguous. More...