Tábata L Nascimento,Meiricris T Silva,Elen H Miyabara
Tábata L Nascimento
This study investigated the effect of the heat shock protein inducer O-[3-piperidino-2-hydroxy-1-propyl]-nicotinic amidoxime (BGP-15) on the morphology and contractile function of regenerating soleus muscles from mice. Cryolesioned soleus m...
The expression of aquaporin-4 is regulated based on innervation in skeletal muscles [0.03%]
基底神经节对骨骼肌中水通道蛋白-4表达的调节作用
Minenori Ishido,Tomohiro Nakamura
Minenori Ishido
Aquaporin-4 (AQP4) is a selective water channel, which expresses on the plasma membrane of myofibers and regulates the osmotic pressure, energy metabolism and morphological changes in myofibers by modulating water transport across sarcolemm...
Development of apical hypertrophic cardiomyopathy with age in a transgenic mouse model carrying the cardiac actin E99K mutation [0.03%]
携带心脏肌动蛋白E99K突变转基因小鼠发育性心尖肥厚型心肌病的年龄依赖性变化
Li Wang,Fan Bai,Qing Zhang et al.
Li Wang et al.
In both humans and mice, the Glu-99-Lys (E99K) mutation in the cardiac actin gene (ACTC) results in little understood apical hypertrophic cardiomyopathy (AHCM). To determine how cross-bridge kinetics change with AHCM development, we applied...
D George Stephenson,David J Miller
D George Stephenson
Are mechanically sensitive regulators involved in the function and (patho)physiology of cerebral palsy-related contractures? [0.03%]
与脑瘫相关的肌萎缩的功能和(病理)生理有关的机械敏感调节因子中涉及了哪些?
Jessica Pingel,Frank Suhr
Jessica Pingel
Skeletal muscle tissue is mechanosensitive, as it is able to sense mechanical impacts and to translate these into biochemical signals making the tissue adapt. Among its mechanosensitive nature, skeletal muscle tissue is the largest metaboli...
Changes in contractile and metabolic parameters of skeletal muscle as rats age from 3 to 12 months [0.03%]
大鼠自3月龄至12月龄骨骼肌收缩及代谢参数的变化规律研究
Hongyang Xu,Graham D Lamb,Robyn M Murphy
Hongyang Xu
Laboratory rats are considered mature at 3 months despite that musculoskeletal growth is still occurring. Changes in muscle physiological and biochemical characteristics during development from 3 months, however, are not well understood. Wh...
Martina Krüger
Martina Krüger
Joseph M Chalovich,Theresia Kraft,Leepo C Yu
Joseph M Chalovich
When signalling goes wrong: pathogenic variants in structural and signalling proteins causing cardiomyopathies [0.03%]
信号异常所致的心肌病:结构性和信号传导蛋白的致病变异体
Mehroz Ehsan,He Jiang,Kate L Thomson et al.
Mehroz Ehsan et al.
Cardiomyopathies are a diverse group of cardiac disorders with distinct phenotypes, depending on the proteins and pathways affected. A substantial proportion of cardiomyopathies are inherited and those will be the focus of this review artic...