Nora Klöting,Matthias Blüher
Nora Klöting
Obesity is frequently associated with chronic inflammation, metabolic and vascular alterations which predispose to the development of the Metabolic Syndrome (MetS). However, the individual obesity-related risk for the MetS is not determined...
Jang H Youn
Jang H Youn
Overconsumption of dietary fat contributes to the development of obesity and metabolic syndrome. Recent evidence suggests that high dietary fat may promote these metabolic states not only by providing calories but also by inducing impaired ...
Soo Lim,Robert H Eckel
Soo Lim
Metabolic syndrome is a disorder based on insulin resistance. Metabolic syndrome is diagnosed by a co-occurrence of three out of five of the following medical conditions: abdominal obesity, elevated blood pressures, elevated glucose, high t...
Ectopic visceral fat: a clinical and molecular perspective on the cardiometabolic risk [0.03%]
异位内脏脂肪:心血管代谢风险的临床和分子见解
Patrick Mathieu,Marie-Chloé Boulanger,Jean-Pierre Després
Patrick Mathieu
Worldwide, cardiovascular diseases (CVDs) are a leading cause of mortality. While in many westernized societies there has been a decrease prevalence of smoking and that a special emphasis has been put on the urgency to control the, so calle...
Skeletal muscle glucose metabolism and inflammation in the development of the metabolic syndrome [0.03%]
骨骼肌糖代谢与炎症在代谢综合征发病中的作用
André Marette,Ying Liu,Gary Sweeney
André Marette
Insulin resistance and metabolic dysfunction in skeletal muscle play a major role in the development of the metabolic syndrome and type 2 diabetes. Numerous mechanisms have been proposed to explain the pathophysiology of obesity-linked meta...
Mitsuyoshi Takahara,Iichiro Shimomura
Mitsuyoshi Takahara
A clustering of metabolic abnormalities such as dyslipidemia, hypertension, and diabetes mellitus, all of which are major risk factors for cardiovascular disease (CVD), occurs more often than by chance. Numerous epidemiological studies, as ...
Juan G Juárez-Rojas,Gissette Reyes-Soffer,Donna Conlon et al.
Juan G Juárez-Rojas et al.
Autophagy is an essential cellular pathway by which protein aggregates, long-lived proteins, or defective organelles are sequestered in double membrane vesicles and then degraded upon fusion of those vesicles with lysosomes. Although autoph...
Alena Stančáková,Markku Laakso
Alena Stančáková
Metabolic syndrome (MetS) is a cluster of metabolic traits associated with an increased risk of cardiovascular disease and type 2 diabetes mellitus. Central obesity and insulin resistance are thought to play key roles in the pathogenesis of...
Kieren Mather
Kieren Mather
Effects of glucagon like peptide-1 to mediate glycemic effects of weight loss surgery [0.03%]
胰高血糖素样肽-1介导的减肥手术促血糖作用的影响
Marzieh Salehi,David A DAlessio
Marzieh Salehi
To date, weight loss surgeries are the most effective treatment for obesity and glycemic control in patients with type 2 diabetes. Roux-en-Y gastric bypass surgery (RYGB) and sleeve gastrectomy (SG), two widely used bariatric procedures for...