A Genome-Wide Association Study in isolated populations reveals new genes associated to common food likings [0.03%]
孤立人群的全基因组关联研究揭示了新的与常见食物喜好相关的基因
Nicola Pirastu,Maarten Kooyman,Michela Traglia et al.
Nicola Pirastu et al.
Food preferences are the first factor driving food choice and thus nutrition. They involve numerous different senses such as taste and olfaction as well as various other factors such as personal experiences and hedonistic aspects. Although ...
Outcome studies and safety as guide for decision making in treating patients with type 2 diabetes [0.03%]
疗效研究与安全性作为治疗2型糖尿病患者的决策依据
Avivit Cahn,Simona Cernea,Itamar Raz
Avivit Cahn
Cardiovascular disease is the leading cause of mortality in patients with diabetes. Over the past 20 years multiple CV outcome studies have been conducted assessing the cardiovascular benefits of tight glycemic control or of particular gluc...
Exercise resistance across the prediabetes phenotypes: Impact on insulin sensitivity and substrate metabolism [0.03%]
不同糖尿病前期表型的运动阻力：对胰岛素敏感性和底物代谢的影响
Steven K Malin,Zhenqi Liu,Eugene J Barrett et al.
Steven K Malin et al.
Prediabetes is a heterogeneous term that encompasses different origins of insulin resistance and insulin secretion that contribute to distinct patterns of hyperglycemia. In fact, prediabetes is an umbrella term that characterizes individual...
Interventional treatment of obesity and diabetes: An interim report on gastric electrical stimulation [0.03%]
肥胖和糖尿病的介入治疗：胃部电刺激的中期研究报告
Harold E Lebovitz
Harold E Lebovitz
Gastric electrical stimulation has been applied to treat human obesity since 1995. Dilatation of the stomach causes a series of neural reflexes which result in satiation and satiety. In non-obese individuals food ingestion is limited in par...
Jana Engelmann,Ulf Manuwald,Constanze Rubach et al.
Jana Engelmann et al.
We aimed to review and summarize the evidence from accomplished trials analyzing factors influencing mortality in patients with T2DM and to provide some recommendations for targets and treatment in the European region. The following databas...
Perivascular adipose tissue: An unique fat compartment relevant for the cardiometabolic syndrome [0.03%]
血管周围脂肪组织：与心血管代偿综合征有关的独特脂肪组织区间
D I Siegel-Axel,H U Häring
D I Siegel-Axel
Type 2 diabetes and its major risk factor, obesity, are an increasing worldwide health problem. The exact mechanisms that link obesity with insulin resistance, type 2 diabetes, hypertension, cardiovascular complications and renal diseases, ...
Jan Škrha,Jan Šoupal,Jan Škrha Jr et al.
Jan Škrha et al.
Microvascular complications in diabetes are associated with poor long-term diabetes control as measured by HbA1c levels. Glucose fluctuations are related to oxidative stress, endothelial dysfunction, and inflammation, factors traditionally ...
Jens Jordan,Andreas L Birkenfeld
Jens Jordan
Abdominal obesity and elevated blood pressure commonly occur in the same patient and are key components of the metabolic syndrome. However, the association between obesity and increased blood pressure is variable. We review mechanisms linki...
Markolf Hanefeld,Frank Pistrosch,Stefan R Bornstein et al.
Markolf Hanefeld et al.
In ancient Greek medicine the concept of a distinct syndrome (going together) was used to label 'a group of signs and symptoms' that occur together and 'characterize a particular abnormality and condition'. The (dys)metabolic syndrome is a ...
Understanding the metabolic and health effects of low-calorie sweeteners: methodological considerations and implications for future research [0.03%]
了解低卡路里甜味剂的代谢和健康影响：方法学考虑及对未来研究的影响
Allison C Sylvetsky,Jenny E Blau,Kristina I Rother
Allison C Sylvetsky
Consumption of foods, beverages, and packets containing low-calorie sweeteners (LCS) has increased markedly across gender, age, race/ethnicity, weight status, and socio-economic subgroups. However, well-controlled intervention studies rigor...