Pedro Iglesias,María Auxiliadora Bajo,Rafael Selgas et al.
Pedro Iglesias et al.
Thyroid hormones influence renal development, kidney hemodynamics, glomerular filtration rate and sodium and water homeostasis. Hypothyroidism and hyperthyroidism affect renal function by direct renal effects as well as systemic hemodynamic...
Obesity as a risk factor for malignant melanoma and non-melanoma skin cancer [0.03%]
肥胖与恶性黑色素瘤和非黑色素瘤皮肤癌的风险关系
K Karimi,T H Lindgren,C A Koch et al.
K Karimi et al.
The dramatic increases in incidence of both obesity and many cancers including skin cancer emphasize the need to better understand the pathophysiology of both conditions and their connections. Melanoma is considered the fastest growing canc...
Biomarkers of skin aging [0.03%]
皮肤老化的生物标志物
Theodora Kanaki,Evgenia Makrantonaki,Christos C Zouboulis
Theodora Kanaki
Aging is a complex process not only influenced by inherited but also by several environmental factors. It is characterized by a progressive loss of function in multiple tissues, which leads to an increased probability of death. On the other...
Giacomo Tirabassi,Gianmaria Salvio,Barbara Altieri et al.
Giacomo Tirabassi et al.
An emerging branch of research is examining the linkage between Vitamin D and nonskeletal disorders, including endocrine diseases. In this regard, a still little studied aspect concerns the involvement of vitamin D in adrenal gland disorder...
Georgios Nikolakis,Constantine A Stratakis,Theodora Kanaki et al.
Georgios Nikolakis et al.
The skin is an important extra-gonadal steroidogenic organ, capable of metabolizing various hormones from their precursors, as well as of synthesizing de novo a broad palette of sex steroids and glucocorticoids from cholesterol. In this man...
Christos C Zouboulis,Mauro Picardo,Qiang Ju et al.
Christos C Zouboulis et al.
The sebaceous gland is most commonly found in association with a hair follicle. Its traditional function is the holocrine production of sebum, a complex mixture of lipids, cell debris, and other rather poorly characterized substances. Due t...
Hyponatremia and bone disease [0.03%]
低钠血症和骨病
Armando Luis Negri,Juan Carlos Ayus
Armando Luis Negri
Hip fractures represent a serious health risk in the elderly, causing substantial morbidity and mortality. There is now a considerable volume of literature suggesting that chronic hyponatremia increases the adjusted odds ratio (OR) for both...
Low serum vitamin D-status, air pollution and obesity: A dangerous liaison [0.03%]
低维生素D水平、空气污染和肥胖：危险的组合
Luigi Barrea,Silvia Savastano,Carolina Di Somma et al.
Luigi Barrea et al.
The aim of this review is to provide a general overview of the possible associations among the vitamin D status, air pollution and obesity. Sunlight exposure accounts in humans for more than 90 % of the production of vitamin D. Among emergi...
Relapse prediction in Graves´ disease: Towards mathematical modeling of clinical, immune and genetic markers [0.03%]
格雷夫斯病的复发预测：临床标记、免疫标记和遗传标记的数学建模方法研究
Christoph Langenstein,Diana Schork,Klaus Badenhoop et al.
Christoph Langenstein et al.
Problem: Graves' disease (GD) is an important and prevalent thyroid autoimmune disorder. Standard therapy for GD consists of antithyroid drugs (ATD) with treatment periods of around 12 months but relapse is frequent. Sinc...
Csaba P Kovesdy
Csaba P Kovesdy
Hyperkalemia is a frequent clinical abnormality in patients with chronic kidney disease, and it is associated with higher risk of mortality and malignant arrhythmias. Severe hyperkalemia is a medical emergency, which requires immediate ther...