Emerging evidence and potential avenues to achieve durable outcomes in patients with obesity: the confluence of nutrition, and Microbiome on body composition [0.03%]
肥胖患者的持续性结局的最新证据及潜在途径：营养和肠道微生物群在体成分中的汇聚作用
Dra M Isabel T D Correia,Nitin Kapoor,Emma Chávez-Manzanera et al.
Dra M Isabel T D Correia et al.
Obesity is a global health concern that impacts health, quality of life, and longevity in affected individuals. Comorbid cardiovascular disease, type 2 diabetes, cancer, and other conditions often accompany obesity, and researchers are acti...
Body mass index and body composition changes in transgender people undergoing gender-affirming hormone therapy: a systematic review and meta-analysis [0.03%]
性别肯定激素治疗的变性人在体质指数和身体组成方面的变化：一项系统综述和荟萃分析
Ísis Gois,Felipe Behrends Rodrigues,Marcos Pereira et al.
Ísis Gois et al.
Gender-affirming hormone therapy (GAHT) uses sex steroid hormones to induce desired physical changes, improving the quality of life of transgender individuals. While generally considered safe, its effects on body composition and adipose tis...
Hyperphagia in rare melanocortin-4 receptor pathway diseases: therapeutic options and assessing treatment response [0.03%]
罕见黑素皮质素受体4通路疾病患者的摄食过量症状：治疗选择及疗效评估
Jesús Argente,Karine Clément,Jessica Duis et al.
Jesús Argente et al.
Hyperphagia is a hallmark of both congenital and acquired rare melanocortin-4 receptor (MC4R) pathway diseases. Currently, the medical community has no standard treatment guidelines or approach to establishing treatment benefit. This narrat...
Targeted therapeutic strategies as alternative and sustainable treatment options for obesity-induced steatohepatitis [0.03%]
肥胖诱导的steatohepatitis的治疗策略作为替代和可持续的治疗选项
Thendo I Mabuda,Nicole R S Sibuyi,Adewale O Fadaka et al.
Thendo I Mabuda et al.
BBSome: An essential component of hypothalamic regulation of energy homeostasis [0.03%]
BBSome：能量稳态的下丘脑调节的一个重要组成部分
Deng Fu Guo,Yuying Zhao,Connor Laule et al.
Deng Fu Guo et al.
The BBSome is a protein complex composed of eight Bardet-Biedl syndrome (BBS) proteins. Although the BBSome is best known for its role in regulating cilia function, accumulating evidence indicates that this protein complex is also involved ...
Sexual dimorphism in the development and function of the melanocortin system [0.03%]
黑皮质素系统的性别二态性及其发育与功能研究进展
Marc Claret,Roberta Haddad-Tóvolli
Marc Claret
The melanocortin system is fundamental for the regulation of whole-body energy homeostasis. This system consists of pro-opiomelanocortin (POMC) and agouti-related peptide (AgRP) neurons in the arcuate nucleus of the hypothalamus (ARH), as w...
Association between continuous glucose monitoring metrics and cardiovascular autonomic neuropathy in diabetic patients: a systematic review [0.03%]
连续葡萄糖监测指标与糖尿病患者心血管自主神经病变的关系：系统综述
Yifan Jia,Dan Long,Wei Song et al.
Yifan Jia et al.
Cardiovascular autonomic neuropathy (CAN) is a serious and prevalent complication of diabetes, linked to significant morbidity and mortality. Continuous glucose monitoring systems (CGM) provide a comprehensive and continuous glucose profile...
Bandy Chen,Jessica Furtado,Marc Schneeberger
Bandy Chen
The hypothalamus, located at the most ventral part of the brain, is the central regulator of homeostatic processes such as energy balance, autonomic functions, and reproductive regulation via the hypothalamic-pituitary-gonadal axis. The hyp...
Ricardo Rosero-Revelo,Mateo Tamayo,Ricardo Correa et al.
Ricardo Rosero-Revelo et al.
Traditional reliance on Body Mass Index (BMI) as a diagnostic tool for obesity is increasingly challenged due to its inability to differentiate between fat and lean mass and to capture fat distribution. Emerging evidence-including findings ...
Lights or shadows, a promising future for positron emission tomography in pituitary tumors: a systematic review [0.03%]
利与弊：垂体肿瘤领域正电子发射断层扫描展望：系统综述
Sabrina Chiloiro,Carmelo Caldarella,Alessandra Vicari et al.
Sabrina Chiloiro et al.
The diagnosis of pituitary adenomas (PAs), also called pituitary tumors or neuroendocrine tumors (PitNETs) currently involves assessment of blood/plasma hormone levels and traditional neuroradiological techniques, with magnetic resonance im...