Mirjam Christ-Crain
Mirjam Christ-Crain
Arginine Vasopressin (AVP) and copeptin derive from the same precursor molecule. Due to the equimolar secretion, copeptin responds as rapidly as AVP to osmotic, hemodynamic and unspecific stress-related stimuli and both peptides show a very...
Adiponectin and PPAR: a setup for intricate crosstalk between obesity and non-alcoholic fatty liver disease [0.03%]
脂联素和PPAR：肥胖与非酒精性脂肪肝病之间复杂对话的调控机制
Syeda Momna Ishtiaq,Haroon Rashid,Zulfia Hussain et al.
Syeda Momna Ishtiaq et al.
Adiponectin, a soluble adipocytokine, plays an important role in the functioning of adipose tissue and in the regulation of inflammation, particularly hepatic inflammation. The adiponectin subsequently imparts a crucial role in metabolic an...
Vitamin D in physiological and pathological aging: Lesson from centenarians [0.03%]
维生素D在生理和病理老化中的作用：百岁老人研究的启示
Evelyn Ferri,Martina Casati,Matteo Cesari et al.
Evelyn Ferri et al.
Vitamin D is a secosteroid hormone that exerts a pleiotropic action on a wide spectrum of tissues, apparatuses and systems. Thus, vitamin D has assumed an increasingly dominant role as a key determinant of biological mechanisms and specific...
Neuroendocrinological mechanisms underlying impulsive and compulsive behaviors in obesity: a narrative review of fMRI studies [0.03%]
肥胖症中冲动和强迫行为的神经内分泌机制：fMRI研究的叙述性综述
Trevor Steward,Romina Miranda-Olivos,Carles Soriano-Mas et al.
Trevor Steward et al.
Impulsivity and compulsivity are multidimensional constructs that are increasingly considered determinants of obesity. Studies using functional magnetic resonance imaging (fMRI) have provided insight on how differences in brain response dur...
Gut microbiota-derived succinate: Friend or foe in human metabolic diseases? [0.03%]
肠道微生物源的琥珀酸：人体代谢疾病的益友还是敌人？
Sonia Fernández-Veledo,Joan Vendrell
Sonia Fernández-Veledo
There is now a wealth of evidence showing that communication between microbiota and the host is critical to sustain the vital functions of the healthy host, and disruptions of this homeostatic coexistence are known to be associated with a r...
Andrea Palermo,Anda Mihaela Naciu,Gaia Tabacco et al.
Andrea Palermo et al.
Adequate daily calcium intake should normally be achieved by dietary sources. Since low calcium diets are quite common in subjects that do not reach the recommended intake and particularly those at risk of fractures, calcium supplements may...
Saeed Kolahian,Veronika Leiss,Bernd Nürnberg
Saeed Kolahian
Diabetes mellitus is a chronic, progressive, incompletely understood metabolic disorder whose prevalence has been increasing steadily worldwide. Even though little attention has been paid to lung disorders in the context of diabetes, its pr...
Anna Maria Formenti,Francesco Tecilazich,Raffaele Giubbini et al.
Anna Maria Formenti et al.
Parathyroid hormone (PTH) exerts both anabolic and catabolic actions on bone,depending on the duration and periodicity of exposure. Hypoparathyroidism is defined by inadequate production of PTH in the presence oflow serum calcium. In hypopa...
Clinical applications of (epi)genetics in gastroenteropancreatic neuroendocrine neoplasms: Moving towards liquid biopsies [0.03%]
胃肠胰神经内分泌肿瘤的（表）遗传学临床应用：迈向液体活检
Gitta Boons,Timon Vandamme,Marc Peeters et al.
Gitta Boons et al.
High-throughput analysis, including next-generation sequencing and microarrays, have strongly improved our understanding of cancer biology. However, genomic data on rare cancer types, such as neuroendocrine neoplasms, has been lagging behin...
Current perspectives on the impact of clinical disease and biochemical control on comorbidities and quality of life in acromegaly [0.03%]
当前关于肢端肥大症临床疾病和生化控制对并存病及生活质量影响的观点
Federico Gatto,Claudia Campana,Francesco Cocchiara et al.
Federico Gatto et al.
Acromegaly is a rare chronic, systemic disorder caused by excessive growth hormone (GH) secretion from a somatotroph pituitary adenoma. GH hypersecretion leads to overproduction of insulin-like growth factor-1 (IGF-1), which contributes to ...