Endocrine disrupting chemicals: exposure, effects on human health, mechanism of action, models for testing and strategies for prevention [0.03%]
内分泌干扰物:暴露、对人体健康的影响、作用机制、检测模型和预防策略
Bayram Yilmaz,Hakan Terekeci,Suleyman Sandal et al.
Bayram Yilmaz et al.
Endocrine Disrupting Chemicals (EDCs) are a global problem for environmental and human health. They are defined as "an exogenous chemical, or mixture of chemicals, that can interfere with any aspect of hormone action". It is estimated that ...
The gut microbiota modulates both browning of white adipose tissue and the activity of brown adipose tissue [0.03%]
肠道菌群调节白色脂肪组织褐变及棕色脂肪组织活性
José María Moreno-Navarrete,José Manuel Fernandez-Real
José María Moreno-Navarrete
Given the increasing worldwide prevalence of obesity and associated metabolic disturbances, novel therapeutic strategies are imperatively required. A plausible manner to increase energy expenditure is the enhancement of thermogenic pathways...
Endocrine roles of vitamin K-dependent- osteocalcin in the relation between bone metabolism and metabolic disorders [0.03%]
关于骨代谢和代谢障碍之间关系的维生素K依赖性骨钙素的内分泌作用
Ebtesam Abdullah Al-Suhaimi,Meneerah Abdulrahman Al-Jafary
Ebtesam Abdullah Al-Suhaimi
Obesity and diabetes are important metabolic diseases and a major public health problem among the world, they have serious health and economic complications. Overweight and obesity are increased risk for deficiency of vitamin particularly s...
Ghrelin and liver disease [0.03%]
胃饥饿素和肝病
Mar Quiñones,Johan Fernø,Omar Al-Massadi
Mar Quiñones
Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are two of the most common liver diseases associated with obesity, type 2 diabetes and metabolic syndrome. The prevalence of these conditions are increasingl...
Oral microbiota-induced periodontitis: a new risk factor of metabolic diseases [0.03%]
口腔菌群诱导的牙周炎:代谢性疾病的新的风险因素
Matthieu Minty,Thibault Canceil,Matteo Serino et al.
Matthieu Minty et al.
It has recently become evident that the periodontium (gingiva, desmodontal ligament, cementum and alveolar bone) and the associated microbiota play a pivotal role in regulating human health and diseases. The oral cavity is the second larges...
Amanda Cabrera-Mulero,Alberto Tinahones,Borja Bandera et al.
Amanda Cabrera-Mulero et al.
Gut microbiota (GM) is a key contributor to host metabolism and physiology. Data generated on comparing diseased and healthy subjects have reported changes in the GM profile between both health states, suggesting certain bacterial compositi...
Marc Schoeler,Robert Caesar
Marc Schoeler
The gut microbiota is a central regulator of host metabolism. The composition and function of the gut microbiota is dynamic and affected by diet properties such as the amount and composition of lipids. Hence, dietary lipids may influence ho...
Efficacy and safety of very low calorie ketogenic diet (VLCKD) in patients with overweight and obesity: A systematic review and meta-analysis [0.03%]
极低卡路里生酮饮食(VLCKD)治疗超重和肥胖患者的疗效和安全性:系统评价和meta分析
Marco Castellana,Eleonora Conte,Angelo Cignarelli et al.
Marco Castellana et al.
Very low calorie ketogenic diet (VLCKD) has been proposed as a promising option to achieve a significant weight loss in a short time period. We conducted a systematic review and meta-analysis to evaluate its efficacy and safety in patients ...
The gut microbiome and heart failure: A better gut for a better heart [0.03%]
肠道微生物组和心力衰竭:更好的肠道带来更健康的心脏
Maxime Branchereau,Rémy Burcelin,Christophe Heymes
Maxime Branchereau
Despite the development of new drugs and therapeutic strategies, mortality and morbidity related to heart failure (HF) remains high. It is also the leading cause of global mortality. Several concepts have been proposed to explore the underl...
Estelle Grasset,Remy Burcelin
Estelle Grasset
The regulation of glycemia is under a tight neuronal detection of glucose levels performed by the gut-brain axis and an efficient efferent neuronal message sent to the peripheral organs, as the pancreas to induce insulin and inhibit glucago...