Disruption of the GHRH receptor and its impact on children and adults: The Itabaianinha syndrome [0.03%]
GHRH受体功能障碍及其对儿童和成人影响：Itabaianinha综合征
Manuel H Aguiar-Oliveira,Roberto Salvatori
Manuel H Aguiar-Oliveira
Since 1994, we have been studying an extended kindred with 105 subjects (over 8 generations) residing in Itabaianinha County, in the Brazilian state of Sergipe, who have severe isolated GH deficiency (IGHD) due to a homozygous inactivating ...
From microbiota toward gastro-enteropancreatic neuroendocrine neoplasms: Are we on the highway to hell? [0.03%]
从微生物群到胃肠胰神经内分泌肿瘤：我们是否正在通向地狱的高速公路上？
Giovanni Vitale,Alessandra Dicitore,Luigi Barrea et al.
Giovanni Vitale et al.
Gut microbiota is represented by different microorganisms that colonize the intestinal tract, mostly the large intestine, such as bacteria, fungi, archaea and viruses. The gut microbial balance has a key role in several functions. It modula...
A network analysis framework of genetic and nongenetic risks for type 2 diabetes [0.03%]
2型糖尿病遗传和非遗传风险的网络分析框架
Yuan Zhang,Shu Li,Zhi Cao et al.
Yuan Zhang et al.
Both genetic and nongenetic factors have been found to be associated with type 2 diabetes, however, the correlation between them is still unclear. In the present study, we aimed to fully decipher the nongenetic and genetic factor associatio...
Andrea Giustina,Garni Barkhoudarian,Albert Beckers et al.
Andrea Giustina et al.
The 13th Acromegaly Consensus Conference was held in November 2019 in Fort Lauderdale, Florida, and comprised acromegaly experts including endocrinologists and neurosurgeons who considered optimal approaches for multidisciplinary acromegaly...
Yanduan Lin,Ziwei Zhang,Siyu Wang et al.
Yanduan Lin et al.
With the change of life style, glucolipid metabolic disorders (GLMD) has become one of the major chronic disorders causing public health and clinical problems worldwide. Previous studies on GLMD pay more attention to peripheral tissues. In ...
Therapeutic potential of α7 nicotinic acetylcholine receptor agonists to combat obesity, diabetes, and inflammation [0.03%]
激活α7型烟碱乙酰胆碱受体治疗肥胖，糖尿病和炎症的潜力
Han Xie,Natesh Yepuri,Qinghe Meng et al.
Han Xie et al.
The cholinergic anti-inflammatory reflex (CAIR) represents an important homeostatic regulatory mechanism for sensing and controlling the body's response to inflammatory stimuli. Vagovagal reflexes are an integral component of CAIR whose ant...
The role of the Mediterranean diet on weight loss and obesity-related diseases [0.03%]
地中海饮食在体重减轻和肥胖相关疾病中的作用
Ramon Estruch,Emilio Ros
Ramon Estruch
Pandemic obesity is a major public health problem because of its association with non-communicable diseases and all-cause mortality, which can be improved/delayed with weight loss. Thus, several scientific societies and governments have lau...
Dietary weight-loss interventions for the management of obesity in older adults [0.03%]
老年人肥胖体重管理的饮食干预措施
Sabine Goisser,Eva Kiesswetter,Daniel Schoene et al.
Sabine Goisser et al.
The obesity epidemic has reached old age in most industrialized countries, but trials elucidating the benefits and risks of weight reduction in older adults above 70 years of age with obesity remain scarce. While some findings demonstrate a...
Mathilde Simonson,Yves Boirie,Christelle Guillet
Mathilde Simonson
Dietary proteins have been used for years to treat obesity. Body weight loss is beneficial when it concerns fat mass, but loss of fat free mass - especially muscle might be detrimental. This occurs because protein breakdown predominates ove...
Silvia Bettini,Anna Belligoli,Roberto Fabris et al.
Silvia Bettini et al.
The original version of this article unfortunately, has the incorrect title reported in the published paper.