Role of vitamin D in diabetic retinopathy: Pathophysiological and clinical aspects [0.03%]
维生素D在糖尿病视网膜病变中的作用：从病理生理到临床方面
Francesco Tecilazich,Anna Maria Formenti,Andrea Giustina
Francesco Tecilazich
Epidemiological data predict a dramatic increase in the prevalence of diabetes and of diabetic retinopathy (DR) - the most common complication of diabetes-for which however we do not have so far effective tools for prevention and treatment....
Expected and paradoxical effects of obesity on cancer treatment response [0.03%]
肥胖对癌症治疗反应的预期效果和悖论效果
Marco Gallo,Valerio Adinolfi,Viola Barucca et al.
Marco Gallo et al.
Obesity, whose prevalence is pandemic and continuing to increase, is a major preventable and modifiable risk factor for diabetes and cardiovascular diseases, as well as for cancer. Furthermore, epidemiological studies have shown that obesit...
Valentina Guarnotta,Rosario Ferrigno,Marianna Martino et al.
Valentina Guarnotta et al.
The pandemic of coronavirus disease (COVID-19), a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is causing high and rapid morbidity and mortality. Immune system response plays a crucial role in controlling ...
Martin O Savage,Helen L Storr,Philippe F Backeljauw
Martin O Savage
The continuum of growth hormone (GH)-IGF-I axis defects extends from severe to mild GH deficiency, through short stature disorders of undefined aetiology, to GH insensitivity disorders which can also be mild or severe. This group of defects...
Growth hormone and aging [0.03%]
生长激素与衰老
Andrzej Bartke
Andrzej Bartke
Growth hormone (GH) actions impact growth, metabolism, and body composition and have been associated with aging and longevity. Lack of GH results in slower growth, delayed maturation, and reduced body size and can lead to delayed aging, inc...
Overheating or overcooling: heat transfer in the spot to fight against the pandemic obesity [0.03%]
过热或过冷：在应对流行病肥胖的斗争中斑点的热量传递
Leandro Henrique Manfredi
Leandro Henrique Manfredi
The prevalence of obesity has nearly doubled worldwide over the past three and a half decades, reaching pandemic status. Obesity is associated with decreased life expectancy and with an increased risk of metabolic, cardiovascular, nervous s...
M Albertelli,A Dotto,C Di Dato et al.
M Albertelli et al.
Peptide receptor radionuclide therapy (PRRT) has been strengthened since the publication of NETTER-1. Nevertheless, the correct positioning in the therapeutic algorithm is debated, and no optimal sequence has yet been standardized. Possible...
Zvi Laron,Haim Werner
Zvi Laron
Laron Syndrome (LS) [OMIm#262500], or primary GH insensitivity, was first described in 1966 in consanguineous Jewish families from Yemen. LS is characterized by a typical phenotype that includes dwarfism, obesity and hypogenitalism. The dis...
Nicholas A Tritos,Beverly M K Biller
Nicholas A Tritos
In adults, growth hormone (GH) deficiency is associated with increased visceral adiposity, decreased lean body mass, bone mineral density and exercise capacity, dyslipidemia, insulin resistance, increased cardiometabolic and fracture risk, ...
The ultrasound risk stratification systems for thyroid nodule have been evaluated against papillary carcinoma. A meta-analysis [0.03%]
对乳头状癌的甲状腺结节超声风险分层系统的评估。一项荟萃分析
Pierpaolo Trimboli,Marco Castellana,Arnoldo Piccardo et al.
Pierpaolo Trimboli et al.
Thyroid imaging reporting and data systems (TIRADS) are used to stratify the malignancy risk of thyroid nodule by ultrasound (US) examination. We conducted a meta-analysis to evaluate the pooled cancer prevalence and the relative prevalence...