Cardiovascular risk factors in women with previous gestational diabetes mellitus: A systematic review and meta-analysis [0.03%]
妊娠糖尿病妇女的心血管风险因素：系统回顾和-meta分析
Maleesa M Pathirana,Zohra Lassi,Anna Ali et al.
Maleesa M Pathirana et al.
This systematic review and meta-analysis aimed to synthesize evidence on conventional cardiovascular disease (CVD) risk factors among women with previous Gestational Diabetes Mellitus (GDM). The review protocol is registered with PROSPERO (...
Epigenetic regulation of somatostatin and somatostatin receptors in neuroendocrine tumors and other types of cancer [0.03%]
神经内分泌肿瘤及其他类型癌症中生长抑素和生长抑素受体的表观遗传调控
M J Klomp,S U Dalm,M de Jong et al.
M J Klomp et al.
Both somatostatin (SST) and somatostatin receptors (SSTRs) are proteins with important functions in both physiological tissue and in tumors, particularly in neuroendocrine tumors (NETs). NETs are frequently characterized by high SSTRs expre...
Growth hormone deficiency and replacement therapy in adults: Impact on survival [0.03%]
成人生长激素缺乏及替代治疗：对生存的影响
Christa C van Bunderen,Daniel S Olsson
Christa C van Bunderen
In a seminal paper from 1990, Rosen and Bengtsson suggested that hypopituitary patients with a presumed growth hormone (GH) deficiency (GHD) have an excess mortality. Later studies have confirmed this finding but have also shown that the ca...
Molecular prospect of type-2 diabetes: Nanotechnology based diagnostics and therapeutic intervention [0.03%]
二型糖尿病的分子展望：基于纳米技术的诊断和治疗干预
Rout George Kerry,Gyana Prakash Mahapatra,Ganesh Kumar Maurya et al.
Rout George Kerry et al.
About ninety percent of all diabetic conditions account for T2D caused due to abnormal insulin secretion/ action or increased hepatic glucose production. Factors that contribute towards the aetiology of T2D could be well explained through b...
Insights from the clinical phenotype of subjects with Laron syndrome in Ecuador [0.03%]
厄瓜多尔拉龙综合征受试者的临床表型所带来的启示
Jaime Guevara-Aguirre,Camila Bautista,Carlos Torres et al.
Jaime Guevara-Aguirre et al.
The Ecuadorian cohort of subjects with LS has taught us valuable lessons since the late 80's. We have learned about migration of Sephardic Jews to our country, their isolation in remote hamlets and further inbreeding. These geographical, hi...
Jonathan Young,Stephen Bell,Yanrong Qian et al.
Jonathan Young et al.
Growth hormone (GH) induces pleiotropic effects on growth and metabolism via binding and subsequent activation of the growth hormone receptor (GHR) and its downstream signaling pathways. Growth hormone insensitivity (GHI) describes a group ...
Edward O List,Reetobrata Basu,Silvana Duran-Ortiz et al.
Edward O List et al.
Nearly one century of research using growth hormone deficient (GHD) mouse lines has contributed greatly toward our knowledge of growth hormone (GH), a pituitary-derived hormone that binds and signals through the GH receptor and affects many...
Vivian Hwa,Masanobu Fujimoto,Gaohui Zhu et al.
Vivian Hwa et al.
Growth hormone insensitivity (GHI) syndrome, first described in 1966, is classically associated with monogenic defects in the GH receptor (GHR) gene which result in severe post-natal growth failure as consequences of insulin-like growth fac...
Margaret C S Boguszewski
Margaret C S Boguszewski
Growth hormone deficiency (GHD) is a rare but treatable cause of short stature. The diagnosis requires a careful evaluation of clinical history, physical examination and appropriate interpretation of longitudinal growth, with specific featu...
Cesar Luiz Boguszewski
Cesar Luiz Boguszewski
The metabolic actions of growth hormone (GH) last a lifetime and involve several physiological functions associated with the control of body composition, energy metabolism, water regulation, immune response, cardiovascular performance, phys...