Kwang-Mook Jung,Lin Lin,Daniele Piomelli
Kwang-Mook Jung
The endocannabinoid system is found in most, if not all, mammalian organs and is involved in a variety of physiological functions, ranging from the control of synaptic plasticity in the brain to the modulation of smooth muscle motility in t...
Polyphenols and their anti-obesity role mediated by the gut microbiota: a comprehensive review [0.03%]
天然多酚通过肠道微生物群介导的抗肥胖作用:综述一篇文章
Lissette Duarte,Naschla Gasaly,Carlos Poblete-Aro et al.
Lissette Duarte et al.
Obesity is a global public health problem that results in chronic pathologies such as diabetes, cardiovascular diseases, and cancer. The treatment approach based on energy restriction and promotion of physical activity is ineffective in the...
How the love of muscle can break a heart: Impact of anabolic androgenic steroids on skeletal muscle hypertrophy, metabolic and cardiovascular health [0.03%]
肌肉的爱如何伤“心”——合成代谢雄激素类固醇对骨骼肌肥大、代谢和心血管健康的影啊
Deaglan McCullough,Richard Webb,Kevin J Enright et al.
Deaglan McCullough et al.
It is estimated 6.4% of males and 1.6% of females globally use anabolic-androgenic steroids (AAS), mostly for appearance and performance enhancing reasons. In combination with resistance exercise, AAS use increases muscle protein synthesis ...
Modelling gestational diabetes mellitus: large animals hold great promise [0.03%]
妊娠糖尿病模型研究:大型动物大有可为
Xiang Gao,Junsheng He,Anming Zhu et al.
Xiang Gao et al.
Gestational diabetes mellitus (GDM) characterized by hyperglycemia during pregnancy is a risk factor for various maternal and fetal complications. The key pathophysiological mechanisms underlying its development have not been elucidated, la...
Lorenzo Scappaticcio,Fabián Pitoia,Katherine Esposito et al.
Lorenzo Scappaticcio et al.
Coronavirus disease 2019 (COVID-19) is the pandemic of the new millennium. COVID-19 can cause both pulmonary and systemic inflammation, potentially determining multi-organ dysfunction. Data on the relationship between COVID-19 and thyroid h...
Skeletal abnormalities in Hypoparathyroidism and in Primary Hyperparathyroidism [0.03%]
低甲状旁腺素血症和原发性甲旁亢患者的骨骼异常
Barbara C Silva,John P Bilezikian
Barbara C Silva
Both hypoparathyroidism (HypoPT), as well as its pathological counterpart, primary hyperparathyroidism (PHPT), can lead to skeletal abnormalities. Chronic deficiency of PTH in patients with HypoPT is associated with a profound reduction in ...
The experiences of pregnant women with gestational diabetes mellitus: a systematic review of qualitative evidence [0.03%]
妊娠糖尿病孕妇的经历:质性证据的系统回顾研究报告
Jing He,Xiaoli Chen,Yuchen Wang et al.
Jing He et al.
Gestational diabetes mellitus (GDM) can have serious adverse effects on pregnant women and their fetuses. The purpose of this systematic review is to explore responses from women diagnosed with GDM and to describe their real-life experience...
Stefano La Rosa,Silvia Uccella
Stefano La Rosa
Neuroendocrine neoplasms (NENs) are a heterogeneous group of neoplastic proliferations showing different morphological features, immunophenotype, molecular background, clinical presentation, and outcome. They can virtually originate in ever...
Evaluating cost-effectiveness in the management of neuroendocrine neoplasms [0.03%]
神经内分泌肿瘤的治疗成本效益评估
B E White,R Mujica-Mota,T Snowsill et al.
B E White et al.
The rapid evolution of novel, costly therapies for neuroendocrine neoplasia (NEN) warrants formal high-quality cost-effectiveness evaluation. Costs of individual investigations and therapies are high; and examples are presented. We aimed to...
Mojca Jensterle,J Hans DeVries,Tadej Battelino et al.
Mojca Jensterle et al.
Understanding of gustatory coding helps to predict, and perhaps even modulate the ingestive decision circuitry, especially when eating behaviour becomes dysfunctional. Preclinical research demonstrated that glucagon like peptide 1 (GLP-1) i...