Pierpaolo Trimboli,Chiara Camponovo,Lorenzo Scappaticcio et al.
Pierpaolo Trimboli et al.
The coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has the potential to cause multi-organ effects including endocrine disorders. The impact of COVID-19 on the thyroid gland has...
Paula Espinosa-Olarte,Anna La Salvia,Maria C Riesco-Martinez et al.
Paula Espinosa-Olarte et al.
Neuroendocrine neoplasms (NENs) comprise a broad spectrum of tumors with widely variable biological and clinical behavior. Primary tumor site, extent of disease, tumor differentiation and expression of so matostatin receptors, proliferation...
Leptin, the brain and energy homeostasis: From an apparently simple to a highly complex neuronal system [0.03%]
瘦素、大脑和能量平衡：从一个看似简单的神经元系统到一个非常复杂的神经元系统
Margherita Maffei,Antonio Giordano
Margherita Maffei
Leptin, produced and secreted by white adipose tissue in tight relationship with adipose mass, informs the brain about the status of the energy stores serving as the main peripheral signal for energy balance regulation through interaction w...
Autophagy in normal pituitary and pituitary tumor cells and its potential role in the actions of somatostatin receptor ligands in acromegaly [0.03%]
生长激素腺瘤自噬及其在肢端肥大症中作用机制的研究
Giovanni Tulipano,Andrea Giustina
Giovanni Tulipano
Autophagy is an evolutionary conserved process for the self-degradation and recycling of cellular components in the cytoplasm. It is involved in both physiological and pathological conditions. In detail, the term "autophagy" refers to intra...
Imaging of neuroendocrine tumors: A pictorial review of the clinical value of different imaging modalities [0.03%]
神经内分泌肿瘤的影像学检查：不同影像模态临床价值的述评性插图回顾
Ali Pirasteh,Petra Lovrec,Lisa Bodei
Ali Pirasteh
Neuroendocrine tumors (NETs) are multifaceted tumors occurring in a variety of organs and often present as metastatic at the time of diagnosis. Accurate staging is the most significant factor in therapy planning, but it remains a challenge....
Can conditions of skeletal muscle loss be improved by combining exercise with anabolic-androgenic steroids? A systematic review and meta-analysis of testosterone-based interventions [0.03%]
联合使用运动和类固醇能否改善骨骼肌消耗性疾病的状况？基于睾丸激素的干预措施的系统评价和meta分析
Hugo Falqueto,Jorge L R Júnior,Mauro N O Silvério et al.
Hugo Falqueto et al.
Sarcopenia, cachexia, and atrophy due to inactivity and disease states are characterized by a loss of skeletal muscle mass, often accompanied by reduced levels of anabolic hormones (e.g. testosterone). These conditions are associated with a...
Investigation of the Hypothalamo-pituitary-adrenal (HPA) axis: a contemporary synthesis [0.03%]
下丘脑-垂体-肾上腺轴功能研究：现代视角下的整合分析方法学探讨
Zuleyha Karaca,Ashley Grossman,Fahrettin Kelestimur
Zuleyha Karaca
The hypothalamo-pituitary-adrenal (HPA) axis is one of the main components of the stress system. Maintenance of normal physiological events, which include stress responses to internal or external stimuli in the body, depends on appropriate ...
Huan-Ran Zhou,Hong-Yu Kuang
Huan-Ran Zhou
In diabetic patients, diabetic retinopathy (DR) is the leading cause of blindness and seriously affects the quality of life. However, current treatment methods of DR are not satisfactory. Advances have been made in understanding abnormal pr...
Current treatment options and challenges in patients with Type 1 diabetes: Pharmacological, technical advances and future perspectives [0.03%]
1 型糖尿病患者的当前治疗选择和挑战：药物、技术进步及未来展望
Federico Boscari,Angelo Avogaro
Federico Boscari
Type 1 diabetes mellitus imposes a significant burden of complications and mortality, despite important advances in treatment: subjects affected by this disease have also a worse quality of life-related to disease management. To overcome th...
Transplantation of fat tissues and iPSC-derived energy expenditure adipocytes to counteract obesity-driven metabolic disorders: Current strategies and future perspectives [0.03%]
移植脂肪组织和由诱导多能干细胞衍生的耗能脂肪细胞对抗肥胖引起的代谢紊乱：当前策略与未来前景
Vincent Dani,Xi Yao,Christian Dani
Vincent Dani
Several therapeutic options have been developed to address the obesity epidemic and treat associated metabolic diseases. Despite the beneficial effects of surgery and drugs, effective therapeutic solutions have been held back by the poor lo...