Adipogenic progenitors in different organs: Pathophysiological implications [0.03%]
不同器官中的成脂祖细胞：病理生理意义
Francesca Favaretto,Silvia Bettini,Luca Busetto et al.
Francesca Favaretto et al.
In physiological conditions, the adipose organ resides in well-defined areas, where it acts providing an energy supply and as an endocrine organ involved in the control of whole-body energy metabolism. Adipose tissue adipokines connect the ...
Factors influencing the levothyroxine dose in the hormone replacement therapy of primary hypothyroidism in adults [0.03%]
成人原发性甲状腺功能减退激素替代治疗中左旋甲状腺素剂量的影响因素
Philippe Caron,Solange Grunenwald,Luca Persani et al.
Philippe Caron et al.
Levothyroxine (LT4) is a safe, effective means of hormone replacement therapy for hypothyroidism. Here, we review the pharmaceutical, pathophysiological and behavioural factors influencing the absorption, distribution, metabolism and excret...
Setareh Soltani,Kamran Mansouri,Shahram Parvaneh et al.
Setareh Soltani et al.
Diabetes is a chronic disorder characterized by dysregulated glycemic conditions. Diabetic complications include microvascular and macrovascular abnormalities and account for high morbidity and mortality rates in patients. Current clinical ...
Clinical aspects of SARS-CoV-2 infection and vitamin D : COVID-19 and the endocrine system: special issue for reviews in endocrine and metabolic disorders (Felipe Casaneuva, Editor in Chief) A. Giustina and JP Bilezikian, Guest Editors [0.03%]
SARS-CoV-2感染和维生素D的临床方面：COVID-19与内分泌系统 - 《内分泌和代谢障碍评论》特刊（主编Felipe Casaneuva）A. Giustina 和 JP Bilezikian，特邀编辑
Leonardo Bandeira,Marise Lazaretti-Castro,Neil Binkley
Leonardo Bandeira
In December 2019, the first cases of severe acute respiratory syndrome due to a new coronavirus (SARS-Cov-2), later designated as Covid-19, were described in China. With rapid advance of the infection to several continents, in March 2020, W...
Wiktoria Ratajczak,Sarah D Atkinson,Catriona Kelly
Wiktoria Ratajczak
TWEAK (tumor necrosis factor-like weak inducer of apoptosis) is a member of the TNF superfamily that controls a multitude of cellular events including proliferation, migration, differentiation, apoptosis, angiogenesis, and inflammation. TWE...
The role of transforming growth factor beta in thyroid autoimmunity: current knowledge and future perspectives [0.03%]
转化生长因子β在甲状腺自身免疫中的作用：现状与展望
Efstratios Kardalas,Evangelos Sakkas,Marek Ruchala et al.
Efstratios Kardalas et al.
The complex mechanisms, which are related to the pathophysiology and the development of autoimmune thyroid diseases, involve transforming growth factor beta (TGF-β) and its interplay with the immune system. The aim of this review is to exa...
Catalina Picó,Mariona Palou,Catalina Amadora Pomar et al.
Catalina Picó et al.
Leptin is a hormone primarily produced by the adipose tissue in proportion to the size of fat stores, with a primary function in the control of lipid reserves. Besides adipose tissue, leptin is also produced by other tissues, such as the st...
Zhongqin Gong,Hao Jia,Lingbin Xue et al.
Zhongqin Gong et al.
Transcription factor FOXP3 is a crucial regulator in the development and function of regulatory T cells (Treg) that are essential for immunological tolerance and homeostasis. Numerous studies have indicated the correlation of tumor infiltra...
Farah Meah,Michelle Lundholm,Nicholas Emanuele et al.
Farah Meah et al.
With the increase in cannabis use due to policy changes and areas of decriminalization, it is important to recognize the potential impact of these substances on endocrine processes. Cannabinoids have many effects by activating the endocanna...
Silvia Vannuccini,Sara Clemenza,Margherita Rossi et al.
Silvia Vannuccini et al.
Endometriosis is a benign uterine disorder characterized by menstrual pain and infertility, deeply affecting women's health. It is a chronic disease and requires a long term management. Hormonal drugs are currently the most used for the med...