Hypothalamic actions of estrogens in the regulation of energy and glucose homeostasis [0.03%]
雌激素在能量和葡萄糖稳态调节中的下丘脑作用
Ismael González-García,Yong Xu
Ismael González-García
Estrogens are a group of steroid hormones that exert a key role in female sexual and reproductive development and function. Produced primarily in the ovaries, estrogens influence many different aspects of physiology such as temperature home...
Thierry Brue,Philippe Chanson,Delphine Drui et al.
Thierry Brue et al.
From identity to function: unveiling the cellular complexity of hypothalamic feeding circuits [0.03%]
从身份到功能：揭开下丘脑摄食回路细胞复杂性的面纱
Sheridan H Littleton,John A Tadross,Giles S H Yeo
Sheridan H Littleton
The hypothalamus is arguably the most complex part of the brain, with the greatest heterogeneity of cellular populations. It is an integration center for peripheral signals and external stimuli and plays a key role in coordinating a myriad ...
Metabolic reprogramming in diabetes and other endocrine and metabolic disorders: exploring the Warburg effect, ketones, and SGLT2 inhibitors [0.03%]
糖尿病及其他内分泌和代谢障碍中的代谢重构：探索瓦堡效应、酮体及SGLT2抑制剂
Pedro Carrera-Bastos,Marcel H A Muskiet,Fernando Mata-Ordoñez et al.
Pedro Carrera-Bastos et al.
The "Warburg effect", a metabolic adaptation observed in dividing cells, involves a shift from mitochondrial oxidative phosphorylation to cytoplasmic glucose metabolism. This metabolic process is characterized by increased cellular uptake o...
Bridging the gap: recommendations to accomplish transition from pediatric to adult care in adolescents living with obesity [0.03%]
跨越鸿沟：促进肥胖青少年从儿科转至成人期医疗护理的建议
Albert Goday,Gilberto Pérez,Amanda Fernández et al.
Albert Goday et al.
Childhood obesity is a significant concern and its chronic nature results in an increased risk of adulthood obesity. Poorly planned transition from pediatric to adult care may contribute to poor outcomes. Failed transition may result in los...
Hypothalamic control of puberty: from neuronal circuits to mechanisms for its metabolic regulation [0.03%]
下丘脑控制青春期：从神经环路到代谢调控机制
Manuel Jimenez-Puyer,Verónica Sobrino,William H Colledge et al.
Manuel Jimenez-Puyer et al.
The hypothalamus is a singular brain region with essential roles in the control of a wide diversity of vegetative functions, from growth and energy balance to reproduction. These processes are governed by interconnected neuroendocrine pathw...
Longitudinal dynamics of impulsivity in individuals undergoing obesity surgery - a systematic review [0.03%]
减肥手术患者的冲动性纵向动态变化：系统综述
Katrin Elisabeth Giel,Lucia Camacho-Barcia,Laura Schultze-Rhonhof et al.
Katrin Elisabeth Giel et al.
Impulsivity is a personality trait composed of (food) reward sensitivity and inhibitory control. We have systematically synthesized evidence from prospective studies on broadly conceptualized impulsivity as agent and/or object of change wit...
Aleksandra Mrowiec,Teresa Kasprzyk-Kucewicz,Daria Wziątek-Kuczmik et al.
Aleksandra Mrowiec et al.
Diabetic foot ulcers (DFUs) are among the most serious complications of diabetes mellitus, often resulting in infection, amputation, and increased mortality. Early detection is essential but remains difficult due to the complex interaction ...
Hypothalamic ceramide metabolism in obesity and dysregulation of glucose homeostasis [0.03%]
肥胖与糖代谢紊乱中的下丘脑类脂胺代谢研究
Hervé Le Stunff,Paloma Brasilio Villalta,Christophe Magnan
Hervé Le Stunff
The central nervous system is a key regulator of energy and glucose homeostasis, integrating peripheral signals such as hormones and nutrients to maintain metabolic balance. Among its regions, the hypothalamus plays a central role in monito...
Hypothalamic astrocytes: connecting brain and periphery in metabolic control [0.03%]
下丘脑星形胶质细胞：在代谢控制中连接大脑和外周
Ophélia Le Thuc,Franziska M Lechner,Cristina García-Cáceres
Ophélia Le Thuc
Astrocytes, once viewed primarily as supportive cells in the central nervous system, are increasingly recognized as dynamic regulators in the regulation of systemic metabolism, especially within the hypothalamus. Recent research highlights ...