Variable phenotypes of individual and family monogenic cases with hyperinsulinism and diabetes: a systematic review [0.03%]
单基因发病的高胰岛素血症和糖尿病个体及家庭的变异表型:系统性回顾
Kevin Perge,Marc Nicolino
Kevin Perge
Maturity-Onset Diabetes of the Youth (MODY) diabetes remains commonly misdiagnosed. A monogenic form should be suspected in individuals presenting hyperinsulinemic hypoglycemia (HH) associated with, either later development of MODY (hypogly...
Cognitive deficits in primary hyperparathyroidism - what we know and what we do not know: A narrative review [0.03%]
原发性甲状旁腺功能亢进的认知障碍:我们所知与未知——综述文章
Manju Chandran,Lydia Tan Li Yeh,Mechteld C de Jong et al.
Manju Chandran et al.
Classic symptoms of primary hyperparathyroidism (PHPT) are seen in approximately 20% of patients. While features such as kidney stones and skeletal disease are often highlighted as directly related to the disease, others can be even more pr...
Endocrinological and inflammatory markers in individuals with spinal cord injury: A systematic review and meta-analysis [0.03%]
脊髓损伤个体的内分泌学和炎症标志物:系统回顾和荟萃分析
Gabriela Boehl,Peter Francis Raguindin,Ezra Valido et al.
Gabriela Boehl et al.
Spinal cord injury (SCI) can lead to dramatic physiological changes which can be a factor in developing secondary health conditions and might be reflected in biomarker changes in this elevated risk group. We focused specifically on the endo...
Effect of resistance training on bioelectrical phase angle in older adults: a systematic review with Meta-analysis of randomized controlled trials [0.03%]
阻力训练对老年人生物电相位角影响的系统评价和 meta 分析
Francesco Campa,Lucas Antonio Colognesi,Tatiana Moro et al.
Francesco Campa et al.
Resistance training has been proposed as a valid practice to counteract the aging effect on body mass and its components, which can be easily evaluated though the bioelectrical impedance analysis. This study aimed to achieve a systematic re...
Bone health in ageing men [0.03%]
老年男性骨骼健康问题
Karel David,Nick Narinx,Leen Antonio et al.
Karel David et al.
Osteoporosis does not only affect postmenopausal women, but also ageing men. The burden of disease is projected to increase with higher life expectancy both in females and males. Importantly, osteoporotic men remain more often undiagnosed a...
A new era for oral peptides: SNAC and the development of oral semaglutide for the treatment of type 2 diabetes [0.03%]
口服肽的新时代:SNAC和口服司美格鲁肽治疗2型糖尿病的发展
Vanita R Aroda,Lawrence Blonde,Richard E Pratley
Vanita R Aroda
Glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs) were first introduced for the treatment of type 2 diabetes (T2D) in 2005. Despite the high efficacy and other benefits of GLP-1RAs, their uptake was initially limited by the fact ...
Gary Wittert,Mathis Grossmann
Gary Wittert
In the absence of obesity, adverse lifestyle behaviours, and use of medication such as opioids serum testosterone concentrations decrease by only a minimal amount at least until very advanced age in most men. Obesity is heterogeneous in its...
Adrenal insufficiency in pregnancy: Physiology, diagnosis, management and areas for future research [0.03%]
妊娠期肾上腺功能不全:生理、诊断、治疗及未来研究方向
Jessica H Lee,David J Torpy
Jessica H Lee
Adrenal insufficiency requires prompt diagnosis in pregnancy, as untreated, it can lead to serious consequences such as adrenal crisis, intrauterine growth restriction and even foetal demise. Similarities between symptoms of adrenal insuffi...
Patient-reported outcome measures for assessing health-related quality of life in people with type 2 diabetes: A systematic review [0.03%]
用于评估2型糖尿病患者健康相关生活质量的患者报告结果测量工具:系统评价
Marlous Langendoen-Gort,Lenka Groeneveld,Cecilia A C Prinsen et al.
Marlous Langendoen-Gort et al.
Patient-Reported Outcome Measures (PROMs) are important tools to assess outcomes relevant to patients, with Health-Related Quality Of Life (HRQOL) as an important construct to be measured. Many different HRQOL PROMs are used in the type 2 d...
Paula Espinosa-Olarte,Anna La Salvia,Maria C Riesco-Martinez et al.
Paula Espinosa-Olarte et al.