Rare forms of genetic paediatric adrenal insufficiency: Excluding congenital adrenal hyperplasia [0.03%]
罕见的遗传性儿童肾上腺功能不全形式：非先天性肾上腺增生型
Valeria Hasenmajer,Rosario Ferrigno,Marianna Minnetti et al.
Valeria Hasenmajer et al.
Adrenal insufficiency (AI) is a severe endocrine disorder characterized by insufficient glucocorticoid (GC) and/or mineralocorticoid (MC) secretion by the adrenal glands, due to impaired adrenal function (primary adrenal insufficiency, PAI)...
Luís B Sardinha,Gil B Rosa
Luís B Sardinha
The biophysical response of the human body to electric current is widely appreciated as a barometer of fluid distribution and cell function. From distinct raw bioelectrical impedance (BIA) variables assessed in the field of body composition...
Leigh C Ward,Steven Brantlov
Leigh C Ward
Measurement of phase angle using bioimpedance analysis (BIA) has become popular as an index of so-called "cellular health". What precisely is meant by this term is not always clear but strong relationships have been found between cellular w...
Amanda Casirati,Silvia Crotti,Alessandro Raffaele et al.
Amanda Casirati et al.
Diseases of the liver and the digestive system can lead to malnutrition through an action of reduced food intake or nutrient use, inflammation and impaired metabolism, which result in substantial changes in body composition. Frequently, mal...
Mechanistic insights of soluble uric acid-induced insulin resistance: Insulin signaling and beyond [0.03%]
可溶性尿酸诱导的胰岛素抵抗的作用机制研究：胰岛素信号转导及其他方面
Wei Yu,De Xie,Tetsuya Yamamoto et al.
Wei Yu et al.
Hyperuricemia is a metabolic disease caused by purine nucleotide metabolism disorder. The prevalence of hyperuricemia is increasing worldwide, with a growing trend in the younger populations. Although numerous studies have indicated that hy...
Mitochondrial epigenetic modifications and nuclear-mitochondrial communication: A new dimension towards understanding and attenuating the pathogenesis in women with PCOS [0.03%]
线粒体表观遗传修饰和核质通讯：理解及缓解多囊卵巢综合征女性发病机制的新维度
Pallavi Shukla,Girish C Melkani
Pallavi Shukla
Mitochondrial DNA (mtDNA) epigenetic modifications have recently gained attention in a plethora of complex diseases, including polycystic ovary syndrome (PCOS), a common cause of infertility in women of reproductive age. Herein we discussed...
Phase angle in assessment and monitoring treatment of individuals with respiratory disease [0.03%]
呼吸疾病个体治疗评估和监测中的相位角评估
Fernando De Benedetto,Stefano Marinari,Francesco De Blasio
Fernando De Benedetto
Phase angle (PhA) represents a raw variable measured with bioelectrical impedance analysis (BIA) that is used to assess malnutrition in many diseases, including respiratory diseases, mainly chronic obstructive pulmonary disease (COPD). COPD...
Manal A Abbas,Noor Nadhim Al-Saigh,Fadi G Saqallah
Manal A Abbas
Milk is a rich source of miRNA packaged in exosomes. Evidence for the systemic uptake and tissue distribution of milk exosomes was reported in newborn and adult humans and animals. Breastfeeding in infants was associated with a reduced risk...
The immune microenviroment in somatotropinomas: from biology to personalized and target therapy [0.03%]
生长激素瘤的免疫微环境：从生物学角度到个性化和针对性治疗
Sabrina Chiloiro,Laura De Marinis
Sabrina Chiloiro
Pituitary tumors are rare neoplasms, with a heterogeneous biological and clinical behavior, due to their clinical course, local invasive growth, resistance to conventional therapies and the risk of disease progression. Recent studies on tum...
The diagnosis and management of pheochromocytoma and paraganglioma during pregnancy [0.03%]
妊娠期间嗜铬细胞瘤和副神经节瘤的诊断与管理
Roderick J Clifton-Bligh
Roderick J Clifton-Bligh
Diagnosis of pheochromocytoma or paraganglioma (PPGL) in pregnancy has been associated historically with high rates of materno-fetal morbidity and mortality. Recent evidence suggests outcomes are improved by recognition of PPGL before or du...