Julie Refardt,Cihan Atila,Mirjam Christ-Crain
Julie Refardt
Arginine vasopressin deficiency (AVP-D) is one of the main entities of the polyuria-polydipsia syndrome. Its correct diagnosis and differentiation from the other two causes - AVP resistance and primary polydipsia - is crucial as this determ...
Role of CaMKII in diabetes induced vascular injury and its interaction with anti-diabetes therapy [0.03%]
钙调神经磷酸酶在糖尿病血管损伤中的作用及其与降糖治疗的相互作用研究
Stephanie Chacar,Abdulhamid Abdi,Khalifa Almansoori et al.
Stephanie Chacar et al.
Diabetes mellitus is a metabolic disorder denoted by chronic hyperglycemia that drives maladaptive structural changes and functional damage to the vasculature. Attenuation of this pathological remodeling of blood vessels remains an unmet ta...
New findings on brain actions of growth hormone and potential clinical implications [0.03%]
生长激素的脑作用的新发现及其潜在的临床意义
Jose Donato Jr,John J Kopchick
Jose Donato Jr
Growth hormone (GH) is secreted by somatotropic cells of the anterior pituitary gland. The classical effects of GH comprise the stimulation of cell proliferation, tissue and body growth, lipolysis, and insulin resistance. The GH receptor (G...
Potential therapeutic strategies for osteoarthritis via CRISPR/Cas9 mediated gene editing [0.03%]
通过CRISPR / Cas9介导的基因编辑治疗骨关节炎的潜在策略
Rexhina Vlashi,Xingen Zhang,Haibo Li et al.
Rexhina Vlashi et al.
Osteoarthritis (OA) is an incapacitating and one of the most common physically degenerative conditions with an assorted etiology and a highly complicated molecular mechanism that to date lacks an efficient treatment. The capacity to design ...
An update on the secretory functions of brown, white, and beige adipose tissue: Towards therapeutic applications [0.03%]
棕色、白色和米色脂肪组织分泌功能的最新研究进展及其潜在治疗应用
Zeinab Ghesmati,Mohsen Rashid,Shabnam Fayezi et al.
Zeinab Ghesmati et al.
Adipose tissue, including white adipose tissue (WAT), brown adipose tissue (BAT), and beige adipose tissue, is vital in modulating whole-body energy metabolism. While WAT primarily stores energy, BAT dissipates energy as heat for thermoregu...
Efficacy and tolerability of somatostatin analogues according to gender in patients with neuroendocrine tumors [0.03%]
性别影响生长抑素类似物治疗神经内分泌肿瘤的有效性和耐受性吗？
Rosaria M Ruggeri,Irene Aini,Stefano Gay et al.
Rosaria M Ruggeri et al.
As the incidence of neuroendocrine tumors has been rising, gender differences in epidemiology and clinical behavior have emerged, and interest into a gender-driven management of these tumors has grown with the aim to improve survival and qu...
Association between protein undernutrition and diabetes: Molecular implications in the reduction of insulin secretion [0.03%]
蛋白质营养不良与糖尿病的相关性：对胰岛素分泌减少的分子影响
Thiago Dos Reis Araujo,Bruna Lourençoni Alves,Lohanna Monali Barreto Dos Santos et al.
Thiago Dos Reis Araujo et al.
Undernutrition is still a recurring nutritional problem in low and middle-income countries. It is directly associated with the social and economic sphere, but it can also negatively impact the health of the population. In this sense, it is ...
Fabian Pitoia,Pierpaolo Trimboli
Fabian Pitoia
The prevalence of thyroid disease continues to rise. As a consequence, the research in the thyroid field has significantly increased over time. Thus, clinicians, and endocrinologists first, have to be aware of the important continuous progr...
Epigenetic programming for obesity and noncommunicable disease: From womb to tomb [0.03%]
表观遗传学编程与肥胖和非传染性疾病：从胎儿到死亡
Lucas Paulo Jacinto Saavedra,Silvano Piovan,Veridiana Mota Moreira et al.
Lucas Paulo Jacinto Saavedra et al.
Several epidemiological, clinical and experimental studies in recent decades have shown the relationship between exposure to stressors during development and health outcomes later in life. The characterization of these susceptible phases, s...
Erika Abelleira,Fernando Jerkovich
Erika Abelleira
The current approach for patients with differentiated thyroid carcinoma should be individualized according to the risk of recurrence, and this stratification could be used to identify the risk of persistent/recurrent disease in three scenar...