Bryan Padraig Finn,Mehul T Dattani
Bryan Padraig Finn
Hypoprolactinaemia is an endocrinopathy which is typically encountered as part of a combined pituitary hormone deficiency picture. The vast majority of genetic causes identified to date have been in the context of congenital hypopituitarism...
The homeo-FIT-prolactin hypothesis: the role of prolactin in metabolic homeostasis - association or causality? [0.03%]
同源-FIT-催乳素假说：催乳素在代谢稳态中的作用-关联或因果关系？
Jesper Krogh
Jesper Krogh
The homeo-fit-prolactin hypothesis proposes a causal metabolic role for prolactin with hypoprolactinemia and hyperprolactinemia leading to adverse metabolic alterations. However, prolactin within the normal range and up to four times the up...
Clinical research progress on β-cell dysfunction in T2DM development in the Chinese population [0.03%]
我国糖尿病患者β细胞功能障碍的临床研究进展
Yibing Chen,Qian Jiang,Xiaowei Xing et al.
Yibing Chen et al.
The prevalence of type-2 diabetes mellitus (T2DM) has increased over 10-fold in the past 40 years in China, which now has the largest T2DM population in the world. Insulin resistance and β-cell dysfunction are the typical features of T2DM....
Agnieszka Siejka,Hanna Lawnicka,Saikat Fakir et al.
Agnieszka Siejka et al.
GHRH is a neuropeptide associated with a diverse variety of activities in human physiology and immune responses. The present study reviews the latest information on the involvement of GHRH in the immune system and inflammation, suggesting t...
Replacement with sex steroids in hypopituitary men and women: implications for gender differences in morbidities and mortality [0.03%]
生长激素缺乏成人使用性激素替代治疗的性别差异对并发症和死亡率的影响
Darran Mc Donald,Tara McDonnell,Michael W O&#x;Reilly et al.
Darran Mc Donald et al.
Hypopituitarism is a heterogenous disorder characterised by a deficiency in one or more anterior pituitary hormones. There are marked sex disparities in the morbidity and mortality experienced by patients with hypopituitarism. In women with...
Prolactin deficiency in the context of other pituitary hormone abnormalities : Special issue: hypoprolactinemia: a neglected endocrine disorder [0.03%]
泌乳素缺乏及相关垂体激素异常：特刊：低泌乳素血症：一个被忽视的内分泌紊乱疾病
Ilan Shimon
Ilan Shimon
Prolactin deficiency is rare. It generally occurs when pituitary disorders, such as large pituitary tumors, pituitary apoplexy, and other conditions associated with sellar mass effect lead to global failure of pituitary function and hypopit...
Vitamin D and hip protectors in osteosarcopenia: a combined hip fracture preventing approach [0.03%]
防治骨质疏松和少肌症的维生素D和髋部保护垫：一种联合预防髋部骨折的方法
Alessandro Giustina,Andrea Giustina
Alessandro Giustina
Osteosarcopenia is an emerging clinical condition highly prevalent in the older people. Affected subjects due to their intrinsic skeletal fragility and propensity to falls are at elevated risk of hip fractures which can increase morbidity a...
Continuous glucose monitoring in patients with inherited metabolic disorders at risk for Hypoglycemia and Nutritional implications [0.03%]
遗传性代谢病患者的持续葡萄糖监测及营养影响
Giorgia Gugelmo,Evelina Maines,Federico Boscari et al.
Giorgia Gugelmo et al.
Managing Inherited Metabolic Disorders (IMDs) at risk for hypoglycemia, such as Glycogen Storage Diseases (GSDs), Hereditary Fructose Metabolism Disorders (HFMDs) and Congenital Hyperinsulinism (CH), poses challenges in dietary treatments a...
Adriana G Ioachimescu,Fahrettin Kelestimur
Adriana G Ioachimescu
Prolactin levels can be influenced by multiple medications primarily through the interaction with dopamine receptors which regulate its secretion. Unlike hyperprolactinemia which has a well-defined clinical phenotype, the effects of hypopro...
The role of tissue oxygenation in obesity-related cardiometabolic complications [0.03%]
组织氧合在肥胖相关心血管代谢并发症中的作用
Geng Li,Ruth C R Meex,Gijs H Goossens
Geng Li
Obesity is a complex, multifactorial, chronic disease that acts as a gateway to a range of other diseases. Evidence from recent studies suggests that changes in oxygen availability in the microenvironment of metabolic organs may exert an im...