Anti-inflammatory effects of tirzepatide: a systematic review and meta-analysis [0.03%]
tirzepatide的抗炎作用：系统评价和荟萃分析
Walter Masson,Martín Lobo,Juan P Nogueira et al.
Walter Masson et al.
Tirzepatide, a dual GIP and GLP-1 receptor agonist, has shown significant metabolic benefits and weight reduction, but its anti-inflammatory effects have been less studied. This study was conducted in accordance with PRISMA guidelines, incl...
Beyond satiety: unraveling the complex roles of POMC neurons in behavior and metabolism [0.03%]
超越饱腹感：揭秘POMC神经元在行为和代谢中的复杂作用
Victor Jouque,Cristina Miralpeix,Antonio J López-Gambero et al.
Victor Jouque et al.
Hypothalamic pro-opiomelanocortin (POMC) neurons are classically viewed as mediators of satiety, acting in response to metabolic and hormonal cues and in opposition to Agouti-related protein (AgRP) neurons to maintain energy balance. This m...
Emerging role of AgRP neurons as integrators of metabolic, sensory and environmental cues in the control of energy homeostasis [0.03%]
Agouti相关蛋白神经元在能量平衡调控中整合代谢、感觉和环境信号的作用机制及其新兴作用研究进展
Maya Faour,Nour Mesto,Claire Martin et al.
Maya Faour et al.
The regulation of energy homeostasis is an essential function of every living organism. In mammals a complex interplay of neural networks has evolved to ensure proper adaptation to energy demands, availability, consumption, storage and util...
Body composition changes across a spectrum of hypothyroidism severity - a systematic review and meta-analysis [0.03%]
不同程度甲状腺功能减退症体成分变化的系统评价和meta分析
Derrick Kretli-Souza,Nathalia Elizabete Paulino,Raiane Aparecida Asevedo et al.
Derrick Kretli-Souza et al.
This systematic review and meta-analysis aimed to investigate the impact of clinical hypothyroidism (CH) and subclinical hypothyroidism (SCH) on anthropometric parameters, such as body mass index (BMI), body weight (BW), waist circumference...
Management of cushing's syndrome in patients with adrenocortical cancer: state of the art and future perspectives [0.03%]
库欣综合征伴肾上腺皮质癌患者的管理：现状与未来展望
Valentina Guarnotta,Antonio Stigliano,Massimo Terzolo et al.
Valentina Guarnotta et al.
Adrenocortical cancers (ACCs) are rare tumours, with up to 50% of cases associated with hypercortisolism. Cortisol-secreting ACCs are characterized by a worse prognosis, and in these patients, the normalization of hypercortisolism is mandat...
Looking beyond fat in obesity: the frequently overlooked importance of muscle mass [0.03%]
展望肥胖问题中被经常忽略的肌肉量的重要性：超越脂肪看肥胖问题
Refaat Hegazi,Bruno Halpern
Refaat Hegazi
Obesity is traditionally defined as "abnormal or excessive fat accumulation that presents a health risk," yet this definition lacks precision and fails to account for individual variability in body composition. The continued reliance on bod...
Trends in gestational diabetes prevalence in China from 1990 to 2024: a systematic review and meta-analysis [0.03%]
中国1990至2024年妊娠糖尿病患病率变化趋势：系统综述和荟萃分析
Xiaodong Wu,Henning Tiemeier,Tingting Xu
Xiaodong Wu
This study examines the 34-year trends in gestational diabetes mellitus (GDM) prevalence in China, analyzing diagnostic shifts, regional variations, and urban-rural disparities. A comprehensive search of PubMed, Scopus, EMBASE, Google Schol...
Endocrine and metabolic consequences of childhood-onset craniopharyngioma during the transition age: A literature review by the TALENT study group [0.03%]
青春期鞍区肿瘤患儿内分泌代谢的临床转归及相关影响因素的研究进展
Dario De Alcubierre,Tiziana Feola,Giulia Puliani et al.
Dario De Alcubierre et al.
Craniopharyngiomas are frequently diagnosed during childhood and adolescence, crucial periods for physical and psychosocial development. Despite improvements in survival rates, patients with childhood-onset craniopharyngioma face a wide arr...
Emerging evidence and potential avenues to achieve durable outcomes in patients with obesity: the confluence of nutrition, and Microbiome on body composition [0.03%]
肥胖患者的持续性结局的最新证据及潜在途径：营养和肠道微生物群在体成分中的汇聚作用
Dra M Isabel T D Correia,Nitin Kapoor,Emma Chávez-Manzanera et al.
Dra M Isabel T D Correia et al.
Obesity is a global health concern that impacts health, quality of life, and longevity in affected individuals. Comorbid cardiovascular disease, type 2 diabetes, cancer, and other conditions often accompany obesity, and researchers are acti...
Body mass index and body composition changes in transgender people undergoing gender-affirming hormone therapy: a systematic review and meta-analysis [0.03%]
性别肯定激素治疗的变性人在体质指数和身体组成方面的变化：一项系统综述和荟萃分析
Ísis Gois,Felipe Behrends Rodrigues,Marcos Pereira et al.
Ísis Gois et al.
Gender-affirming hormone therapy (GAHT) uses sex steroid hormones to induce desired physical changes, improving the quality of life of transgender individuals. While generally considered safe, its effects on body composition and adipose tis...