Correction to: Network‑Based Integrated Analysis of Transcriptomic Studies in Dissecting Gene Signatures for LPS‑Induced Acute Lung Injury [0.03%]
纠正:网络基础的转录组学研究整合分析在分解LPS诱导的急性肺损伤的基因标志物中的应用
Fang Cao,Chunyan Wang,Danling Long et al.
Fang Cao et al.
Published Erratum
Inflammation. 2022 Apr;45(2):929. DOI:10.1007/s10753-021-01584-y 2022
The Role of IL-27 in the Systemic Inflammatory Response That Accompanies Preterm Labour [0.03%]
IL-27在早产相关全身炎症反应中的作用
Youwen Mei,Yuxin Ran,Zheng Liu et al.
Youwen Mei et al.
This study aimed to investigate whether interleukin-27 (IL-27) activates maternal peripheral blood mononuclear cells (PBMCs) and induces inflammatory responses in amniotic epithelial cells in preterm labour (PL). The expression of IL-27p28,...
Amelioration of Neuropathic Pain and Attenuation of Neuroinflammation Responses by Tetrahydropalmatine Through the p38MAPK/NF-κB/iNOS Signaling Pathways in Animal and Cellular Models [0.03%]
四氢帕马丁通过p38MAPK/NF-κB/iNOS信号通路改善动物和细胞模型中的神经病理性疼痛及减弱神经炎症反应
Cheng Hu,Menglin He,Meijuan Chen et al.
Cheng Hu et al.
Neuropathic pain (NP) treatment remains a challenge because the pathomechanism is not yet fully understood. Because of low treatment efficacy, there is an important unmet need in neuropathic pain patients, and the development of a more effe...
Follistatin-Like 1 Induces the Activation of Type 2 Innate Lymphoid Cells to Promote Airway Inflammation in Asthma [0.03%]
卵白素生成素类似物1通过激活第二型固有淋巴细胞来促进哮喘的气道炎症反应
Siyuan Huang,Rong Zeng,Jing Wang et al.
Siyuan Huang et al.
Asthma is a chronic disease closely related to airway inflammation. It has been proven that type 2 innate lymphoid cells (ILC2s) play an essential role in airway inflammation in asthma. Furthermore, there is growing evidence that Follistati...
Ganoderic Acid A Attenuates IL-1β-Induced Inflammation in Human Nucleus Pulposus Cells Through Inhibiting the NF-κB Pathway [0.03%]
通过抑制NF-κB通路,灵芝酸A减轻人椎间盘细胞IL-1β诱导的炎症反应
Sihua Zheng,Jianmin Ma,Xuezheng Zhao et al.
Sihua Zheng et al.
Intervertebral disc (IVD) degeneration is a major cause of low back pain associated with several pathological changes in the IVD, including dysfunction of nucleus pulposus (NP) cells. Ganoderic Acid A (GAA), one of triterpenoid extracts of ...
TLR4-IN-C34 Inhibits Lipopolysaccharide-Stimulated Inflammatory Responses via Downregulating TLR4/MyD88/NF-κB/NLRP3 Signaling Pathway and Reducing ROS Generation in BV2 Cells [0.03%]
TLR4-IN-C34通过下调TLR4/MyD88/NF-κB/NLRP3信号通路和减少ROS的产生来抑制脂多糖刺激的小胶质细胞BV2炎症反应
Shan-Shan Zhang,Man Liu,Dong-Ni Liu et al.
Shan-Shan Zhang et al.
TLR4 signal activated by lipopolysaccharide (LPS) is involved in the pathological process of the central nervous system (CNS) diseases and the suppression of TLR4 signal may become an effective treatment. TLR4-IN-C34, a TLR4 inhibitor, is e...
Neutrophil Extracellular Trap Formation Potential Correlates with Lung Disease Severity in COVID-19 Patients [0.03%]
中性粒细胞外陷阱形成潜能与COVID-19患者肺部疾病严重程度相关
Nedha Kinnare,Jessica S Hook,Parth A Patel et al.
Nedha Kinnare et al.
Severe lung inflammation is common in life-threatening coronavirus disease 2019 (COVID-19). This study tested the hypothesis that polymorphonuclear (PMN, neutrophil) phenotype early in the course of disease progression would predict peak lu...
Multiplex Immunofluorescence for Detection of Spatial Distributions of Infiltrating T Cells Within Different Regions of Hepatic Lobules During Liver Transplantation Rejection [0.03%]
多重免疫荧光检测肝移植排斥过程中不同肝小叶区域浸润T细胞的空间分布
Shi-Peng Li,Guang-Peng Zhou,Jie Sun et al.
Shi-Peng Li et al.
It remains unclear as to whether there are differences that exist in the types and functional status of immune cells within different areas of the liver lobules after rejection of liver transplantation. The composition of infiltrating T cel...
Intestinal Protein Characterisation of SARS-CoV-2 Entry Molecules ACE2 and TMPRSS2 in Inflammatory Bowel Disease (IBD) and Fatal COVID-19 Infection [0.03%]
炎症性肠病(IBD)和致命COVID-19感染中SARS-CoV-2受体ACE2和TMPRSS2的肠道蛋白特征分析
Milly J McAllister,Kathryn Kirkwood,Shaun C Chuah et al.
Milly J McAllister et al.
The coronavirus SARS-CoV-2 contributes to morbidity and mortality mainly as a result of immune-pathology in the lungs. Recent data has shown multi-system involvement with widespread viral tropism. Here we present a detailed intestinal prote...
LASSBio-596: a New Pre-clinical Candidate for Rheumatoid Arthritis? [0.03%]
LASSBio-596:一个新的风湿性关节炎临床前候选药物?
Max Denisson Maurício Viana,Alyne Almeida de Lima,Geraldo José da Silva Neto et al.
Max Denisson Maurício Viana et al.
Pain and inflammatory disorders are significant health problems because of prevalence and associated disabilities. In this context, LASSBio-596 is a hybrid compound able to modulate TNF-α and phosphodiesterases 4 and 5, exhibiting an anti-...