Activation of C3 and C5 May Be Involved in the Inflammatory Progression of PCM and GM [0.03%]
C3和C5的活化可能参与了PCM和GM的炎症进展
Xiao-Qiang Li,Hong-Guang Sun,Xiao-Hong Wang et al.
Xiao-Qiang Li et al.
Plasma cell mastitis (PCM) and granulomatous mastitis (GM) are the most common inflammatory diseases constituting nonbacterial mastitis (NBM). However, the pathogenesis of NBM remains unclear. In this study, risk factors for NBM were assess...
Melatonin Attenuates Ropivacaine-Induced Apoptosis by Inhibiting Excessive Mitophagy Through the Parkin/PINK1 Pathway in PC12 and HT22 Cells [0.03%]
褪黑素通过抑制Parkin/PINK1途径介导的过度线粒体自噬来缓解 ropivacaine 诱导的细胞凋亡
Lian Zeng,Jiafeng He,Chenguang Liu et al.
Lian Zeng et al.
Melatonin, as an endogenous circadian indoleamine secreted by the pineal gland, executes extensive biological functions, including antioxidant, anti-inflammatory, anti-tumor, and neuroprotective effects. Although melatonin has been reported...
Quantile-Dependent Expressivity of Serum Interleukin-6 Concentrations as a Possible Explanation of Gene-Disease Interactions, Gene-Environment Interactions, and Pharmacogenetic Effects [0.03%]
基于血清白细胞介素-6浓度的分位数依赖表达性可能是基因与疾病互作、基因与环境互作及药物基因组效应的一种可能解释
Paul T Williams
Paul T Williams
Interleukin 6 (IL-6) is a moderately heritable pleiotropic cytokine whose elevated concentrations in coronary artery disease, peripheral arterial disease, pulmonary arterial hypertension, Eales' disease, Sjògren's syndrome, osteoarthritis,...
Protective Effects of 18β-Glycyrrhetinic Acid on Neonatal Rats with Hyperoxia Exposure [0.03%]
甘草次酸对高氧暴露的新生大鼠的保护作用
Cai Qing,Liu Ziyun,Yu Xuefei et al.
Cai Qing et al.
Bronchopulmonary dysplasia (BPD) is a common devastating pulmonary complication in preterm infants. Supplemental oxygen is a lifesaving therapeutic measure used for premature infants with pulmonary insufficiency. However, oxygen toxicity is...
Calcitonin Gene-Related Peptide Attenuates Hyperoxia-Induced Oxidative Damage in Alveolar Epithelial Type II Cells Through Regulating Viability and Transdifferentiation [0.03%]
降钙素基因相关肽通过调节细胞活力和转分化抑制过氧损伤的肺泡Ⅱ型上皮细胞的作用机制研究
Jian Deng,Shao-Hua Wang,Xue-Mei Zheng et al.
Jian Deng et al.
As a stem cell of alveolar epithelium, the physiological status of alveolar epithelium type II cells (AECII) after hyperoxia exposure is closely related to the occurrence of hyperoxia-induced lung injury and the restoration of normal morpho...
Transcription Factor Specificity Protein 1 Regulates Inflammation and Fibrin Deposition in Nasal Polyps Via the Regulation of microRNA-125b and the Wnt/β-catenin Signaling Pathway [0.03%]
转录因子特异性蛋白1通过调节microRNA-125b和Wnt/β-catenin信号通路调控鼻息肉的炎症及纤维蛋白沉积
Li Song,Xi Wang,Xiangyang Qu et al.
Li Song et al.
Nasal polyps (NPs) are multifactorial soft growths inside the nasal passages and are associated with chronic inflammation that originate from the nasal and paranasal sinus mucosae. This study focused on the role of microRNA (miR)-125b and t...
Autonomic Disbalance During Systemic Inflammation is Associated with Oxidative Stress Changes in Sepsis Survivor Rats [0.03%]
败血症生存大鼠全身炎症期间自主神经失衡与氧化应激的变化有关
Mateus R Amorim,Aline A de Jesus,Nilton N Santos-Junior et al.
Mateus R Amorim et al.
Sepsis affects 31.5 million people worldwide. It is characterized by an intense drop in blood pressure driving to cardiovascular morbidity and mortality. Modern supportive care has increased survival in patients; however, after experiencing...
Correction to: Human Saliva as a Diagnostic Specimen for Early Detection of Inflammatory Biomarkers by Real-time RT-PCR [0.03%]
Correction to: 用实时RT-PCR检测炎症生物标志物的早期诊断唾液标本的校正
Nourin Shakeeb,Prashanth Varkey,Amita Ajit
Nourin Shakeeb
Published Erratum
Inflammation. 2022 Apr;45(2):930. DOI:10.1007/s10753-021-01606-9 2022
CCAAT/Enhancer-Binding Protein Homologous Protein (CHOP) Deficiency Attenuates Heatstroke-Induced Intestinal Injury [0.03%]
CCAAT/增强子结合蛋白同源蛋白（CHOP）缺乏减轻中暑引起的肠道损伤
Yan Cao,Maiying Fan,Yanfang Pei et al.
Yan Cao et al.
The intestine is one of the main target organs involved in the pathological process of heatstroke. CCAAT/enhancer-binding protein homologous protein (CHOP) is involved in endoplasmic reticulum (ER) stress-induced apoptosis. This study aimed...
JNK/Itch Axis Mediates the Lipopolysaccharide-Induced Ubiquitin-Proteasome-Dependent Degradation of Ferritin Light Chain in Murine Macrophage Cells [0.03%]
JNK/Itch轴介导脂多糖诱导的小鼠巨噬细胞中乳铁蛋白轻链的泛素-蛋白酶体依赖性降解过程
Shufen He,Jianqi Xue,Pengxiu Cao et al.
Shufen He et al.
Ferritin, which is composed of a heavy chain and a light chain, plays a critical role in maintaining iron homeostasis by sequestering iron. The ferritin light chain (FTL) is responsible for the stability of the ferritin complex. We have pre...