Targeting Cold-Inducible RNA-Binding Protein Attenuates Pancreatic Fibrosis by Suppressing Pyroptosis in Chronic Pancreatitis [0.03%]
靶向冷诱导RNA结合蛋白通过抑制慢性胰腺炎中的细胞焦亡来减弱胰腺纤维化
Qing Cui,Lin Zhang,Quanyu Guo et al.
Qing Cui et al.
Comprehensive Immune-Phenotyping of Peripheral Lymphocytes in Coronary Artery Disease Reveals Potential Roles of Effector Memory and PD-1⁺ CD4⁺ T Cells [0.03%]
冠心病外周淋巴细胞的全面免疫表型分析揭示效应记忆和PD-1⁺ CD4⁺ T细胞的潜在作用
Xin Huang,Jiaxi Cheng,Leidan Zhang et al.
Xin Huang et al.
CXCL12 Promotes Peripheral Nerve Injury Repair by Inhibiting the Ferroptosis-Inflammation Axis via the ERK/Nrf2 Pathway [0.03%]
CXCL12通过ERK/Nrf2信号通路抑制铁死亡炎性轴促进外周神经损伤修复
Ye Yuan,Yu Jiang,Saisai Du et al.
Ye Yuan et al.
Following peripheral nerve injury (PNI), the ferroptosis-inflammation axis restricts the neural repair process. As a critical neuroregenerative factor, the mechanism by which CXCL12 promotes nerve repair by regulating the ferroptosis-inflam...
RELA as a Diagnostic Biomarker for Parkinson's Disease by Integrating Ferroptosis, Lipid Metabolism, and Neuroinflammation [0.03%]
整合铁死亡、脂质代谢和神经炎症后，RELA可作为帕金森病的诊断生物标志物
Qingfa Chen,Yajun Jing,Weiting Bu et al.
Qingfa Chen et al.
YTHDC2 Deficiency Exacerbates Ulcerative Colitis by Stabilizing RBMS1 mRNA to Drive Epithelial Ferroptosis [0.03%]
YTHDC2缺乏通过稳定RBMS1信使RNA驱动上皮细胞铁死亡从而加重溃疡性结肠炎
Bo Qiu,Zhongbiao Fu,Haihua Wang et al.
Bo Qiu et al.
Integrated Genome-wide Association and Single-cell Transcriptomic Analysis Identifies OAT as Therapeutic Targets for Periodontitis [0.03%]
整合全基因组关联和单细胞转录组分析鉴定出OAT是牙周炎的治疗靶点
Sixian Lou,Yecheng Shen,Sen Li
Sixian Lou
Periodontitis is a chronic inflammatory disease affecting tooth-supporting tissues. Beyond microbial dysbiosis, host metabolic regulation plays a critical role. This study identified ornithine aminotransferase (OAT), a mitochondrial enzyme ...
Deucravacitinib Inhibits Synovial Fibroblast Activation Via TYK2/STAT3 and PI3K/Akt Signaling Pathway [0.03%]
DEUCRAVACITINIB通过TYK2/STAT3和PI3K/AKT信号通路抑制滑膜成纤维细胞活化
Zechao Qu,Jing Wang,Xiaohao Wang et al.
Zechao Qu et al.
P300 in Inflammation: An Updated Perspective on Its Molecular Mechanisms and Therapeutic Potential [0.03%]
P300在炎症中的作用：其分子机制和治疗潜力的最新观点
Ning Zhang,Liang Cao,Dafei Han et al.
Ning Zhang et al.
Carnosic Acid Protects against Bisphenol A-Induced NLRP3 Inflammasome Activation by Attenuating Oxidative Stress in Human Microglial Cells [0.03%]
肉桂酸通过减轻氧化应激抑制双酚A诱导的小胶质细胞NLRP3炎性体的活化作用
Chun-Huei Liao,Han-Ting Wu,Ya-Chen Shih et al.
Chun-Huei Liao et al.
Red Blood Cell-Derived Exosomes Deliver Complement C5 to Exacerbate Neuroinflammation and Neuronal Injury after Intracerebral Hemorrhage [0.03%]
脑出血后红细胞源性外泌体递送补体C5加剧神经炎症和神经元损伤
Qinglan Chen,Jun Min,Xiaomei Lu et al.
Qinglan Chen et al.