Lab-on-a-chip device for microfluidic trapping and TIRF imaging of single cells [0.03%]
用于微流控单细胞捕获和TIRF成像的芯片实验室设备
Dustin Dzikonski,Riccardo Zamboni,Aniket Bandyopadhyay et al.
Dustin Dzikonski et al.
Total internal reflection fluorescence (TIRF) microscopy is a powerful imaging technique that visualizes the outer surface of specimens in close proximity to a substrate, yielding crucial insights in cell membrane compositions. TIRF plays a...
Deciphering the allosteric dynamics of GPR120-fatty acid interactions within a bilayer nanogold electrochemical receptor biosensor: the impact of replacing tryptophan 198 with proline [0.03%]
双层纳米金电化学生物传感器内GPR120-脂肪酸别构动力学的破译：198位色氨酸被脯氨酸取代的影响
Wei Xu,Dan Meng,Ming Li et al.
Wei Xu et al.
GPR120 is a free fatty acid receptor capable of signalling excess fatty acids. GPR120 can be activated by various types of free fatty acids, causing intracellular signal transduction and exerting energy regulation, immune homeostasis, and n...
Microfluidic biosensors: revolutionizing detection in DNA analysis, cellular analysis, and pathogen detection [0.03%]
微流控生物传感器：在DNA分析、细胞分析和病原体检测中的革命性检测技术
Reza Didarian,Mehdi Tayybi Azar
Reza Didarian
Microfluidic chips have emerged as versatile and powerful tools that enable the precise manipulation of fluids and bioparticles at the microscale. Their impact on detection applications is profound, offering advantages such as miniaturizati...
Microneedle electrodes: materials, fabrication methods, and electrophysiological signal monitoring-narrative review [0.03%]
微针电极：材料、制造方法及生理信号监测-叙述性综述
Om Prakash Singh,Ismail M El-Badawy,Sornambikai Sundaram et al.
Om Prakash Singh et al.
Flexible, microneedle-based electrodes offer an innovative solution for high-quality physiological signal monitoring, reducing the need for complex algorithms and hardware, thus streamlining health assessments, and enabling earlier disease ...
Design, fabrication, and characterization of a user-friendly microfluidic device for studying liver zonation-on-chip (ZoC) [0.03%]
用于研究芯片上的肝区化(ZoC)的用户友好型微流控设备的设计、制造和特性分析
Reza Mahdavi,Sameereh Hashemi-Najafabadi,Mohammad Adel Ghiass et al.
Reza Mahdavi et al.
Liver zonation is a fundamental characteristic of hepatocyte spatial heterogeneity, which is challenging to recapitulate in traditional cell cultures. This study presents a novel microfluidic device designed to induce zonation in liver cell...
Pratik Kusumanchi,Jesper Guldsmed Madsen,Toke Bek et al.
Pratik Kusumanchi et al.
Retinal prosthesis has been one of the medical strategies aimed at restoring some degree of vision for patients affected by retinal degenerative diseases, such as Retinitis Pigmentosa (RP) and age-related macular degeneration (AMD), which a...
Jongho Park,Jingzong Zhang,Beomjoon Kim
Jongho Park
Recently, photodynamic therapy (PDT) which involves a photosensitizer (PS), a special drug activated by light, and light irradiation has been widely used in treating various skin diseases such as port-wine stain as well as cancers such as m...
Daísy Camargo Ferreira,Marina Ribeiro Batistuti Sawazaki,Bassam Bachour Junior et al.
Daísy Camargo Ferreira et al.
The overexpression of Human Epidermal Growth Factor Receptor 2 (HER2) protein is specifically related to tumor cell proliferation in breast cancers. Its presence in biological serum samples indicates presence or progression of cancer, becom...
Liquid biopsy technologies: innovations and future directions in breast cancer biomarker detection [0.03%]
液体活检技术在乳腺癌生物标志物检测中的创新及未来方向
Linhong Cao,Qingli Duan,Zixin Zhu et al.
Linhong Cao et al.
Globally, breast cancer is the most frequent type of cancer, and its early diagnosis and screening can significantly improve the probability of survival and quality of life of those affected. Liquid biopsy-based targets such as circulating ...
Quantitative investigation of a 3D bubble trapper in a high shear stress microfluidic chip using computational fluid dynamics and L*A*B* color space [0.03%]
基于计算流体动力学和Ltextsuperscript{* Atextsuperscript{*Btextsuperscript{*}}色彩空间的高剪切应力微流控芯片3D气泡捕获器定量研究
Warisara Boonsiri,Hein Htet Aung,Jirasin Aswakool et al.
Warisara Boonsiri et al.
Microfluidic chips often face challenges related to the formation and accumulation of air bubbles, which can hinder their performance. This study investigated a bubble trapping mechanism integrated into microfluidic chip to address this iss...