Au-MnOx nanozyme-based multifunctional hydrogel for NIR-II laser triggered tumor radiotherapy sensitization [0.03%]
基于Au-MnOx纳米酶的多功能水凝胶用于近红外激光触发的肿瘤放射增敏治疗
Zhan Xiao,Xiaolong Zhou,Lingbo Zhang et al.
Zhan Xiao et al.
Radiotherapy (RT) is widely used for malignant tumors ablation in the clinic. However, redundant doses of X-rays might cause irreversible side effects in the periphery of tumor sites. To address this, the convergence of low-dose RT with a n...
3D-Printed CRISPR-based detection system powered by a reusable handwarmer [0.03%]
一种基于CRISPR的检测系统，由可重复使用的暖手器提供动力的3D打印装置
Daniel Schreiber,Rui Yang,Xin Guan et al.
Daniel Schreiber et al.
Nucleic acid-based molecular diagnostics are essential for the prevention, early detection, and treatment of cancer and infectious diseases. In this study, we developed a 3D-printed, electricity-free detection system for CRISPR-based nuclei...
Automation of electrothermal cell sheet manipulator for seamless tissue assembly and handling [0.03%]
用于无缝组织装配和处理的电热细胞片操作机器人的自动化
Sehong Kang,Min Ku Kim,Chi Hwan Lee et al.
Sehong Kang et al.
The manipulation of fragile biological tissues such as engineered cell sheets remains a major challenge for regenerative medicine and tissue engineering. Manual handling with tools like tweezers often induces wrinkling or tearing, compromis...
Non-contact culturing of vascular endothelial cells on wall surface following retention using acoustic radiation force and lipid bubbles [0.03%]
声辐射力结合脂质微泡捕获血管内皮细胞并在壁面非接触培养
Shunya Watanabe,Yuki Ichikawa,Kota Konishi et al.
Shunya Watanabe et al.
For application in the fabrication of artificial blood vessels, we developed a method for non-contact culturing of vascular endothelial cells following a process of non-contact retention. Utilizing the propulsive force acting on cells under...
Lateral flow immunoassay based on large-sized Au@Ag nanoparticles for stable colorimetric enhanced detection of D-dimer [0.03%]
一种基于大尺寸Au@Ag纳米颗粒的稳定彩色免疫层析检测D-二聚体的方法
Jingfei Zhang,Xuanxu Nan,Li Yang et al.
Jingfei Zhang et al.
The Lateral flow immunoassay (LFIA) has been widely used in environmental monitoring and disease diagnosis due to its advantages of low cost, simple operation, and convenience. However, its accuracy and sensitivity remain major challenges t...
Advances in microengineered platforms for 3D tumor production and modeling [0.03%]
用于三维肿瘤制备和建模的微工程平台研究进展
Xufang Liu,Meilin Sun,Jinwei Zhang et al.
Xufang Liu et al.
The facile and large-scale construction of in vitro biomimetic three-dimensional (3D) tumor models has been pursued for cancer exploration, clinical/preclinical drug screening and discovery, as well as personalized therapy. The utilization ...
Ultra-low detection of SARS-CoV-2 Virus Like Particles (VLPs) with functionalized gold plasmonic nanoresonator array [0.03%]
具有功能化的黄金等离激元纳米谐振子阵列的SARS-CoV-2病毒样颗粒(VLPs)的超灵敏检测技术
Dipanjan Nandi,Jiaxin Fan,Seongdae Kang et al.
Dipanjan Nandi et al.
Localized surface plasmon resonance (LSPR) sensors have good potential for label-free non-invasive detection of biomolecules, healthcare diagnosis, disease monitoring, gas sensing, and food safety. For detection of low concentration small-s...
Evaluation of mucoadhesive properties of Opuntia-carrageenan superporous hydrogel on gastrointestinal mucosa [0.03%]
欧朴亭-琼脂糖胃肠粘膜多孔水凝胶的黏附性能评估
Itishree Jogamaya Das,Trishna Bal,Himansu Bhusan Samal et al.
Itishree Jogamaya Das et al.
This study evaluates the mucoadhesive properties of Opuntia-carrageenan superporous hydrogel (OPM-CRG SPH) in vitro and in vivo, assessing its potential as a biomaterial for gastrointestinal (GI) mucoadhesive drug delivery systems. Mucoadhe...
Engineering vascularized brain tumor organoids: bridging the gap between models and reality [0.03%]
工程化血管化的脑肿瘤类器官：弥合模型与现实之间的差距
Amirali Hariri,Atefeh Zarepour,Arezoo Khosravi et al.
Amirali Hariri et al.
Traditional two-dimensional cultures and patient-derived xenografts fail to fully mimic the complexity of the tumor microenvironment, limiting their utility in drug discovery and personalized medicine. Recent breakthroughs in three-dimensio...
AuNPs-TiS2 modified label-free ultrasensitive electrochemical immunosensor for carcinoembryonic antigen (CEA) detection [0.03%]
一种新型的用于检测癌胚抗原(CEA)的无标记超灵敏电化学免疫传感器：AuNPs-TiS2修饰型免疫传感器
Ulviye Ki̇li̇mci̇,Baha Öndeş,Yüksel Şahi̇n et al.
Ulviye Ki̇li̇mci̇ et al.
In this study, a novel immunosensor for carcinoembryonic antigen (CEA) determination was designed, and the synergistic effect of zero-dimensional gold nanoparticles and two-dimensional nanomaterials TiS2 was investigated. In this regard, go...