Fabrication of a novel porous silicon biomembrane for applications in organ-on-chip technology [0.03%]
一种新型多孔硅生物膜的制备及其在芯片器官技术中的应用研究
Marcus A C Williams,Cooper Wiens,Sahra Genc et al.
Marcus A C Williams et al.
Conventional in vitro and preclinical animal models often fail to accurately replicate the complexity of human diseases, limiting the success of translational studies and contributing to the low success rate of clinical trials (Ingber 2016)...
Distance-dependent spatial analysis of micropattern-generated shockwave for cell-type specific intracellular delivery [0.03%]
基于距离的用于细胞类型特异性胞内传递的微图案诱导冲击波的空间分析方法研究
Aniket Mishra,Shunya Okamoto,Takayuki Shibata et al.
Aniket Mishra et al.
Intracellular delivery of therapeutic materials remains challenging, with conventional micropattern-assisted optoporation methods making it difficult to analyze the spatial effects of individual laser pulses. Here, we show that pigmented SU...
Ziyan Zhang,Yufeng Zhou
Ziyan Zhang
Membrane-bound extracellular vesicles (EVs) are more than mere messengers; they are the carriers of intercellular communication, carrying biomolecules for regulatory processes. They have potential in biomarker discovery and disease diagnosi...
Ata Ullah,Jade Bookwalter,Himanshu Sant et al.
Ata Ullah et al.
Glioblastoma is a highly malignant brain tumor with limited survival rates due to challenges in complete surgical excision, high recurrence (> 90%), and the inefficacy of systemic drug delivery. Significant efforts have been made to develop...
Chlorhexidine loaded nanomaterials for dental plaque control: enhanced antibacterial activity and biocompatibility [0.03%]
负载氯己定的纳米材料用于牙菌斑控制：增强抗菌活性和生物相容性
Aram Rostami,Vahid Molabashi,Saber Ganji et al.
Aram Rostami et al.
Chlorhexidine (Chx) is a commonly used antimicrobial agent in dentistry, but its effectiveness can be limited due to rapid clearance, potential cytotoxicity, and insufficient tissue penetration. Nanomaterials have been developed as carriers...
Novel dual-lumen microneedle delivers adeno-associated viral vectors in the guinea pig inner ear via the round window membrane [0.03%]
一种新的双腔微针可通过圆窗膜将腺相关病毒载体递送至 Guinea Pig 的内耳中
Daniella R Hammer,François Voruz,Aykut Aksit et al.
Daniella R Hammer et al.
The clinical need for minimally invasive inner ear diagnostics and therapeutics has grown rapidly in recent years, particularly with the development of gene therapies for treating hearing and balance disorders. These therapies often require...
Lab on chips for liquid biopsy: a flexible and customized approach through microfabrication [0.03%]
基于微加工的液态活检芯片：灵活、定制化的实验室解决方案
Valeria Garzarelli,Alessia Foscarini,Vanessa Indirli et al.
Valeria Garzarelli et al.
Cancer early detection is one of the most challenging purposes of preventive medicine. Liquid biopsy represents a revolutionary approach, fostering access to early screening and increasing patients' compliance, two crucial issues in reachin...
A 3D vascularized tumor spheroid microfluidic platform for head and neck cancer research: new insights [0.03%]
一种用于头颈部癌症研究的三维血管化肿瘤微流控平台：新的认识和见解
Jooin Bang,Jiyoung Yeo,Su Ji Lee et al.
Jooin Bang et al.
Conventional in vitro cancer models often fail to replicate the complexity of the tumor microenvironment. We have developed a 3D micro-engineered vascularized organoid chip (VOC) platform to enhance the physiological relevance of in vivo tu...
Small form factor implantable neural probe with efficient flip chip µLED for in vivo optogenetics [0.03%]
一种用于在体光遗传学的高效植入股式微发光二极管小型化植入式神经探针
Mafalda Abrantes,Tiago Pereira,Patrícia Silva et al.
Mafalda Abrantes et al.
Sustained - release microspheric gel of meloxicam: Preparation, evaluation in vitro and in vivo [0.03%]
美洛昔康微球凝胶缓释制剂的制备及体内外评价研究
Peng Zheng,Yongtao Wei,Keren Cao et al.
Peng Zheng et al.