Two-photon lithography-fabricated deterministic lateral displacement microfluidic system for efficient minicell purification in cancer therapy [0.03%]
用于癌症治疗的双光子光刻制造的确定性侧向位移微流体系统，用于有效的最小细胞纯化
Sharaj Hegde Sharavu,Sagar Bhagwat,Sebastian Kluck et al.
Sharaj Hegde Sharavu et al.
Chromosome-less minicells, derived from aberrant polar division events of bacterial cells, have emerged as promising nanocarriers for targeted cancer drug delivery due to their unique characteristics. A major challenge in their purification...
Uncloggable ventriculoperitoneal shunt system for hydrocephalus via an integrated soft robotic device: CLEARS device [0.03%]
一种用于脑积水的集成软机器人装置的不可堵塞的室腹分流系统：CLEARS设备
Yau C Yun,David R Santiago-Dieppa,Minghao Li et al.
Yau C Yun et al.
Ventriculoperitoneal (VP) shunt obstruction, often caused by protein and fat accumulation at the ventricular catheter ports, impedes cerebrospinal fluid (CSF) outflow, increases intracranial pressure (ICP), and leads to hydrocephalus. Curre...
Detection of EGFR mutations at pM concentration in ten minutes using a microfluidic concentration and separation module [0.03%]
一种微流控浓缩和分离模块用于十分钟内检测皮摩尔浓度的EGFR突变
Jeffrey Teillet,Anne Pradines,Naima Hanoun et al.
Jeffrey Teillet et al.
Epidermal growth factor receptor (EGFR) mutation detection is now commonly used in the management of cancer patients, particularly those diagnosed with non-small cell lung cancer. Molecular beacon-based sensing is direct and rapid, but its ...
Aptamer and graphene-enhanced field-effect device for the sensitive and label-free detection of adenosine triphosphate [0.03%]
一种用于三磷酸腺苷敏感和无标记检测试剂的适配器和石墨烯增强场效应设备
Muhammad Noman Bashir,Miaomiao Wang,Yating Chen et al.
Muhammad Noman Bashir et al.
The urgent need for adenosine triphosphate (ATP) detection spans various fields, particularly in biology and medicine. Developing a simple, quick, label-free, and highly sensitive biosensor for ATP detection is crucial. In this study, we cr...
Microfluidic and lab-on-a-chip devices for detection and diagnosis of periprosthetic joint infections [0.03%]
用于人工关节周围感染检测和诊断的微流控及芯片实验室设备
Luca Pellegrino,Alberto Bulgarelli,Cristina Belgiovine et al.
Luca Pellegrino et al.
Periprosthetic joint infection (PJI) is a serious complication of prosthetic joint implantation, which poses a significant burden on both individuals and society. Effective treatment relies on the rapid identification of the underlying caus...
Electronic selection of viable Legionella cells by a video-based, quantifiable dielectrophoresis approach [0.03%]
基于视频的定量介电泳技术筛选活性军团菌细胞
Madeline Altmann,Anders Henriksson,Peter Neubauer et al.
Madeline Altmann et al.
The accurate selection of living from dead pathogenic cells is crucial as exemplified in the context of detecting Legionella bacteria, which can be present in various water facilities and pose a threat to public health by causing severe res...
Recent progress in electrochemical assessment of DNA based on nanostructured sensors [0.03%]
基于纳米结构传感器的电化学DNA评估研究新进展
Lue Wang,Waye Zhang
Lue Wang
Screening the amount of DNA closely related to early diagnosis of diseases or decoding information in target DNA sequences for biological medicine, infectious identification, or forensic analysis are highly essential in our daily life. This...
Isolation of therapeutic extracellular vesicles using nanoporous membranes with uniform nanopores [0.03%]
采用具有均一纳米孔的纳滤膜分离治疗性外泌体
Gyeong Won Lee,KyoIck Koo,Soo-Eun Sung et al.
Gyeong Won Lee et al.
Extracellular vesicles (EVs) are nanosized particles secreted by most cells for information transmission, which affects the microenvironment. EVs are known to follow the characteristics and conditions of their mother cells and have attracte...
Electrochemical paper-based immunosensor engineered with zinc oxide-nanoflower structures for the detection of field isolated Pasteurella multocida [0.03%]
一种用于检测多杀巴斯德菌的基于纸基电化学生物传感器的新方法
Manjeet Chahar,Mohd Rahil Hasan,Sameer Khan et al.
Manjeet Chahar et al.
In this research, we created a paper-based electrochemical immunosensor for detecting Pasteurella multocida antigen (Pm-Ag). Bacteria were obtained from a buffalo nasal swab, and the antigen was prepared and then injected into rabbits to in...
Separation of mononuclear cells from progenitor products by a novel inertial microfluidic method [0.03%]
一种新型惯性微流体方法用于从造血干细胞和祖细胞制品中分离单个核细胞
Nilgün Okşak,Sultan Sahin Keskin,Esin Cetin Aktas et al.
Nilgün Okşak et al.
Mononuclear cells (MNCs), a type of leukocyte, require enrichment owing to their rarity for research and clinical applications. The enrichment of MNCs is generally performed via conventional methods (e.g., density gradient centrifugation). ...